When you sign-up through links on our site, we may earn an affiliate commission. Learn more >

NFL Week 16 Parlay: Best NFL Parlays for Week 16

Written by: Michael Sicoli
Published December 22, 2023
8 min read

Last week’s parlay came a Drew Lock drive away from hitting. Hopefully, Week 16 will provide less pain. Here is your weekly dosage of parlays!

The Parlay

Lines from DraftKings Sportsbook. Wager $5 and get $150 in bonus bets at DraftKings! 

PickOddsPayout (Increasing with each leg, top to bottom)
BUF @ LAC: ALT Bills -9.5-153
$10 to win $16.53
SEA @ TEN: Seahawks -2.5-115
$10 to win $30.91
ARI @ CHI: ALT OVER 40.5-158
$10 to win $50.48
DAL @ MIA: Jake Ferguson anytime TD+140
$10 to win $121.15
CIN @ PIT: Tanner Hudson o28.5 receiving yards-120
$10 to win $222.11
Best NFL Parlays Week 16

Leg #1 - BUF @ LAC: ALT Bills -9.5 (-153) at DraftKings

The Bills have rounded into form with wins over the Chiefs and Cowboys over the last two weeks. Meanwhile, Aidan O’Connell and the Raiders just obliterated the Chargers on national television a week ago.

This Chargers team is among the worst of the worst without Justin Herbert under center. The franchise quarterback isn’t coming back anytime soon, creating good value for a Buffalo team in desperate need of wins.

One of these teams is red-hot, and the other is not. Take the Bills with some confidence, especially if you buy points to bring it to -9.5.

Take note that teams can rally after a coach is fired. Brandon Staley’s firing could cause some pause. Trust the talent to work this one out.

Place your bets at DraftKings and get $150 in Bonus Bets.

Leg #2 - SEA @ TEN: Seahawks -2.5 (-115) at DraftKings

This doesn’t make sense. The Seahawks should return Geno Smith this week, and with their shocking win over Philadelphia in Week 15, Seattle cannot drop this game.

Meanwhile, the Titans just choked a lead and subsequently the game to a Case Keenum-led Texans team that also was without Nico Collins, Tank Dell and Will Anderson, to name a few. These teams are in different brackets in terms of current motivators.

Similarly to Buffalo, ride the hot hand against a team that is close to ice cold.

Use our exclusive link and place your bets at DraftKings Sportsbook.

Leg #3 -  ARI @ CHI: ALT OVER 40.5 (-158) at DraftKings

This over has hit in seven of Justin Fields’ nine games, excluding Week 6 when he left the game early. Both of these teams still allow plenty of points.

With each team returning starting quarterbacks in Fields and Kyler Murray in recent weeks, there is no reason to expect the offenses not to put up points. The Cardinals have put up 24 and 29 points against the Steelers and 49ers, respectively, and should keep that trend going against the Bears.

This over has also hit in three of Kyler Murray’s five starts.

Wager $5 at DraftKings and get $150 in Bonus Bets!

Leg #4 -  DAL @ MIA: Jake Ferguson anytime TD (+140) at DraftKings

Here’s a bit of a stab in the dark. The Dolphins have allowed just three touchdowns to tight ends this season, but that doesn’t tell the full story.

Miami still allows 75% of opposing targets to tight ends to be completed, albeit for only a 14th-ranked 688 yards. Completed passes are realistically all that are needed when it comes to touchdowns, and Ferguson’s usage is a bit different than the average tight end.

Only teammate CeeDee Lamb has seen more red zone targets than Ferguson, whose 22 targets have yielded five touchdowns this year. That leads all tight ends, with the Wisconsin product seeing five more red zone targets than the great Travis Kelce. The Cowboys utilize tight ends more than the average team, adding some value at +140. 

Head over to DraftKings to place your bets on NFL games!

Leg #5 -  CIN @ PIT: Tanner Hudson o28.5 receiving yards (-120) at DraftKings

The Steelers have been decimated by injuries in recent weeks. With countless holes at linebacker and safety — Damontae Kazee has been suspended while Minkah Fitzpatrick is out with a knee injury — expect Jake Browning to lean on his tight end.

Hudson has routinely put up good numbers over the last month, hitting this over in five of his last seven games. With Ja’Marr Chase also out with a shoulder injury, there should be even more of a focus to find Hudson across the middle.

The Steelers allow 47.4 receiving yards per game to tight ends.

Head over to DraftKings Sportsbook to place your parlay bets using our exclusive link!

Bet $5, Get $150 in Bonus Bets

21+ | Terms and conditions apply

Claim Now
Image for Michael Sicoli


Michael Sicoli

58 Articles

Michael Sicoli has been writing about fantasy football and betting within the NFL space since 2020. He works as a writer and content creator with ClubFantasyFFL and runs an NFL defensive (IDP) newsletter with The IDP Guys. A graduate from Quinnipiac University, Michael is a long-time NFL fan with a love for soccer and the NBA.

More info on Michael Sicoli
We've been featured on:
espn logo
reuters logo
cbs-news logo
forbes logo
entrepreneur logo
entrepreneur logo
We only list licensed sportsbooks

© Rebel Penguin ApS 2024 (a subsidiary of Gaming Innovation Group Inc.)

We support responsible gambling. 21+ Only. Gambling problem? Call 1-800-Gambler.

WSN.com is run by iGaming Cloud Inc (a Gaming Innovation Group Subsidiary) and is registered with the New Jersey Division of Gaming Enforcement (DGE) under affiliate vendor ID 89744, with the Indiana Gaming Commission (IGC) under certificate of registration number SWR-000148, approved by the Pennsylvania Gaming Control Board as a gaming service provider, under certificate registration number 117656-1, possesses a Vendor Minor sports betting license from the Colorado Limited Gaming Control Commission (account number 94414163), granted a vendor registration number VR007603-20-001 by the Michigan Gaming Control Board, an interim Sports Wagering Supplier license, under license number SWS 066, issued by the West Virginia Lottery Commission, a sports betting vendor registration, under registration number #100400, issued by the Director of Gaming Licensing and Investigations of the Virginia Lottery to operate in the State of Virginia, and a Vendor Registration issued by the Sports Wagering Committee of the Tennessee Education Lottery Corporation.

Advertising disclosure: WSN contains links to online retailers on its website. When people click on our affiliate links and make purchases, WSN earns a commission from our partners, including ESPN and various sportsbooks.