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New England Patriots vs Cleveland Browns Predictions, Picks, Betting Odds Week 6

Written by: Mike Lukas
Updated October 14, 2022
16 min read
  • New England has a rookie under center, Bailey Zappe until Mac Jones is healthy
  • The Cleveland Browns run defense has been porous and their major weakness
  • Watch Patriots vs Browns live on Sunday, October 16, 2022, at 1:00 PM ET on CBS

Patriots vs Browns Week 6 Odds

Point Spread odds are provided by DraftKings. Get a $1,000 deposit bonus when you sign up at DraftKings.

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Money line odds are provided by Unibet. Sign up and get a $250 Risk-Free bet.

Patriots vs Browns Odds Point Spread Points Total Money Line
New England Patriots +3.0 (-115)
O42.5 (-110)
Cleveland Browns -3.0 (-105)
U42.5 (-110)

Patriots vs Browns Week 6 Picks

POINT SPREAD: Cleveland Browns -3 (-105)  at DraftKings

POINTS TOTAL: Over 42.5 (-110) at BetRivers

MONEY LINE: Cleveland Browns (-155) at Unibet

Patriots Vs Browns Bailey Zappe

Point Spread: Cleveland Browns -3 (-105) at DraftKings

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It looks like New England Patriots starting QB Mac Jones (ankle) is still listed as questionable for Week 6 but some insiders are saying he remains a “logical possibility” under center for HC Bill Belichick’s offense, but should he remain out his backup, Bailey Zappe, the former Western Kentucky standout, can also ball.

Zappe posted his first win as an NFL pro last week as the starter over the Detroit Lions, 29-0, a game in which he completed almost 81% of his passes going 17 for 21 with a TD and no interceptions, though in Week 6 against the Browns and their porous run defense chances are the Pats’ 9th ranked rushing attack will be featured in OC Matt Patricia’s offensive game plan.

That Browns run defense was weak against the LA Chargers last week allowing them to earn 238 yards on the ground in that loss, and the week prior Cleveland’s D let the Atlanta Falcons run over just over 200 yards, a schematic flaw stemming from a communication breakdown that Cleveland DC Joe Woods must address or else those calls for his job might be taken seriously.

Points Total: Over 42.5 (-110) at BetRivers



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At the start of the season, NFL insiders figured the Cleveland Browns would have a serviceable offense at best given it would be run by backup QB Jacoby Brissett during the eleven games that starter Deshaun Watson has been suspended but instead Brissett has delivered a fourth-ranked offense that scores 26.6 points per game.

New England, on the other hand, has a 17th-ranked offense that has generated 20.6 points per game this season and that total between the two of them – 52.2 – is well above what the oddsmakers are allowing for this bet, so take the over if you think that both of these teams will produce normally, with Pats fans needing to check in at game time to see if QB Jones will play.

Before you place any wagers on the NFL, make sure to check the injury reports of both teams since it is such a brutal league and you never know which playmakers will be suiting up, and in Week 6 the Browns are listing CB Denzel Ward (concussion) as questionable to play and for New England it’s QB Mac Jones, TE Jonnu Smith (ankle) and DE Lawrence Guy (shoulder).

Money Line: Cleveland Browns (-155) at Unibet

When you look at the Cleveland Browns roster, the talent is there so their 2-3 record must come down to failed coaching and execution, a challenge many teams faced this year with such a limited preseason for players to knock off the rust and for rookies like Browns PK Cade York to get safe opportunities to make plays.

York was a 4th round draft pick so Cleveland’s front office is expecting him to make big kicks like he did to win the game in Week 1, but his missed PATs and field goals in subsequent matchups are a reminder that he is still just a league newbie and should not be counted on to win games yet, though given how superior the Browns are on offense, take them to beat the Pats outright.

It’s a home game for Cleveland – an advantage at FirstEnergy Stadium where the noise in the Dawg Pound is deafening – and the weather there could be a factor since they are playing in an open arena next to breezy Lake Erie, a fall game that could still get chilly so be sure to check the weather on game day as these two teams try to break their all-time 13-13 tie for victories.

How to Watch Patriots vs Browns

  • What: New England Patriots vs Cleveland Browns
  • Where: FirstEnergy Stadium in Cleveland, OH
  • When: Sunday, October 16, 2022, at 1:00 PM ET
  • How: CBS
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Mike Lukas

1204 Articles

Mike Lukas is a retired standup comedian turned freelance writer now living in Dallas, Texas, originally from Cleveland, Ohio. His love for the game of football and all things Cleveland Browns turned Mike into a pro blogger years ago. Now Mike enjoys writing about all thirty-two NFL teams, hoping to help football gamblers gain a slight edge in their pursuit of the perfect wager.

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