San Francisco 49ers vs Los Angeles Rams: Predictions and Odds (NFL Week 6)

This game goes to the 49ers by 4, their solid defense and two-headed rushing monster will be too much for the Rams to handle. Final score: 49ers 34, Rams 30.

How to Watch: 49ers vs Rams

What: San Francisco 49ers at Los Angeles Rams
When: Sunday, October 13 at 4:05 pm ET
Where: Los Angeles Memorial Coliseum in Los Angeles, California
How (TV): FOX

Latest Point Spread 49ers vs Rams

49ers +3.5, Rams -3.5

You can’t get a better Week 6 matchup than this NFC West doozie that pits the underrated and undefeated San Francisco 49ers against the defending NFC Champion Los Angeles Rams who have already (surprisingly) lost two games on the season.

49ers quarterback Jimmy Garopolo is healthy now, but he hasn’t had to do much given his team’s rushing attack and defense have been carrying the load thus far, whereas Rams quarterback Jared Goff has been highly productive, leading his team to more wins than losses while some doubts float around his team’s current defensive capabilities.

Let’s take a quick look at how these two teams are set up to face each other in Week 6.

You can also have a look at NFL Week 6 – Point Spreads and Picks.

The 4-0-0 San Francisco 49ers

The undefeated San Francisco 49ers are coming off a 31-3 trouncing of the Cleveland Browns on Monday Night Football where they showed off an aggressive defensive line (featuring rookie defensive end Nick Bosa) and a killer two-headed rushing monster that has them leading the league in on-the-ground yards.

With such a solid running game, quarterback Jimmy Garopolo has not had to do much yet this season, but the most important feat he’s been able to accomplish is to stay healthy, something he struggled with over the 2018 season.

This game on Sunday against the Los Angeles Rams will be the 49ers’ first divisional matchup this season, so if they can win this one, they will begin to shut up the doubters who whisper that San Francisco’s had it easy so far in 2019.

The 3-2-0 Los Angeles Rams

The Los Angeles Rams have looked beatable these last few weeks, mostly because their quarterback keeps throwing it to the other team, Jared Goff with 4 interceptions in the last two games.

Despite his 7 picks overall in five games, Goff has been highly effective this season, completing 63.1 percent of his 222 attempts for 1,649 yards and 7 touchdowns, ranked the 3rd most productive quarterback in the league right now.

It’s the Rams’ defense that seems to be taking some time off these days – they’re ranked 13th this season overall and 15th against the run and so far only have 4 total interceptions (T-11th most) and 11 total sacks (T-20th most), so Aaron Donald and company will have to step up against this rush-heavy 49ers team if they expect to win on Sunday.

Check out also: NFL Top 100 Players of 2019.

What’s at Stake for 49ers vs Rams?

These two teams have met 139 total times (including 1 postseason game), with Los Angeles winning 67 of those games and San Francisco winning 69 times.

The last time these two teams played was in December of the 2018 season in Los Angeles, where the Rams won by a score of 48-32 on their eventual way to the Super Bowl.

If the 49ers win this matchup, they’ll have beaten a worthy divisional opponent and move to 5-0-0 and be alone and undisputed atop the NFC West, much to the surprise of just about everybody.

But if the Rams come out winners in this one, they’ll be 4-2-0 and a legitimate three-way battle for the NFC West begins with the Seattle Seahawks and these pesky 49ers.

Questions to Answer

Who’s favored to win this Week 6 49ers-Rams matchup?

Which team has a better offense? Defense? Special teams?

Which team’s quarterback is more likely to lead his team to victory?

We’re going to briefly compare the 49ers and the Rams next and attempt to answer those questions and more.

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Offensive Stats Comparison – 49ers vs Rams

San Francisco 49ers Overall Offense

  • Ranked 16th overall in 2018
  • Ranked 4th overall in 2019

Passing attack: The San Francisco 49ers have the 22nd ranked passing offense in the league right now, averaging 227.2 yards per game through the air after five weeks.

Quarterback Jimmy Garopolo is healthy and is currently ranked the 25th most productive passer in the league having completed 78-of-113 for 920 yards and 7 touchdowns with 4 interceptions and a completion percentage of 69.0.

The 49ers leading receiver after five weeks is tight end George Kittle, who is currently 58th in the league with 23 catches for 235 yards and 1 touchdown.

Rushing attack: The 49ers’ rushing attack is ranked first in the league after averaging 200.0 yards on the ground per game.

Matt Breida is the 49ers’ best runner and he is currently the 12th best in the NFL with 52 carries for 340 yards and 1 rushing touchdown, averaging 6.5 yards per carry, with his backfield partner Raheem Mostert, ranked 27th right now, getting 41 carries for 236 yards and no touchdowns, averaging 5.8 yards per carry.

