When you sign-up through links on our site, we may earn an affiliate commission. Learn more >

Best MLB Prop Bets Today: Hitters to Favor and Pitchers to Fade

Written by: Bryan Zarpentine
Published May 22, 2024
4 min read
Best MLB Prop Bets 2024 05 22

With four wins out of five picks on Tuesday, we’re heating up in late May. We've turned a profit on both days this week and we're looking to do the same on Wednesday. The plan is to stay aggressive with prop bets that have plus odds and good value. Here are the picks we have made on Wednesday with odds from DraftKings Sportsbook, which is offering new users a no-sweat bet of up to $1,500.

Bet on MLB Player Props at DraftKings

🔥 Claimed by 130 people this week!



Get a No Sweat First Bet up to $1,500 in Bonus Bets

21+ | T&Cs apply

Best MLB Prop Bets Today: Angels vs. Astros (2:10 PM, EST)

Kyle Tucker Over 1.5 Total Bases (+105) at DraftKings

Tucker continues to lead the majors in home runs after hitting four in his last three games. He also has at least one hit in 11 of his last 12 games, including four multi-hit games. In those 12 games, Tucker has gone over 1.5 bases eight times, so as long as he still has plus odds, there is good value here. The kicker is that he and several other Astros have crushed Tyler Anderson of the Angels. Tucker is 7 for 9 with four extra-base hits in his career against Anderson. Even in less than 10 at-bats, that’s an insane amount of production, so we’re all-in on Tucker in Wednesday’s game.

Bet on Angels vs Astros Props at DraftKings 

Best MLB Prop Bets Today: Brewers vs. Marlins (6:40 PM, EST)

Sal Frelick Over 0.5 Runs (+215) at DraftKings

The average fan may not know Frelick, but he’s had quite a week. The young outfielder has scored a run in five straight games, and we love the odds of him scoring another run on Wednesday. In his last six games, Frelick has reached base 11 times, so he’s giving his teammates plenty of opportunities to drive him in. Frelick is also 3 for 5 in his career against Miami starter Jesus Luzardo, so we’re expecting him to get on base in this game. We also think the Brew Crew will score plenty of runs against Luzardo and his 5.02 ERA. 

Bet on Brewers vs Marllins Props at DraftKings 

Best MLB Prop Bets Today: Braves vs. Cubs (7:40 PM, EST)

Justin Steele Over 2.5 ER (-140) at DraftKings

Steele missed all of April with an injury and has had a disappointing start in May. He’s conceded 10 earned runs on 12 hits across his last two starts, in part because he’s given up five home runs. While he’s capable of pitching much better, the Braves are not the team he wants to face right now. Not only is the Atlanta lineup dangerous but Steele also has dreadful numbers against several key hitters. While he’s dominated Marcell Ozuna and Austin Riley, the quartet of Ronald Acuna Jr., Ozzie Albies, Michael Harris, and Matt Olson is a combined 14 for 28 with five extra-base hits. That makes us think it’ll be another rough outing for Steele.

Ozzie Albies Over 2.5 Hits + Runs + RBI (+115) at DraftKings

Albies has outstanding numbers against Steele, going 4 for 6 with a pair of doubles against the lefty. The switch-hitter is batting .353 with an OPS of .912 against lefties this year, so he’s far better from the right side of the plate. Keep in mind that Albies tends to have RBI chances by virtue of hitting behind Acuna while also scoring runs frequently with Ozuna and Olson behind him. Given the favorable matchup against Steele, this is the perfect time to target Albies with this bet.

Bet on Braves vs Cubs Props at DraftKings 

Best MLB Prop Bets Today: Diamondbacks vs. Dodgers (10:10 PM, EST)

Tyler Glasnow Under 7.5 Strikeouts (+120) at DraftKings

Glasnow currently leads the majors in strikeouts and has gone over 7.5 strikeouts in five straight starts. But with such a big number and plus odds, we're going to take the under for this bet. The biggest reason is that the Diamondbacks are hard to strike out, averaging just 7.7 strikeouts per game. As good as Glasnow is, we don't expect him to go the distance against an Arizona lineup that beat the Dodgers on Tuesday, making it hard for him to reach at least eight strikeouts.

Bet on Diamondbacks vs Dodgers Props at DraftKings 


Responsible Gambling

If you or someone you know needs support or wants to speak with a professional about responsible gambling, seek out the correct resources. Call or text 1-800-GAMBLER to get help, or visit 1800gambler.net for more information. WSN is an advocate for safe gambling practices. Visit our Responsible Gambling Center for more details.

Image for Bryan Zarpentine

Bryan Zarpentine

Sports Betting Analyst & Content Specialist

Online Sports Betting
Bryan Zarpentine is a 2008 graduate of Syracuse University and has been working as a freelance writer and editor since 2010. During that time, he has contributed to countless sites while covering baseball, soccer, the NFL, college football, and college basketball.
Nationality: American
Education: Bachelor of Arts
Favourite Sportsbook: BetMGM Sportsbook
Favourite Casino: BetMGM Casino
14 years
We've been featured on:
espn logo
reuters logo
cbs-news logo
forbes logo
entrepreneur logo
entrepreneur logo
We only list licensed sportsbooks

© Rebel Penguin ApS 2024 (a subsidiary of Gaming Innovation Group Inc.)

We support responsible gambling. 21+ Only. Gambling problem? Call 1-800-Gambler.

WSN.com is run by iGaming Cloud Inc (a Gaming Innovation Group Subsidiary) and is registered with the New Jersey Division of Gaming Enforcement (DGE) under affiliate vendor ID 89744, with the Indiana Gaming Commission (IGC) under certificate of registration number SWR-000148, approved by the Pennsylvania Gaming Control Board as a gaming service provider, under certificate registration number 117656-1, possesses a Vendor Minor sports betting license from the Colorado Limited Gaming Control Commission (account number 94414163), granted a vendor registration number VR007603-20-001 by the Michigan Gaming Control Board, an interim Sports Wagering Supplier license, under license number SWS 066, issued by the West Virginia Lottery Commission, a sports betting vendor registration, under registration number #100400, issued by the Director of Gaming Licensing and Investigations of the Virginia Lottery to operate in the State of Virginia, and a Vendor Registration issued by the Sports Wagering Committee of the Tennessee Education Lottery Corporation.

Advertising disclosure: WSN contains links to online retailers on its website. When people click on our affiliate links and make purchases, WSN earns a commission from our partners, including ESPN and various sportsbooks.