San Jose Earthquakes vs. Orlando City SC Prediction: Expect Goals To Be Tallied

Wednesday evening, a full slate of MLS action returns from the completion of the 2026 FIFA World Cup. Wrapping up round 16 of the league calendar will see Orlando travel cross-country to PayPal Park to take on the San Jose Earthquakes.

• San Jose currently occupy second place in the Western Conference with 32 points

• Orlando City SC has lost nine of the 15 league matches they have played

Here, we will break down the betting odds and share our favourite picks for San Jose Earthquakes vs. Orlando City SC.

San Jose Earthquakes vs. Orlando City SC Betting Odds for Wednesday, July 22

The oddsmakers sense goals will be scored, based on the manufactured odds that are available. Over 3.5 goals is listed at -130 while the under is priced at +102.

San Jose Earthquakes vs. Orlando City SC Odds

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San Jose Earthquakes vs. Orlando City SC Betting Prediction

In seven all-time meetings, the hosts in Wednesday’s fixture have only beaten Orlando once. Now it's time to identify where the best betting value lies and reveal our top picks.

San Jose Earthquakes Preview

Bruce Arena's second season on the Quakes' touchline has seen the benefits of his tactical approach finally come to fruition. San Jose has enjoyed a strong 2026 campaign so far, sitting third overall in the Supporters’ Shield race, winning 10 of the 15 MLS matches they have played, giving them one of their best starts to a season in years.

The Earthquakes are racking up the goals all without the service of their offseason marquee acquisition, Timo Werner. The absence of the consistent double-digit goal-getter in the Bundesliga, was perceived to be a big blow to the offence, but San Jose has a new leader on attack. Preston Judd has made a name for himself, amassing 11 goals in 15 outings, placing him 4th overall in MLS’ Golden Boot chase.

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Orlando City SC Preview

Despite the awful start to the campaign, Martín Perelman is still in charge as the manager, hoping the pause in the MLS calendar will give his men time to reset and turn things around. The Lions aren’t fully out of the playoff picture, trailing the last position by four points, but their inconsistent play has prevented them from closing the gap.

Now that he was officially unveiled as the team’s newest Designated Player, Antoine Griezmann should help bolster the scoring output. The 2018 FIFA World Cup winner with France still has plenty of class left in the tank and can thrive in his anchor role, where he seems to be at his best. In his last season in La Liga with Atlético Madrid, he tallied seven goals and four assists.

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San Jose Earthquakes vs. Orlando City SC - My Pick

• San Jose Earthquakes vs. Orlando City SC pick: Over 3.5 goals (-130) at FanDuel

We suspect the World Cup break will have no bearing on how explosive the Earthquakes offence can be, as they are averaging 2.30 goals per match. Orlando adding Griezmann only increases the likelihood of goals from the visitors. The Lions already possess lethal talent with Martín Ojeda, 11 goals scored, and Marco Pašalić, a play-making specialist. Both sides have struggled to keep the ball out of their own net, as both counterparts haven’t kept a clean sheet in 10 straight contests.

For the visitors, they are averaging 2.90 goals conceded per match, increasing the scenario of goals filling out the scoresheet.

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San Jose Earthquakes vs. Orlando City SC

• When: July 22, 10.30 pm ET 

• Where: PayPal Park 

• TV: Apple TV