San Francisco has scored 127 total points this season, or 31.8 per game, which is the 11th best total in the NFL.

San Francisco Offensive Injuries

Listed as questionable for Week 6: no San Francisco offensive players are currently listed as questionable for Week 6.

Injury notes: offensive tackle Joe Staley (lower leg) and center Kyle Nelson (suspension) are listed as OUT, tight end Garrett Celek (back) is listed as PUP-R, while running back Jerick McKinnon (knee – ACL), wide receivers Jalen Hurd (back), Shawn Poindexter (knee) and Trent Taylor (foot) and offensive tackles Shon Coleman (ankle) and Andrew Lauderdale (undisclosed) have been placed on the injured reserve list.

Los Angeles Rams Overall Offense

  • Ranked 2nd overall in 2018
  • Ranked 5th overall in 2019

Passing attack: Los Angeles has the 2nd best passing attack in the league right now after averaging 317.4 yards through the air each game.

Quarterback Jared Goff has completed 140-of-222 passes for 1,649 yards and 7 touchdowns with 7 interceptions and a completion percentage of 63.1.

The Rams’ best receiver is currently Cooper Kupp, who has caught 41 passes for 505 yards with 4 touchdowns in five weeks, ranked 4th among NFL receivers right now.

Rushing attack: Los Angeles has the 22nd ranked rushing attack, so far averaging 96.2 rushing yards per game.

Todd Gurley is the Rams’ best runner and now he is the 18th best in the NFL with 64 carries for 270 yards and 5 touchdowns, averaging 4.2 yards per carry.

Los Angeles has scored 146 points in 2019, averaging 29.2 per game, which is the 5th highest average in the league right now.

Los Angeles Offensive Injuries

Listed as questionable for Week 6: wide receiver Brandon Cooks (concussion).

Injury notes: wide receiver Alex Bachman (undisclosed) has been placed on injured reserve.

Offensive Advantage

After watching the 49ers show no mercy on the Cleveland Browns in Week 5 with their run game, they have the slight advantage over the Rams in Week 6, but watch out for Goff’s arm and Gurley’s legs nonetheless.

Defensive Stats Comparison – 49ers vs Rams

San Francisco 49ers Overall Defense

  • Ranked 28th overall in 2018
  • Ranked 2nd overall in 2019

Pass coverage: The 49ers have the 2nd best pass defense in 2019 so far, allowing opponents to throw for 175.8 yards through the air per game.

San Francisco’s defense has 7 team picks and they have 13 sacks total.

Run coverage: The 49ers are the 5th best NFL team against the run right now after allowing opponents to run for 81.8 yards per game.

San Francisco has allowed its opponents to score 57 total points, or 14.2 per game, which is 2nd lowest in the NFL.

49ers Defensive Players to Watch

So far, the best tackler for the 49ers has been middle linebacker Fred Warner, who has posted 25 total tackles this season (1 for a loss), plus 2 passes defended and a forced fumble.

The entire San Francisco defensive front line is worth watching, but keep your eyes on the lookout for rookie defensive end Nick Bosa, who has 3.0 sacks and 8 tackles with a forced fumble and a fumble recovery, and defensive tackle DeForest Buckner, who also has 3.0 sacks plus 18 tackles with 2 forced fumbles and a fumble recovery.

He may be a bit older (31-years old) for a cornerback, but Richard Sherman is still fast and ready to play with the youngsters, already with 2 interceptions on the season, one of those a 31-yard pick-six, plus 8 passes defended and 15 tackles.

49ers Defensive Injuries

Listed as questionable for Week 6: currently, no San Francisco defensive players are listed as questionable.

Injury notes: cornerback Ahkello Witherspoon (foot) is listed as out, while defensive end Kentavius Street (knee) and cornerbacks Tim Harris (groin) and Jason Verrett (knee) have been placed on injured reserve.

Los Angeles Rams Overall Defense

  • Ranked 20th overall in 2018
  • Ranked 13th overall in 2019

Pass coverage: The Rams’ defense is 16th best against the pass, allowing their opponents to throw for an average of 243.2 yards per matchup.

Los Angeles’ defense has 4 interceptions on opposing quarterbacks and they have 11 total sacks after five weeks.

Run coverage: The Rams are 15th best against a rushing attack, allowing opponents to run for an average of 106.8 yards per game.

Los Angeles has allowed its opponents to score 134 total points this season, or 26.8 per matchup, which is 26th fewest in the NFL.

