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Colts vs Broncos Week 5: Expect a Low-Scoring Defensive Battle

Written by: Mike Lukas
Updated October 14, 2022
17 min read
  • The Indy Colts are monitoring RB Jonathan Taylor (ankle) who is questionable to play
  • Denver Broncos RB Javonte Williams is feared to have suffered a serious knee injury
  • Watch Colts vs Broncos on Thursday, October 6, 2022, at 8:15 PM ET on Prime Video

Colts vs Broncos Week 5 Odds

Odds taken from Caesars Sportsbook. Click on the links below to head to the sportsbook and place your bet.

Colts vs Broncos Odds Point Spread Points Total Money Line
Indianapolis Colts +3.0 (-100)


O43 (-110)




Denver Broncos -3.0 (-120)


U43 (-110)




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Colts Vs Broncos Predictions Russel Wilson

Colts vs Broncos Week 5 Picks

Point Spread: Denver Broncos -3 (-120) at DraftKings

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The 1-2-1 Indianapolis Colts have been starting games out slow this season and it has gotten them in the kind of trouble that’s been tough to climb out of so expect the Denver Broncos to cover this narrow spread at home as their new QB Russell Wilson continues to look like his old self so far with four passing TDs to just one INT.

The biggest news now for the Colts is the ankle injury to RB Jonathan Taylor which leaves him questionable for this one putting stress on an already struggling rushing attack ranked 27th in the league, most likely a refreshing opponent for Denver’s 18th-ranked run defense that can help keep Taylor’s replacements – most likely Nyheim Hines and Deon Jackson – in better check.

As Colts new veteran QB Matt Ryan continues to absorb Indy OC Marcus Brady’s offensive game plan (one that takes full advantage of deep threat WR Michael Pittman Jr.) watch for that part of their game plan to improve, though Denver might use CB Pat Surtain II to attempt to neutralize him, a battle worth watching that should keep this exciting matchup close.

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Point Total Under 43 (-110) at BetMGM

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For this bet it pays to do a little research and look up how much these two teams typically score, and so far during the 2022 season, the Indy Colts score an average of 14.3 points per game and the Denver Broncos put up an average of 16.5 points per game so that total – 30.8 points – is far less than what the oddsmakers are predicting.

Of course, some things could change those totals, like the fact that this game is in Denver so there is a home team advantage plus there is a thin altitude to consider that could affect how many field goals are made, but that could also affect the players and cause them to become short of breath quicker than normal which could keep the scoring there lower than normal.

It is also good to consider the fact that the Denver Broncos have a top-4 defense so they will be tough to score against, so take the under here and expect a low-scoring defensive battle, these two teams with plenty of playmakers on that side of the ball including the Colts’ DE Kwity Paye and DT DeForest Buckner and the Broncos’ DE Dre’Mont Jones and LB Bradley Chubb.

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Money Line Denver Broncos (-170) at FanDuel

With no point spread to consider, take the Denver Broncos to win here straight out since they are at home and QB Russell Wilson is a talented team leader although his 21st-ranked offense could struggle against these Colts whose 6th-ranked defense keeps opponents to under 300 total yards per game so far this season.

The Broncos offense is packed with playmakers who should be able to thrive including deep threat WRs Courtland Sutton and K.J. Hamler who help their slot man Jerry Jeudy by stretching out the field, also a bonus for Denver’s run game featuring Melvin Gordon and Mike Boone, a duo that is part of an 18th ranked rushing attack that could become effective in colder weather.

Be sure to keep an eye out on the Indianapolis side of the ball for rookie WR Alec Pierce who has already seen some action with 7 catches off 13 targets for 141 yards averaging over 20 yards per reception, his longest a 44-yarder that will force the Denver secondary to give the young speedster respect, his 4.41 second 40-yard dash time enough to turn some heads.

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How to Watch Colts vs Broncos

  • What: Indianapolis Colts vs Denver Broncos
  • Where: Empower Field at Mile High in Denver, CO
  • When: Thursday, October 6, 2022; 8:15 PM ET
  • How: Prime Video
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Mike Lukas

1204 Articles

Mike Lukas is a retired standup comedian turned freelance writer now living in Dallas, Texas, originally from Cleveland, Ohio. His love for the game of football and all things Cleveland Browns turned Mike into a pro blogger years ago. Now Mike enjoys writing about all thirty-two NFL teams, hoping to help football gamblers gain a slight edge in their pursuit of the perfect wager. Email: [email protected]

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