Cruz Azul vs. Chivas Guadalajara Prediction: Powerhouses Face Off in Liguilla Semifinal

Wednesday evening, the Sacred Herd will travel to the capital of Mexico to clash against Cruz Azul at the Estadio Banorte. The most recent encounter was back in February, when La Máquina secured a 2-1 home win.

• Cruz Azul are on a roll, across all competitions, they are unbeaten in their last seven

• Chivas Guadalajara will be aiming for its first road win since March 21 

Here, we will break down the betting odds and share our favourite picks for Cruz Azul vs. Chivas Guadalajara.

Cruz Azul vs. Chivas Guadalajara Betting Odds for Wednesday, May 13

The hosts are favoured to take the first leg listed at +110 to win. The visitors are priced at +230 while the draw is marked at +260.

Cruz Azul vs. Chivas Guadalajara Odds

Odds for Cruz Azul vs. Chivas Guadalajara are provided by FanDuel Sportsbook. Sign up for a FanDuel account and clam your bonus: Bet $5, Get $150 in Bonus Bets.

Read more about FanDuel Promo Code here.

If you are in a state where FanDuel is not yet legal, we recommend trying Kalshi, one of the best prediction markets in the US. Sign up using Kalshi promo code WSN to get a $10 bonus after making 100 contracts.

Cruz Azul vs. Chivas Guadalajara Betting Prediction

As Cruz Azul and Chivas Guadalajara prepare to collide in a fiery playoff showdown, attention now shifts to the betting markets in search of the most promising opportunities for a profitable wager.

Cruz Azul Preview

Joel Huiqui’s men found a way to get past a pesky Atlas F.C. side over the two-legged quarterfinal encounter. Winning on a 4-2 aggregate, Cruz Azul are 180 minutes away from reaching their first finals appearance since the 2024 Clausura season. Over the weekend, the nine-time Liga MX winners engineered their first clean sheet since March 7th.

José Paradela was the lone player to breach the keeper on Saturday against Atlas, as he extended his goal contribution streak to three straight matches. Also helping Cruz Azul secure their spot in the semifinals was a standout performance from Kevin Mier between the sticks. The Colombian netminder stopped all five shots he faced, which was quite the turnaround as he surrendered two goals from two shots during the first leg.

Get $150 in Bonus Bets at FanDuel With a $5 Winning Wager

Chivas Guadalajara Preview

Gabriel Milito and his colleagues pulled off the difficult task, needing a minimum of a two-goal margin to get into the next phase of the liguilla. Chivas managed to cement the result they needed, beating Tigres two to nil over the weekend, advancing on the 3-3 aggregate thanks to finishing higher in the 2026 Clausura table. 

With a roster filled with pivotal role players and class, Chivas had to lean on the youngster and youth academy product Santiago Sandoval. The 18-year-old striker scored a pair of goals in three minutes, earning him player of the match honours. With Mexico’s national team preparation for the World Cup, it’s unclear if the El Tri starlet Armando González will see the pitch, as he’s been out of action since April 25, which saw him sit out for the two quarterfinal postseason fixtures. 

Bet $5 at FanDuel, Get $150 in Bonus Bets if Your Bet Wins

Cruz Azul vs. Chivas Guadalajara - My Pick

• Cruz Azul vs. Chivas Guadalajara pick: Cruz Azul moneyline three-way (+110) at FanDuel

Recent times have seen the Sacred Herd struggle to get their noses in front when playing away from home against Cruz Azul. Across all competitions, Chivas has only successfully gotten the better of Cruz Azul on three occasions from the previous 18 meetings. Even of late, La Máquina have dominated the opposition, winning six of the last seven skirmishes.

It can be argued that these two giants in Mexican soccer  constantly underperform in the biggest moments in Liga MX play, but we feel the hosts can get past Chivas on Wednesday. 

Win a $5 Wager at FanDuel, Get $150 in Bonus Bets

How to Watch Cruz Azul vs. Chivas Guadalajara

• When: May 13, 10pm ET  

• Where: Estadio Banorte

• TV: Univision Networks (Univision, UniMás, TUDN), CBS Sports, Fox Sports, NBC Universal, ViX, Peacock