Rams Defensive Players to Watch

Rams’ strong safety John Johnson is a tackling machine, already with 42 total tackles, plus two interceptions and 4 passes defended.

Los Angeles Rams’ outside linebacker Clay Mathews has the fourth most sacks in the league with 6.0, plus 2 forced fumbles and 19 tackles, though he is listed as out due to a jaw injury (see below).

Inside linebacker, Cory Littleton stays busy for the Rams, so far with an interception and 7 passes defended with 41 total tackles, a forced fumble and a fumble recovery.

Rams Defensive Injuries

Listed as questionable for Week 6: linebacker Bryce Hager (shoulder) and safety Taylor Rapp (ankle).

Injury notes: linebacker Clay Matthews (jaw) is listed as OUT, while linebackers Josh Carraway (Achilles), Micah Kiser (pectoral) and Justin Lawler (foot) have been placed on injured reserve.

Defensive Advantage

San Francisco has the better defense right now, allowing opponents to score over 12 points less per game than the Rams have this season.

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Special Teams Stats Comparison – San Francisco 49ers vs Los Angeles Rams

Punters

San Francisco’s punter, Mitch Wishnowsky, is in his first NFL season and so far, he has punted 11 times this season for a net average of 43.5 yards per punt, which is 12th best in the league.

Los Angeles’ punter, Johnny Hekker, is in his ninth NFL season, fifth with the Rams, and this season he has punted 13 times for a net average of 39.4 yards per punt, which is the 28th best in the league.

Placekickers

San Francisco’s placekicker, Robbie Gould, is in his fifteenth NFL season, his third with the 49ers.

Gould has made 7-of-12 field goals so far this season, his longest a 47 yarder, and so far, he has missed zero extra point attempts (14/14).

Los Angeles’ placekicker, Greg Zuerlein, is in his ninth NFL season, his fifth with the Rams.

Zuerlein is 12-of-15 so far this season, his longest a 58-yarder, and he has missed zero extra point attempts (14/14).

Punt Returners

San Francisco’s punt returner, wide receiver Richie James, is ranked 9th in average punt return yardage this season.

James has returned 8 punts for 89 yards, averaging 11.1 yards per return, his longest for 32 yards.

Los Angeles’ punt returner, wide receiver JoJo Natson, is ranked 16th in average punt return yardage this year.

Natson has returned 8 punts for 77 yards, averaging 9.6 yards per return, his longest for 32 yards.

Special Teams Advantage

Both of these teams have veteran placekickers who can apparently make extra points but who have missed far too many field goals to give their team an advantage, so right now neither team is ahead on special teams.

Final Game Analysis for 49ers vs Rams

Why Will the 49ers Win this Game?

The San Francisco 49ers have been underestimated for the last two seasons because their franchise quarterback has been injured and their defense wasn’t much to speak of, but all that has changed in 2019 and this team can win every game it plays, even against these Rams.

The San Francisco defensive front will have to make Jared Goff extremely uncomfortable, so much so that he rushes his throws, and that’s when the league’s second-best pass coverage will do their job and take the ball away (or at least swat it down).

The Rams are not very good against the run and the 49ers have the best rushing attack in the league, so the formula for victory seems pretty simple here.

Why Will the Rams Win this Game?

The Los Angeles Rams will win this game because they are way better than they have been playing and they have the second-best passing attack in the league, which will be fun to watch against the 49ers’ second-best passing defense.

The Los Angeles Rams will also win this one because they typically do well against divisional rivals whereas the 49ers do not, San Francisco having gone 2-10 over the last two seasons against teams from the NFC West.

To win, though, the Rams will need a big game from Gurley, because San Francisco is no joke against the run (just ask the Browns’ Nick Chubb about last week) and it will take everything that Sean McVay can game plan to get the home W out of this one.

This Game Goes To

San Francisco 49ers by 4, their solid defense and two-headed rushing monster will be too much for the Rams to handle right now, even at home.

John Breech of CBS Sports predicts the score as Rams 34, 49ers 27

My prediction for the final score is 49ers 34, Rams 30.

San Francisco 49ers vs Los Angeles Rams – Odds

The latest odds for the 49ers vs Rams are provided by 888Sport NJ, DraftKings, and Unibet NJ.

Good Luck!

Money Line:

Sportsbook49ersRams
888Sport NJ+165-205
DraftKings+170-195
Unibet NJ+165-205

Point Spread:

Sportsbook49ers

+3.5

Rams

-3.5

888Sport NJ-110-110
DraftKings-110-110
Unibet NJ-110-110

Total Points:

SportsbookOver

50.5

Under

50.5

888Sport NJ-114-107
DraftKings-114-107
Unibet NJ-114-107

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