Best College Football Bets Week 7 | CFB Picks & Predictions

The Week 7 college football slate isn’t like the ones we have seen in the past few weeks. However, a few teams are on upset alert, and the slate still has betting value. The headlining game is Notre Dame vs. USC, which should be highly contested. 

The Irish need to bounce back following a bad loss to Louisville in Week 6. We’ll break this game down and more in our best bets article. 

We break down our favorite plays every week on WSN. Make sure to check back every Friday for the best college football bets on the slate!

#10 USC @ #21 Notre Dame 

• Date: Saturday, October 14
• Time: 7:30 pm EST
• Moneyline: USC (+118) | Notre Dame (-142)
• Spread: USC +2.5 (-105) | Notre Dame -2.5 (-115)
• Total: Over 60.5 (-110) | Under 60.5 (-110)

Odds via FanDuel Sportsbook. Bet $5, Get $200 in Bonus Bets using our exclusive link. 

PICK: USC ML (+118)

The Notre Dame Fighting Irish haven’t been good as of late. They have dropped two of their past three games, losing to Louisville and Ohio State. They survived against Duke 21-14, but this game was much closer than the score showed. 

The Blue Devils were able to win at the end of the game, but late mistakes gave the contest back to the Fighting Irish. They also should have covered the spread, but a lack of tackling in the final minute blew the cover for Duke bettors. 

USC is 6-0 and the 10th-ranked team in the land, but they’re still an underdog against Notre Dame. This isn’t an excellent spot for the Trojans being on the road against a strong Notre Dame team. The Irish have underperformed the past few weeks but are still a talented team. 

This is one of the most exciting matchups to handicap on the college football slate. Notre Dame needs to play better, but they have a defense allowing under 279 yards per game. 

USC is a great offensive team that will find ways to score points, but they also need better qualities on defense. They allow 421 yards of total offense per game and haven’t gotten into the best opponents on their schedule. 

The Trojans' defense is why they survived Arizona in a triple-overtime thriller last week. Even though USC isn’t good on defense, and they’re being given points, we still believe they’re the better team. 

Sam Hartman looked atrocious last week, and this offense had no fight. USC will allow points, and Notre Dame can score 40 in this contest, but the Trojans offense will find a way to put a few more points on the board. 

Williams has thrown for 1822 yards this season with 22 touchdowns to just one interception. The Trojans' offense will find a way to win on the road to start the gauntlet of their 2023 schedule. 

Auburn @ #22 LSU

• Date: Saturday, October 7
• Time: 7:00 pm EST
• Moneyline: Auburn (+340) | LSU (-144)
• Spread: Auburn +11.5 (-115) | LSU -11.5 (-105)
• Total: Over 60.5 (-110) | Under 60.5 (-110)

Place just a $5 bet on FanDuel, and get $200 in Bonus Bets. 

PICK: Auburn +11.5

The Auburn Tigers have a very tough challenge this week in Death Valley. They’re playing on a Saturday night at Tiger Stadium, one of the country's most demanding environments. The one saving grace they have coming into this matchup is that LSU doesn’t play an ounce of defense, and we will take advantage of this for betting. 

Sportsbooks are giving 11.5 points for Auburn, which is a significant line against a team that doesn’t play defense. LSU allows 445.7 yards of offense per game, which includes 160 yards on the ground. 

Their defensive issues were on full display for LSU against Missouri. Mizzou had 527 yards of offense, including 23 first down and 39 points. LSU’s defense played better than in weeks past, but it wasn’t enough to slow down the Tigers. 

LSU did force two turnovers, and Jayden Daniels was fantastic on offense, which won them the game. However, the Tigers were a few plays away from their third loss of the season. 

Auburn isn’t getting a lot of respect in the SEC, but 11.5 points is too much, even on the road. The Tigers lost to Georgia by seven points at home, and the Bulldogs are much better than LSU. They were blown out at Texas A&M, but the Aggies are much better on defense than LSU. 

Auburn must score a lot in this game, but they won’t face much resistance against LSU. Look for them to keep this game close, even in Death Valley.