Inter Miami CF vs. Orlando City SC Prediction: First Floridian Derby at Herons New Home

Saturday evening, we get our first installment of the Florida derby, which sees Orlando make the short jaunt to Nu Stadium to clash with Messi and Co. These two sides met in March, when the Herons doubled up on their adversary in a 4-2 thrashing. 

• Inter Miami CF are unbeaten in their last 11 across all competitions 

• Orlando City SC currently sit in 14th place in the MLS’ Eastern Conference 

Here, we will break down the betting odds and share our favourite picks for Inter Miami CF vs. Orlando City SC.

Inter Miami CF vs. Orlando City SC Betting Odds for Saturday, May 2

The oddsmakers sense this skirmish could feature an ample number of goals, as evidenced by the displayed odds. Over 3.5 goals is priced at -130 while the under is listed at +102.

Inter Miami CF vs. Orlando City SC Odds

The odds for Inter Miami CF vs. Orlando City SC in this article are taken from FanDuel Sportsbook. Sign up for a FanDuel account and claim your welcome offer: Bet $5, Get $250 in Bonus Bets.

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Inter Miami CF vs. Orlando City SC Betting Prediction

Inter Miami CF Preview

Guillermo Hoyos and his men continue to catalogue results, as the interim manager has now gone three matches unbeaten under his tenure. Over the weekend, the Herons faced a surging New England Revolution side, which ended in a 1-1 draw. Despite avoiding a defeat, Miami felt they got shortchanged a bit, as they dominated possession with 62 percent while finishing with an xG of 2.71, compared to the Revs' xG of 1.58. 

Since the conclusion of the March international break, newcomer Germán Berterame has been the standout member. After tallying last Saturday, the ex-C.F. Monterrey superstar has now amassed five goal contributions in as many games. For the second consecutive outing, Lionel Messi was held off the scorers’ sheet, which has seen him dip downwards in the Golden Boot chase. The 2022 FIFA World Cup winner has scored seven goals through nine appearances, putting the Argentine two goals back in the co-lead in MLS.

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Orlando City SC Preview

So far, 2026 has been a turbulent campaign for Martín Perelman’s crew. Heading into the 11th week of the MLS calendar, Orlando sits two points ahead of last-place Philadelphia Union. Their most recent fixture saw the Lions 10 minutes out from nabbing all three points but squandered their one-goal lead, dropping their result to D.C. United, losing 3-2. 

One of the big factors for Orlando’s struggles is its inability to keep the ball out of its own net. Currently, the club has the worst goals-against average in MLS, conceding an average of 2.90 goals per game. All the blame can’t fall solely on Maxime Crépeau between the sticks, as he’s conceded 23 goals, but his expected goals on target sits at 21.9. Thanks to their defensive mishaps, the club has yet to tally a clean sheet in league play. 

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Inter Miami CF vs. Orlando City SC - My Pick

• Inter Miami CF vs. Orlando City SC pick: Over 3.5 goals (-130) at FanDuel

Orlando has been struggling with individual errors and a lack of structure, no matter who’s managing on the touchline. When Orlando plays away from home, they get exposed, having conceded 20 goals. Brushing up against an offensive juggernaut like Inter Miami should raise some red flags for the visitors. Orlando City have also participated in six of the 10 fixtures that featured four or more goals.

Inter Miami have yet to replicate the dominant displays we’ve seen in the Messi era at their old digs, remaining winless through three outings at the newly opened Nu Stadium. When these two Florida rivals encounter each other, they have produced some barn burners on the scoreboard, with five of the previous seven meetings ending with four or more goals, which is why we are backing the total to surpass the 3.5 goal mark.

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How to Watch Inter Miami CF vs. Orlando City SC

• When: May 2, 7 p.m. ET

• Where: Nu Stadium

• TV: Apple TV