Tigres UANL vs. Toluca Prediction: Red Devils Look To Carry Momentum in Semi-Final Leg 1

• Despite reaching the final four, Tigres UANL have yet to win a postseason match in 2025

• After losing the first leg during their quarter-finals clash, Toluca answered back with a win to punch their ticket into the next round

Wednesday evening will see Toluca make its way down to Estadio Universitario to battle against Tigres UANL. Their most recent encounter occurred back in February, which saw Toluca secure a one-goal clean sheet victory on their home turf, which saw Paulinho nab a late tally in extra time. 

Here, we will break down the betting odds and share our favourite picks for Tigres UANL vs. Toluca.

Tigres UANL vs. Toluca Betting Odds for Wednesday, May 14

The double chance market has pegged either side winning as the most likely scenario, with the fabricated odds sitting at -300. For the hosts to win or draw is priced at -275, while Toluca is listed at -150 for the same outcome.

Tigres UANL vs. Toluca Odds

The following odds are taken from bet365 Sportsbook. Use our promo code WSN365 at bet365 to claim your bonus: Bet $5, Get $150 in Bonus Bets Win or Lose

Tigres UANL vs. Toluca Betting Prediction

Tigres UANL Preview

Guido Pizarro’s men had luck on their side Sunday evening, as they were in the final moments of their season concluding when Necaxa surrendered an own goal, gifting Tigres UANL a spot in the semis. The 2-2 draw saw both sides going all out on attack, with Tigres outshooting their counterparts 21 to 18 inside the 90 minutes. 

Tigres’ lone goal scorer, Juan Brunetta, finished as the game's Player of the Match with superb play on Sunday. The 28-year-old midfielder cataloged six total shots and completed the most successful dribbles with three. Between the regular and playoff phases in 2025, Brunetta has hit the back of the net on seven occasions while adding three assists. 

Now listed day to day, Tigres could get a welcome boost on attack with André-Pierre Gignac getting close to returning to action. The star French striker hasn’t played since February 25th when he suffered a leg injury. Since arriving in Mexico in 2015, Gignac has scored 219 goals in 407 appearances across all competitions. 

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Toluca Preview

Suffering a scare in the first leg, Antonio Mohamed’s troops responded with a 2-1 victory over C.F. Monterrey, advancing on aggregate with a 4-4 scoreline. It was a difficult task for Toluca to walk away with a maximum result, as Antonio Briseno was shown a red card in the 32nd minute. 

The star of the squad came up with a momentous moment in the 68th minute as Paulinho bagged the game-winning goal to send Toluca into the next phase. The Portuguese international finished this campaign tied in the regular season golden boot race with 12. All Paulinho has done since joining Toluca the previous summer has been breaching the opposing keeper. Through 39 competitive matches, the striker has accumulated 27 goals. 

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Tigres UANL vs. Toluca - My Pick

• Tigres UANL vs. Toluca pick: Toluca double chance (-150) at bet365

Entering this tilt, the last 36 affairs between these two, Toluca possesses the slight edge, winning in 16 instances versus Tigres’ 11. The draw has transpired in nine junctures, with the last one materializing in October of 2023, a span of three matches. The Estadio Universitario has been kind to Tigres in this 2025 Clausura, winning eight out of nine home dates. 

That said, we feel Toluca can hang around in this skirmish as they are a quality opponent themselves, finishing up the regular season with the most points. Between multiple tournaments, Tigres are winless in their last four. Toluca are the better team in form currently and aren't shy about getting into the scoresheet on the road, scoring a league high 20. We feel Toluca has a decent shot at avoiding a defeat in this first leg. 

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How to Watch Tigres UANL vs. Toluca

• When: May 14, 11 p.m. ET

• Where: Estadio Universitario

• TV: FOX Deportes, Univision, UniMas, Telemundo, Universo, TUDN, ESPN Deportes, ESPN+ and Vix+