Titans vs Bills Week 2: The Bills Are Lucky Enough to Have a Big-Armed QB Like Josh Allen
- The Titans lost to the Giants in Week 1 because their defense fell apart in the 2nd half
- Last week, the Buffalo Bills trounced all over the reigning champion LA Rams, 31-10
- Watch Titans vs Bills live on Monday, September 19, 2022, at 7:15 PM ET on ESPN
Titans vs Bills Odds
Odds taken from BetMGM. Click on the links below to head to the sportsbook and place your bet.
| Titans vs Bills Odds | Point Spread | Points Total | Money Line |
| Tennessee Titans | +10 (-105) BET HERE |
O49.5 (-115) BET HERE |
+350 BET HERE |
| Buffalo Bills | -10 (-115) BET HERE |
U49.5 (-105) BET HERE |
-450 BET HERE |
Titans vs Bills Pick
To cover a spread this wide there must be total domination and the way the Bills look on offense that is entirely possible, but Buffalo’s defense must also stop Titans RB Henry.
Bet on Bills to Cover the Spread
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The second game in the exciting NFL Week 2 Monday Night Football doubleheader is an AFC cross-divisional matchup that pits the 0-1 Tennessee Titans against the 1-0 Buffalo Bills, a chance for the Titans to earn their first win of the season and for the Bills to continue to roll.
HC Mike Vrabel’s Titans lost to the NY Giants in Week 1 because their defense fell apart in the second half and allowed New York to score a last-minute touchdown with a 2-point conversion that left Vrabel fuming, and now RB Derrick Henry’s rushing attack faces the Bill’s defense.
The first game of the NFL’s 2022 season was a TNF road blowout sponsored by the Buffalo Bills who trounced all over the reigning champion LA Rams, 31-10, the Bills defense with 7 sacks on the season already as QB Josh Allen continues to develop into a master craftsman.
Tennessee Titans vs Buffalo Bills Predictions
Can the Titans Defense Finish the Game in Week 2?
In Week 1 of the 2022 season, the Tennessee Titans defense looked dominant in the first half keeping the opposing New York Giants out of the end zone and off the scoreboard allowing the team to go into the locker room with a confident 13-0 lead that seemed well earned.
Then in the second half, the Giants made an adjustment, and the Titans defense paid the price allowing 21 points including a last minute touchdown and 2-point conversion that lost them the game, a failure by DC Shane Bowen’s crew that they have no doubt been attempting to fix.
The Buffalo Bills offense is top-7 right now and QB Josh Allen and Stefon Diggs are only just getting warmed up, so Tennessee’s defensive playmakers – DT Jeffrey Simmons, LB Bud Dupree, CB Caleb Farley, and FS Kevin Byard – had best bring their A-game to Orchard Park.
Can the Bills Stop Titans RB Derrick Henry from Dominating?
One of the factors that led to the Bills controlling the LA Rams in Week 1 was their ability to stop LA’s efficient run game as Buffalo’s defense kept the Rams RB crew to just 52 total yards on the ground, their longest run an 18-yarder with zero LA backs making it into the end zone all game.
The Bills’ strong rush defense will no doubt come in handy in Week 2 when Buffalo hosts the Tennessee Titans and their star RB Derrick Henry, a 6’ 3” 247 pound 2x NFL rushing yards leader who was out for much of last season due to a broken foot, though he is healthy now.
Henry averages 4.8 yards per carry and his speed and size and power make him tough to tackle, so watch for Bills LBs Matt Milano, Tremaine Edmunds, and rookie Christian Benford to match up with Henry and attempt to neutralize his efforts, a tough assignment for anyone.
Titans Key Player: (WR) Treylon Burks
The Tennessee Titans front office decided this offseason to add a sizable receiver to the roster who will give QB Ryan Tannehill another dependable target, so they used their first-round draft pick (18th selection overall) to snag Arkansas star Treylon Burks who fits the desired mold.
That move is already paying off with Burks on the field in Week 1 catching 3 of the 5 passes he was targeted with for 55 total yards, his longest a 27-yarder, a solid opening performance for a player brand new to the league now facing professional cornerbacks and safeties on the field.
A former First-team All-SEC player who caught 146 passes for 2,399 yards and 18 TDs when he was a Razorback, Burks can also run with the ball having posted 38 carries for 222 yards and a touchdown while playing at Arkansas, a Deebo Samuel type range that could be useful.
Bills Key Player: (WRs) Stefon Diggs and Gabe Davis
The Buffalo Bills are lucky enough to have a big-armed QB like Josh Allen, and his threat increases exponentially with the solid WR room he can target including deep threat playmaker Stefon Diggs and 3rd year player Gabe Davis, a duo that likes to abuse opposing defenses.
Last week those three offensive players were crucial to the Bills’ first win, with QB Allen (26/31, 297 yds, 3TD, 2 INT) struggling to take good care of the ball while counting on veteran receiver Stefon Diggs (8 rec, 122 yds, TD) to bail him out, a partnership that will continue to develop.
The solid #2 receiver ready to have a breakout season is Gabriel Davis whose Week 1 numbers (4 rec, 88yds, TD) are a sign of good things to come, last year posting 35 catches off 63 targets for 549 yards and 6 TDs, his size – 6’ 2” and 210 pounds – making him difficult to take down.
BetMGM: $1,000 Risk-Free Bet
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21+ New Customers Only. Subject to eligibility requirements. Bonus bets are non-withdrawable. Offer not available in DC, MS, NY, NV, ON, or PR. Gambling problem? Call 1-800-GAMBLER
How to Watch Titans vs Bills
| What | Tennessee Titans vs Buffalo Bills |
| Where | Highmark Stadium in Orchard Park, New York |
| When | Monday, September 19, 2022; 7:15 PM ET |
| How to watch | ESPN |
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