Eagles vs Colts Week 11: The Underdogs Have Won Nine of the Colts’ Last 13 Games

• The Philly Eagles just got their first loss of 2022 to the Washington Commanders, 21-32
• Indy Colts’ interim HC Jeff Saturday is 1-0 with QB Matt Ryan back under center
• Watch Eagles vs Colts live on Sunday, November 20, 2022, at 1:00 PM ET on CBS

Eagles vs Colts Week 11 Odds

The odds in the table below are provided by BetMGM, FanDuel and DraftKings. Click on “Bet Here” to head to the sportsbooks and place your bet.

Eagles vs Colts Week 11 Picks

• POINT SPREAD: Indianapolis Colts +6.5 (-110) at BetMGM
• POINTS TOTAL: Over 44.5 (-114) at FanDuel
• MONEY LINE: Philadelphia Eagles (-295) at DraftKings   

Point Spread: Indianapolis Colts +6.5 (-110) at BetMGM

 Get ready for the NFL’s fantastic Week 11 lineup including this thrilling cross-conference matchup between the 8-1 Philadelphia Eagles and the 4-5-1 Indianapolis Colts, with the Eagles finally falling so that now their one-loss HC Nick Sirianni must face the Colts undefeated interim HC Jeff Saturday, two talented teams looking at the postseason from very different angles.

Given that Philadelphia has failed to cover the spread in five of their last six road games and that Indianapolis has a tremendous amount of forward momentum going their way right now thanks to their much-questioned new coach Saturday helping them post a Week 10 win over the spiraling LV Raiders, 25-20, proof that veteran QB Matt Ryan should be starting under center.

What beat the Eagles in Week 10 was their carelessness with the football, with QB Jalen Hurts throwing an interception and the team losing three fumbles in that first loss of the season, something that the Colts defense can game plan around, that unit responsible for four interceptions and six forced fumbles this season, low numbers if Indy plans on winning outright.

Points Total: Under 44.5 (-114) at FanDuel

There has been a tendency during the 2022 NFL season for low scores in quite a few games, the reason being partially due to how long it took to knock off the teams’ offseason rust thanks to a shorter preseason, so it makes sense that 13 of the Colts' last 15 games have gone under the total points line, especially given how much drama the team has endured.

Colts owner Jim Irsay fired HC Frank Reich for all the team’s losses right after forcing Reich to start the young backup QB Sam Ehlinger instead of veteran hurler Matt Ryan, and then the subsequent hiring of interim HC Jeff Saturday, a former Pro Bowl center with no head coaching experience and essentially Irsay’s former consultant, has brought unflattering attention their way.

But a big Week 10 win over the Raiders shut up the doubters, but now the Eagles have had HC Saturday’s game film to watch and prepare for, so expect these two teams who typically score under what this bet allows to do the same in this one and given that Lucas Oil Stadium has a retractable roof, the brisk Indiana November weather should not be a major factor in this game.

Money Line: Philadelphia Eagles (-295) at DraftKings

The good news for Indianapolis Colts fans is that the underdogs have won nine of the Colts' last 13 games, so those of you who believe that trend will continue in Week 11 should make this money line bet for $100 on Indy and if they manage to hand the Eagles their second loss, winners would get a $245 payout plus your initial investment, a decent reward for believing in the dog here.

For those who believe the Eagles will shake off that loss and take care of the football enough to get their winning ways back on track, a $295 money line bet on the Eagles would pay winners $100 plus the original wager, a risky venture that seems less dangerous when you consider how much better the Eagles are (4th ranked offense, 3rd ranked defense) than the Colts (24th ranked offense, 4th ranked defense), though that’s on paper and this game takes place on the gridiron.

Make sure to check back at game time for any important injuries that could keep playmakers off the field including two Philadelphia Eagles who will be the coach’s decisions – TE Dallas Goedert (shoulder) and CB Josh Jobe (hamstring) – and three Indy Colts listed as questionable to play including RB Deon Jackson (knee), DE Kwity Paye (ankle), and TE Jelani Woods (shoulder).

How to Watch Eagles vs Colts

• What: Philadelphia Eagles vs Indianapolis Colts
• Where: Lucas Oil Stadium in Indianapolis, IN
• When: Sunday, November 20, 2022, at 1:00 PM ET
• How: CBS