Chivas Guadalajara vs. Cruz Azul Prediction: Trip to the Final on the Line

Saturday evening, the second leg of the Liguilla semifinal will take place at Estadio Akron as Chivas welcomes Cruz Azul. The first leg finished level after 90 minutes,  ending 2-2. 

• Chivas Guadalajara can advance with another draw, as they are the higher seed 

• Cruz Azul is aiming for its first finals appearance since the 2024 Clausura season 

Here, we will break down the betting odds and share our favourite picks for Chivas Guadalajara vs. Cruz Azul.

Chivas Guadalajara vs. Cruz Azul Betting Odds for Saturday, May 16

The oddsmakers are favouriting the hosts to escape this match unscathed in the draw no bet market. Chivas are listed at -180 to win or return our stake with a draw, while the visitors are priced at +140 for the same outcome.

Chivas Guadalajara vs. Cruz Azul Odds

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Chivas Guadalajara vs. Cruz Azul Betting Prediction

As Cruz Azul and Chivas Guadalajara gear up for a fiery semifinal clash, attention now turns to the betting markets in search of the most promising opportunities for a profitable wager.

Chivas Guadalajara Preview

Despite drawing the first liguilla semifinal tilt, Gabriel Milito and his crew still hold the advantage heading into Saturday, as they finished higher in the standings than their opponent. Both of the Sacred Herd’s goals were inside the opposition's six-yard box as Ángel Sepúlveda and Santiago Sandoval both contributed to the scorers’ sheet on Wednesday. 

This could be Santiago Sandoval’s introduction to the big stage with the displays he keeps manufacturing. The 18-year-old striker has cataloged three tallies in his previous two outings. The timing of his arrival couldn’t have happened at a better moment, as Chivas is out with five regulars who are away with the national team. 

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Cruz Azul Preview

Joel Huiqui’s men extended their unbeaten run against the Sacred Herd to eight on Wednesday evening. Cruz Azul has found some success on the road during the 2026 Clausura season, collecting three wins, but has suffered one setback in nine away dates. 

Christian Ebere has emerged as a lethal threat for the opposition to contain. He scored his third postseason goal during the first leg in his 89 minutes of work. José Paradela has been the most inform member of La Máquina of late, scoring or assisting in four consecutive appearances. The high-pressing midfielder is known to frustrate the opposing backline with his high-pressing tactics, giving his side more opportunities to breach the keeper.

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Chivas Guadalajara vs. Cruz Azul - My Pick

• Chivas Guadalajara vs. Cruz Azul pick: Cruz Azul draw no bet (+140) at FanDuel

We feel Cruz Azul has a real shot to eliminate Chivas Guadalajara on Saturday, with major factors lining up in their favour heading into the decisive Liga MX semifinal. La Máquina possesses the edge in the middle of the park, allowing them to dictate possession and tempo.

Cruz Azul showed resilience and heart. They fell behind twice and they responded both times. Those mental qualities often decide playoff series, along with how battle-tested this side is, which they showed when they went on to claim last year's CONCACAF Champions Cup. 

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How to Watch Chivas Guadalajara vs. Cruz Azul

• When: May 16, 9.07 pm ET 

• Where: Estadio Akron 

• TV: Univision Networks (Univision, UniMás, TUDN), CBS Sports, Fox Sports, NBC Universal, ViX, Peacock