Club America vs. Mazatlan F.C. Prediction: Defending Champs Look To Roll Into the Postseason on a High Note

• Club America suffered their third league defeat on Wednesday, dropping down to third place in the table

• Mazatlan F.C. saw their winless run extend to three, eliminating the club from playoff contention. 

Saturday evening Club America welcomes Mazatlan F.C. down to Estadio Ciudad de los Deportes to conclude their 2025 Clausura season. The most recent fixture between these two adversaries occurred in the previous term, which saw La Águilas wallop Mazatlan 5-0 on the road. 

Here, we will break down the betting odds and share our favourite picks for Club America vs. Mazatlan F.C.

Club America vs. Mazatlan F.C Betting Odds for Saturday, April 19

Saturday tilt sees the visiting side as the pegged favourites in the Asian Spread market. Club America -1.5 is priced at +105 while Mazatlan F.C. +1.5 is listed at -125.

Club America vs. Mazatlan F.C Odds

The following odds are taken from bet365 Sportsbook. Use our promo code WSN365 at bet365 to claim your bonus: Bet $5, Get $150 in Bonus Bets Win or Lose

Club America vs. Mazatlan F.C Betting Prediction

Club America Preview

Wednesday evening saw Club America’s poor run form continue as they suffered a 1-0 against C.F. Monterrey. With the setback, La Aguilas have failed to register a win in their previous five contests across all competitions. 

The club's leading goal contributor has been subpar in recent weeks failing to get onto the stat sheet. Alex Zendejas has now gone six straight Liga MX matches without tallying or setting up a goal for his teammate’s. Zendejas has cataloged five goals and four assists in 14 league appearances on the pitch. 

With the result of a compact schedule and being three-peat league winners, it’s taking a toll on this squad as the latest player to leave the match was Brian Rodriguez. The decorated Club America player exited the match six minutes from the opening whistle with his timetable to return is up in the air. In 13 Clausura outings in 2025, the 24-year-old has gathered four goals and three assists. 

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Mazatlan F.C Preview

Víctor Manuel Vucetich's men were dismantled on their own pitch Wednesday evening losing 2-0 against Club Tijuana. The Canoneros didn’t generate much on attack as they have now gone 10 of their last 11 matches without registering more than a goal when they take to the field. 

Between the sticks, it was an uneventful night for Hugo Gonzalez. Despite only facing three shots, the 34-year-old keeper conceded two goals. Starting all 16 games this year, Gonzalez has allowed 21 goals while possessing a 69.1 save percentage. 

Rodolfo Pizzaro has yet to open up his Mazatlan account since rejoining the top flight division last fall. Pizzaro is a well-traveled experienced midfielder with stints in Chivas, Monterrey and spending most of his time with Pachuca. In over 1000 minutes played in the 2025 season, Pizzaro has only acquired two shots on target.

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Club America vs. Mazatlan F.C - My Pick

• Club America vs. Mazatlan F.C pick: Club America -1.5 (+105) at bet365

Despite Club America suffering a rash of injuries, we feel that in this season finale clash they have what it takes to get the job done as they possess one of the deepest rosters in Liga MX. The visitors have only secured one road win in their seven away trips this year. Their away defence has held its own, only conceding 10 goals, but they have yet to face a juggernaut on enemy soil. With both teams participating in midweek affairs, it favours Club America as they are used to playing twice a week versus their counterparts, giving La Águilas the edge in game preparation.

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How to Watch Club America vs. Mazatlan F.C

• When: April 19, 7 p.m. ET

• Where: Estadio Ciudad de los Deportes

• TV: FOX Deportes, Univision, UniMas, Telemundo, Universo, TUDN, ESPN Deportes, ESPN+ and ViX+