When you sign-up through links on our site, we may earn an affiliate commission. Learn more >

Best MLB Parlay Picks Today: Opening Day is Finally Here

Written by: Tanner Kern
7 min read

Baseball is back, so it’s time for an MLB parlay. Baseball can be one of the most lucrative sports for parlay betting because there are countless markets to choose from on top sportsbooks such as DraftKings. 

DraftKings Sportsbook offers new customers $150 in bonus bets instantly when they wager $5 on the platform.

Here, we will break down our three-leg parlay with +316 odds.

🔥 Claimed by 101 people this week!



Bet $5, Get $200 in Bonus Bets Instantly

21+ | T&Cs apply

Best MLB Parlay Picks Today 03 28 2024

MLB Parlay Picks Today: Angels vs. Orioles (3:05 PM, EST)

Orioles Moneyline (-192) at DraftKings

The Orioles won the American League East last season, and they’re picked second to repeat in 2023. Check out our weekly divisional breakdown if you want some AL East futures.

Baltimore signed former Cy Young winner Corbin Burnes in the offseason, and he will pitch on Opening Day. Burnes is one of the most dominant pitchers in the game, coming from the National League.

National League hitters were starting to adjust to Burnes, so the change of scenery should benefit the wing. Burnes was 10-8 with a 3.39 ERA and a 1.07 WHIP in 2023.

He kept the bases cleaner than many pitchers in baseball, ranking fifth in WHIP. He will pitch against Patrick Sandoval, one of the weaker Opening Day starters.

Sandoval was 7-13 with a 4.11 ERA and a 1.51 WHIP in 2024. We expect the Orioles' young crew of hitters like Adley Rutschman, Ryan Mountcastle, and Gunnar Henderson to jump on Sandoval early at home.

Create your Parlay Pick at DraftKings CTA icon

MLB Parlay Picks Today: Cardinals vs. Dodgers (4:10 PM, EST)

Dodgers Moneyline (-230) at DraftKings

The Los Angeles Dodgers will be a heavy favorite in every game they play. They’ll be viable parlay pieces throughout the season, and we trust them on Opening Day.

Los Angeles split their opening series in Korea against the Padres. They have an advantage on Opening Day because they have already played competitive baseball this year.

Tyler Glasnow will pitch for Los Angeles and posted substantial numbers at the start of the year, considering he wasn’t ready. Glasnow went five innings against San Diego and recorded three strikeouts with two earned runs.

He will throw against Miles Mikolas, and the Los Angeles offense should shred the wing. Mikolas was 9-13 with a 4.78 ERA and a 1.32 WHIP in 2023. Los Angeles has one of the biggest payrolls in baseball, and it should show up against a rebuilding Cardinals team.

Claim your DraftKings promo offer CTA icon

MLB Parlay Picks Today: Giants vs. Padres (4:10 PM, EST)

Under 7.5 (-110) at DraftKings

The Giants and Padres both have viable offenses. San Francisco made a lot of noise in the offseason, adding Matt Chapman from the Blue Jays. Chapman is coming off a down season, but he is a tremendous hitter who can get hot quickly.

The Padres have underperformed with their current roster, but Manny Machado and Fernando Tatis Jr. are two of the scariest hitters in the game. Yet, we’re still playing the under of 7.5 runs in this contest. 

Yu Darvish will throw against Logan Webb. Darvish is a liability in this contest, but he is still one of the more reputable pitchers in the game.

Darvish looked strong against the Dodgers in his first start of the year and should be even better against the Giants. Webb has owned the Padres throughout his career, and very few San Diego hitters have gotten the best of the pitcher. 

The Padres are batting a combined .237 off Webb in his career with just a .283 OBP. The pitcher has only surrendered one homer to San Diego’s batters over his career.

If these pitchers throw how they’re capable, this game should stay under the 7.5 run total.

Join DraftKings today CTA icon

More MLB Best Bets Today

Image for Tanner Kern


Tanner Kern

345 Articles

Tanner Kern has been working in the betting industry since 2020. He currently is a social media content creator at DraftKings and contributes to multiple sites in addition to WSN, including Forbes and VSiN. He is also the cohost of the podcast Ride the Line at WSN.

More info on Tanner Kern
We've been featured on:
espn logo
reuters logo
cbs-news logo
forbes logo
entrepreneur logo
entrepreneur logo
We only list licensed sportsbooks

© Rebel Penguin ApS 2024 (a subsidiary of Gaming Innovation Group Inc.)

We support responsible gambling. 21+ Only. Gambling problem? Call 1-800-Gambler.

WSN.com is run by iGaming Cloud Inc (a Gaming Innovation Group Subsidiary) and is registered with the New Jersey Division of Gaming Enforcement (DGE) under affiliate vendor ID 89744, with the Indiana Gaming Commission (IGC) under certificate of registration number SWR-000148, approved by the Pennsylvania Gaming Control Board as a gaming service provider, under certificate registration number 117656-1, possesses a Vendor Minor sports betting license from the Colorado Limited Gaming Control Commission (account number 94414163), granted a vendor registration number VR007603-20-001 by the Michigan Gaming Control Board, an interim Sports Wagering Supplier license, under license number SWS 066, issued by the West Virginia Lottery Commission, a sports betting vendor registration, under registration number #100400, issued by the Director of Gaming Licensing and Investigations of the Virginia Lottery to operate in the State of Virginia, and a Vendor Registration issued by the Sports Wagering Committee of the Tennessee Education Lottery Corporation.

Advertising disclosure: WSN contains links to online retailers on its website. When people click on our affiliate links and make purchases, WSN earns a commission from our partners, including ESPN and various sportsbooks.