Mazatlan F.C. vs. Atletico San Luis Prediction: Both Teams Hungry for a Decisive Outcome

• Mazatlan F.C. have yet to win a match in Liga MX since July 18

• Atletico San Luis currently sits three points out of the play-in round position 

Friday evening, Atletico San Luis will clash against Mazatlan F.C. at Estadio de Mazatlan. The preceding campaign was the last time these two met, which saw San Luis come out on top in a 2-1 win on their home pitch. 

Here, we will break down the betting odds and share our favourite picks for Mazatlan F.C. vs. Atletico San Luis.

Mazatlan F.C. vs. Atletico San Luis Betting Odds for Friday, October 3

The book senses both keepers will be breached with the displayed odds. Both teams to score are listed at -150, while both clubs failing to achieve a goal is priced at +110.

Mazatlan F.C. vs. Atletico San Luis Odds

The odds for Mazatlan F.C. vs. Atletico San Luis can be found in the odds table below, courtesy of bet365 sportsbook. Sign up for a bet365 account with our promo code WSN365 and claim the welcome offer: Bet $5, Get $200 in Bonus Bets Win or Lose.

Mazatlan F.C. vs. Atletico San Luis Betting Prediction

Mazatlan F.C. Preview

The misery continued over the weekend as Robert Siboldi’s men failed to enter the win column in nine straight Liga MX matches. The winless drought was extended when they squared off against the defending champions, Toluca. Saturday’s result saw the Red Devils secure a 3-1 victory, dropping the Cañoneros down to 16th place. 

So far throughout the 2025 Apertura, Mazatlan hasn’t lit up the scoreboard frequently, but has had steady contributions from their squad. Nicolás Benedetti is this term's clubhouse leader in the goals department with three, which saw him garner a tally on Saturday, ending a six-game goalless drought. Behind Benedetti, the Canoneros have a trio of players who have obtained a pair of goals.

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Atletico San Luis Preview

Over the weekend, Guille Abascal’s troops suffered their second consecutive setback, dropping all three points on the road against C.F. Pachuca. Inside the 90-minute frame, Atletico San Luis outpossessed their counterpart but failed to use their possession to good use, finishing with an xG of 0.99. 

Joao Pedro has stalled since recording a pair of goals against Santos on September 21. He has failed to hit the back of the net in his two previous outings and is sitting with eight goals this season. The 33-year-old striker should get his opportunity to feature on the scorers’ sheet as he is averaging 1.59 shots on target per 90 minutes, placing him as one of the league's most effective strikers across the competitions.

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Mazatlan F.C. vs. Atletico San Luis - My Pick

• Mazatlan F.C. vs. Atletico San Luis pick: Both teams to score yes (-150) at bet365

Entering this affair, the Apertura campaign sees an average of both teams scoring in 55 percent of the games. Both opponents in this contest are well above the league average, as Mazatlan has seen 73 percent of their tilts have featured both clubs scoring, while San Luis is at 64 percent. Regardless of the table position the two sets of teams find themselves in, they are still avoiding being blanked in Liga MX play. The host has only failed to get on the scoreboard on three occasions; the visitors have only been excluded from the stat sheet twice. We feel that with these solid backings, both clubs should find a way to score a goal on each other.

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How to Watch Mazatlan F.C. vs. Atletico San Luis

• When: October 3, 10 p.m. ET

• Where: Estadio de Mazatlan

• TV: Univision, UniMás, TUDN, DirecTV Stream