Best Broncos vs. Eagles Prop Bets: Can Bo Nix Stand Up Against the Eagles' Talented Secondary?

• JK Dobbins is averaging 5.7 YPC in 2025

• RT Lane Johnson is questionable to play on Sunday

• All four of the Eagles' games this season have been decided by 7 or fewer points

Week 5 of the NFL season brings us a fantastic slate of games, but a potential Super Bowl matchup may be the best. The Denver Broncos will head East to take on the Philadelphia Eagles, who may be without several key players. That has us confident that this will be a close game, even if it isn’t always pretty. 

Below, we will share our three bets for this NFC matchup. All odds are courtesy of Caesars Sportsbook. If you’d like to give Caesars a try, use our promo code WSN20X to claim a “Bet $1, Double Your Winnings on Next 20 Bets” offer.

Caesars is ranked as one of our top recommended NFL betting sites. For more promos, check our best NFL betting promos.

JK Dobbins Anytime TD (+140) at Caesars Sportsbook

While his name isn’t being tossed around for NFL MVP, JK Dobbins has been incredible for the Broncos in 2025. He’s averaging 5.7 YPC, registering 323 yards and three touchdowns through four games. While he is splitting carries with rookie RJ Harvey, who has also played well, Dobbins remains the top back. Last week, the veteran rushed for 101 yards in just 16 carries.

There is a lot to like about the Eagles' defense, but its ability to stop the run isn’t one of them. The team is allowing opposing teams to average 4.8 YPC on the ground, which is the seventh-highest mark in the league. 

Philly’s strength is their pass defense, with a trio of corners that have dominated opposing receivers through the first three weeks. Given that Bo Nix can be prone to turnovers, we expect Dobbins to see a lot of carries, which will allow him to find the end zone at least once this weekend.

Use code WSN20X and Double Your Winnings at Caesars

Under 22.5 First Half Points (-129) at Caesars Sportsbook

The Broncos have one of the best defenses in the NFL, and they may have a significant advantage heading into Sunday. That’s because the Eagles have been hammered by injuries, including veteran RT Lane Johnson. If he is out or hobbled by the injury, it will allow Denver’s fearsome defensive front to pressure and hurt Barkley behind the line of scrimmage.

We really don’t like Bo Nix’s chances of succeeding in Philly on Sunday. It’s one of the toughest places to play in the NFL, and the Eagles' secondary will force him to make mistakes. We like Nix and his talent, but he has also shown that he can let emotions get the best of him. Sean Payton will want to protect his young quarterback in this one, leading to a heavy dose of the run game. 

Bet $1 at Caesars and Get 20 100% Profit Boost Tokens

Yes Overtime (+929) at Caesars Sportsbook

Bookmakers are being conservative with their prop bets for this game, thanks to the unknown status of several key Eagles. That has us looking at some longshot bets, and this one stands out.

We believe this will end up being a low-scoring slugfest, which will significantly increase the likelihood of overtime. Look for both offenses to be frustrated, resulting in long, run-heavy drives all day. Given that Caesars has the Eagles at -3.5 and a total set at 43.5, it seems they agree.

It’s also worth pointing out that these teams have been playing close games. Seven or fewer points have decided all of the Eagles' games. The Broncos have seen three of their four games decided by no more than one score. The only exception came last week, when the Broncos beat up on a Joe Burrow-less Bengals team at home.

Get 20 100% Profit Boost Tokens at Caesars With a $1 Bet

More NFL Week 5 Stories

• NFL Odds Week 5

• NFL Picks Against the Spread Week 5

• Anytime Touchdown Scorer Predictions in Week 5

• Bills vs Patriots Same Game Parlay SNF Week 5