Best NRFI Bets Today: Expect Suarez to Neutralize the Yankees Top of Their Order

With the New York Yankees residing near the bottom of the board in Contact Rate, expect their struggles at the plate to continue to persist as they face off against Ranger Suarez and an outfield who excels in coverage. Later in the night, we turn our attention towards the Chicago White Sox and Arizona Diamondbacks with a pair of efficient arms battling it out against two underwhelming lineups.

Looking for more MLB betting insights? Check our selection of the Best MLB Home Run Props Today.

Best NRFI Bets for Wednesday, April 22

Odds are provided by BetMGM Sportsbook, one of the best US sportsbooks. Sign up today and use BetMGM bonus code WSNSPORTS and you'll be eligible for the following welcome offer: Get Up to $1,500 in Bonus Bets.

*21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.

If you are in a state where BetMGM Sportsbook is not yet legal, we recommend trying Kalshi, one of the best prediction markets in the US. Sign up using Kalshi promo code WSN to get a $10 bonus after making 100 contracts.

New York Yankees vs. Boston Red Sox - Max Fried vs. Ranger Suarez (6:45 PM, EST)

Expect no runs to be scored in the first inning between the New York Yankees and Boston Red Sox with a pair of dominant arms set to take the mound.

Under 0.5 Run (-135) at BetMGM Sportsbook

Since the start of the regular season, the New York Yankees have been unable to string together their Hits, ranking well below league average in Contact Rate. Their inconsistencies at the plate leaves them vulnerable to falling into prolonged scoring lulls, forcing them to play in highly volatile contests.

In a AL East divisional matchup against the Boston Red Sox, expect the Yankees to continue to underwhelm as they face off against Ranger Suarez who is averaging an ERA of 3.22 and WHIP of 1.075. Especially with his back end narrowing the width of their gaps in the outfield, surrounding Suarez with a group who ranks in the top-12 in Defensive Efficiency. This pitching dominance could significantly shift the AL East odds as the season progression puts the Yankees' early lead at risk.

Locked into a pitchers duel with Suarez is Max Fried, a contender for the AL Cy Young award who is averaging an ERA of 2.97, a FIP of 3.04, and a WHIP of 0.810. With the Red Sox also grading out poorly in Hit Rate and in OPS, expect Fried to continue to put them in low quality contact scenarios and escape the first inning without giving up a Run. Given his consistency and dominance, his AL Cy Young odds continue to trend in a favorable direction among bettors and analysts alike.

Join BetMGM Sportsbook Today

Chicago White Sox vs. Arizona Diamondbacks - Anthony Kay vs. Eduardo Rodriguez (9:40 PM, EST)

With Eduardo Rodriguez on the mound, the Chicago White Sox’s struggles on offense will be on full display, resulting in a quick exit in the first inning.

Under 0.5 Run (-110) at BetMGM Sportsbook

In his first four starts, Eduardo Rodriguez has been able to keep opposing runners out of scoring position, kicking off his 2026 campaign with an ERA of 1.96. While his low Strikeout Rate is alarming, Rodriguez is able to mask it by averaging less than one Hit Against per Inning Pitched.

In a favorable matchup against the Chicago White Sox, expect Rodriguez to build on his momentum by taking advantage of an offense who ranks in the bottom ten in Hit Rate and in On Base Percentage. With the White Sox suffering a drop off production throughout their lineup, they will be unable to advance their runners, making them prone to being left stranded after the third out.

On the other side of the field, Anthony Kay is expected to get the start for the White Sox, bringing with him a rocket arm who averages an ERA of 2.30 while supported by a defense who ranks above league average in Adjusted Defensive Rating. With Kay exploiting the Diamondbacks low Contact Rate while attacking the strikezone, expect the White Sox pitcher to keep a clean sheet in the first inning.

Get Your BetMGM Bonus Code

Best YRFI Bets Today

• Los Angeles Dodgers vs. San Francisco Giants - Shohei Ohtani vs. Tyler Mahle - With Tyler Mahle on the mound, the Los Angeles Dodgers will be able to light up the scoreboard from the opening pitch as the San Francisco Giants pitcher is averaging an ERA of 7.23 and nearly two runners on base per inning.

• Minnesota Twins vs. New York Mets - Simeon Woods Richardson vs. Clay Holmes - Expect the New York Mets to break out of their slump against the Minnesota Twins, battling it out against Simeon Woods Richardson who averages more than one Hit Against and less than one Strikeout per Inning Pitched.

Make Your Bet at BetMGM