Best College Football Bets Week 10 | CFB Picks & Predictions

There are a couple of massive matchups in the SEC and throughout the country in Week 10. The season is coming down to the wire, and every game is magnified at this point in the year. Check back every Friday for our best college football bets of the week.

UConn @ #19 Tennessee

• Date: Saturday, November 4

• Time: 12:00 pm EST

• Moneyline: UConn (+160) | Tennessee (-194)

• Spread: UConn +34.5 (-114) | Tennessee -35.5 (-106)

• Total: Over 54.5 (-110) | Under 54.5 (-110)

Odds via DraftKings Sportsbook. Bet $5, Get $200 in Bonus Bets using our exclusive link.   

PICK: Tennessee 1st Quarter -7.5

The best value is in the games that nobody cares about, and we have that this weekend when Connecticut travels to Tennessee. UConn was expected to be bowl-eligible, but they can barely win a game, and they’ll have a tough time competing on Saturday as a 35.5-point underdog to Tennessee.

The atmosphere, the competition, and the speed of play is nothing like UConn has seen this season. They were outgained 433 to 222 by Boston College last week, and Tennessee is ten times more explosive than the Eagles.

As much as we like Tennessee to dominate, the best spread in this game is the first quarter line at -7.5. Tennessee has the fourth-best defense in the country, allowing just 327.5 yards per game. UConn cannot throw with Ta’Quon Roberson, and they won’t be able to compete up front with Tennessee.

I see the Volunteers scoring quickly. UConn allows 167 yards per game on the ground and 237 through the air against a moderate independent schedule. They also have covered -7.5 in the first quarter of their past two games against Kentucky and Alabama, so they have been starting fast. If Joe Milton is on his game, there is no reason we won’t see it be 14-0 after the first quarter.

#13 LSU @ #8 Alabama

• Date: Saturday, November 4

• Time: 7:00 pm EST

• Moneyline: LSU (+138) | Alabama (-166)

• Spread: LSU +3 (-105) | Alabama -3 (-115)

• Total: Over 60.5 (-110) | Under 60.5 (-110)

Odds via FanDuel Sportsbook. Bet $5 on Moneyline at FanDuel, and get $150 in Bonus Bets.  

PICK: Alabama -3

There is a lot of money and bets on LSU in this game, which isn’t surprising. The Tigers' offense continues to dominate, and their defense has given the perception they can play.

The Tigers' past two games were a 62-0 win against Army and a 48-18 victory versus Auburn. We’re not sold on the defense following two dominant games because, in the two games before this, they allowed a combined 88 points to Ole Miss and Mizzou.

We know Jayden Daniels will be fine in this game, but can they keep pace against an Alabama team that should be able to score at home? Alabama has the third-best defense in the SEC, allowing just 306 yards per game.

LSU allows 395 yards per game and 26.5 points. Alabama gives up ten fewer points per game than the Tigers. Defensively, LSU hasn’t figured it out despite their two good performances. On the other hand, the questions for Alabama circulate Jalen Milroe.

Is Milroe ready for this moment? He wasn’t against Texas earlier in the season. The matchup isn’t difficult against LSU's defense, but there is pressure to score because they can’t leave the door open for Daniels to put up points.

Milroe hasn’t been spectacular, but he has seven touchdowns to two interceptions in his past three games. Also, running back Jase McClellan has come alive, pounding the rock, and we believe he will have another big night following his 115-yard game against Tennessee.

With how Georgia has looked this season, the SEC East winner has a legitimate chance to make the College Football Playoff. LSU needs Ole Miss to lose to Georgia if they win out, which is likely, and Alabama controls its destiny, so this is an unofficial SEC East title game.

The revenge factor played into this for Alabama last season, and we believe this team has rallied around Milroe. This will make the difference in what should be a tight game.