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Best MLB Home Run Predictions Today: The Drought Ends for Shohei Ohtani

Published: May 12, 2026, 09:00 AM ET
5 min read

It goes without saying that picking home run props with just six games on the schedule isn’t easy. But we’ll get another chance to start our week strong on Tuesday. Leading the way will be Shohei Ohtani, who is in the midst of an unusual home run drought. But today could be Ohtani’s day to get back to hitting home runs, and he’s one of the players we’re banking on to homer on Tuesday.

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Best Home Run Predictions for Tuesday, May 12

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Best Home Run Predictions TodayFanDuelKalshi to Win
Shohei Ohtani Anytime Home Run+172Los Angeles Dodgers 71%
Elly De La Cruz Anytime Home Run+320Cincinnati Reds 56%
Oneil Cruz Anytime Home Run+330Pittsburgh Pirates 73%
Jo Adell Anytime Home Run+570Los Angeles Angels 45%
Odds and market prices are accurate as of the time of publishing and subject to change before the event.

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Best MLB Home Run Predictions Today 2026 05 12 Dodgers Shohei Ohtani

Home Run Picks for Tuesday, May 12

There are some fantastic home run props out there today, but some stand above the rest. Below are the three players we’re locked in on. 

Shohei Ohtani Anytime Home Run (+172) at FanDuel Sportsbook

Ohtani hasn’t hit a home run since April 26, giving him just six home runs this season. That’s a shocking total for a player who is usually among the league leaders in home runs. Even more shocking, Ohtani is hitting just .111 in May and is down to .233 on the season.

But Tuesday could finally be the day that Ohtani gets out of his slump when facing Adrian Houser and the Giants. While he has just three career at-bats against Houser, Ohtani has two hits, including a home run. Houser, meanwhile, has an ERA of 6.19 and has given up at least one home run in five straight starts. Left-handed hitters have a .747 slugging percentage against Houser this year, which is the biggest reason to believe Ohtani can do damage against him.

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Elly De La Cruz Anytime Home Run (+320) at FanDuel Sportsbook

Miles Mikolas starts on Tuesday, and that means we have to target someone on the Reds to go deep. Mikolas owns a 7.44 ERA this year, giving up nine home runs, with only five other pitchers giving up more homers this year. We chose De La Cruz, who is 5 for 15 with a couple of extra-base hits in his career against Mikolas.

The pitching matchup aside, De La Cruz is swinging a hot bat right now. He has three consecutive multi-hit games and is 8 for 17 over his last four games. While De La Cruz is yet to hit a home run in May, he still has 10 home runs on the season, so there’s no doubt he has the power to take advantage of a pitcher like Mikolas.

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Oneil Cruz Anytime Home Run (+330) at FanDuel Sportsbook

Cruz slumped during the early part of May, but it looks like he’s coming around, so now is a good time to strike while the iron is hot. He went 5 for 14 over the weekend, including a home run on Sunday, giving him 10 on the season. Cruz homered in back-to-back games earlier this season, so if he’s heating up, he has a chance to do so again.

The caveat is that Cruz has never faced Michael Lorenzen, who starts for the Rockies in Pittsburgh on Tuesday. Lorenzen is another pitcher who’s been dreadful this season, giving up seven home runs and posting a 6.92 ERA. Left-handed hitters are batting .427 against him and are responsible for six of the seven home runs Lorenzen has given up, making Cruz Pittsburgh’s best option to go deep.

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Jo Adell Anytime Home Run (+570) at FanDuel Sportsbook

It was surprising to find Adell with such lucrative home run odds for Tuesday. While he only has six home runs on the season, his bat is coming alive. Adell has three multi-hit games in his last four games, going 7 for 14 over that stretch, including three doubles and a two-homer game on Sunday.

On Tuesday, Adell and the Angels face Cleveland’s Slade Cecconi. While he has just three career at-bats against Cecconi, two of those at-bats were home runs. While that’s obviously a small sample size, Cecconi has also given up eight home runs this year, most of which were hit by right-handed hitters. He’s been vulnerable to the long ball, while Adell is heating up, making this a favorable matchup.

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Bryan Zarpentine WSN Contributor

Bryan Zarpentine

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Bryan Zarpentine is a 2008 graduate of Syracuse University and has been working as a freelance writer and editor since 2010. During that time, he has contributed to countless sites while covering baseball, soccer, the NFL, college football, and college basketball.
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