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Image for Richard Janvrin Richard Janvrin - Updated October 14, 2022

Monday Night Football Predictions & Best Bets

Nfl Mnf Best Bets

Click here for our MNF Week 3 best bets for Giants vs Cowboys.

For Week 2, Monday Night Football will feature two matchups.

The first of the night is the Tennessee Titans on the road against the Buffalo Bills, followed by the Minnesota Vikings traveling to face the Philadelphia Eagles.

Here, we have the three best bets for these two games.

Monday Night Football Best Bets

Buffalo Bills -10 (-110) at DraftKings



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Taking on the Titans at home, the Bills showed us in Week 1 that they can absolutely shut teams down.

In the past, the Bills defense was always excellent but was built in a way that allowed the opposing team to run on them.

Against the Titans, this would be an issue with running back Derrick Henry as the main cog in this offensive wheel.

However, the Bills have tried to bolster this part of their defense, with guys like Tim Settle, DaQuan Jones, and Jordan Phillips working together to plug up the middle.

The Titans were almost destitute on offense against the New York Giants as quarterback Ryan Tannehill has no one to throw to, really.

His top receiver was Kyle Philips, a fifth-round rookie out of UCLA.

There’s not a single aspect of this game in which the Titans look to be better. Expect the Bills, at home, to shut them down.

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Buffalo Bills vs. Tennessee Titans Under 47.5 (-110) at BetMGM



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With the guys up the middle working to contain Henry and the coverage having the ability to to approach one-on-one matchups against any Titans pass catcher, this is going to limit what the Titans can do on offense.

With Tannehill at quarterback and Henry at running back, they’ll still score points, but dropping 20 as they did in Week 1 seems unlikely.

Remember, the Bills held the Super Bowl champion Los Angeles Rams to just 10.

Unless the Titans can get Henry going early and rely on him to run the offense, the Titans may be closer to that 10-point mark than 20, leaving the Bills with many points to make up for.

This total is too high.

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Philadelphia Eagles vs. Minnesota Vikings Over 49 (-110) at Caesars



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In Week 1, both the Eagles and Vikings were fantastic.

The Eagles scored 35 points, and the Vikings looked dominant on offense with wide receiver Justin Jefferson as their unrecoverable asset.

With this total set at 49, both teams should be able to score many points and get that over.

The Eagles scored 35, yes, but they allowed 32 to the Detroit Lions.

We saw how the Vikings mixed up how they use Justin Jefferson, and he’s a bit of a cheat code. The Eagles may deploy Darius Slay to shadow him. Still, he was the only cornerback on the Eagles to allow a touchdown last week.

For the Eagles offense, they have A.J. Brown, who was terrific but also have DeVonta Smith, who may have been a non-factor in Week 1. Still, he’ll cause the Vikings secondary issues as safety Harrison Smith can’t be in two places at once.

Hurts can also move the chains with his legs, picking up 90 yards in Week 1 and mixing in their running back depth chart.

Speaking of running backs, the Vikings have Dalvin Cook, who had 90 rushing yards on 20 carries last week, and gets an Eagles defensive front that only saw Haason Reddick perform well in run defense, and he plays on the outside.

This will be a high-flying, fast-paced affair as both teams should finish anywhere from the mid-20s to the 30s.

Head over to Caesars Sportsbook using our link to create an account and nab a $1,250 risk-free bet.

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Richard Janvrin

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After graduating from the University of New Hampshire with a BA in Journalism, Richard Janvrin has been covering iGaming and sports betting since December 2018. Richard has covered betting at Bleacher Report, Gambling.com, The Game Day, Forbes, and more.

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