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Chicago White Sox vs Cleveland Indians Predictions, Betting Odds & Picks

Written by: Tony Garcia
Updated October 14, 2022
5 min read
White Sox Vs Indians
  • Pitching matchup might be closer than one might think
  • Can Cleveland offense keep pace with Chicago?
  • X-factor to watch on both sides

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Chicago White Sox vs Cleveland Indians Odds

Team Run Spread Money Line Total
Chicago White Sox +1.5 (-175)
O 7 (-122)
Cleveland Indians -1.5 (+143)
U 7 (EVEN)

Odds from PointsBet. Get up to four RISK FREE bets up to $1000 or check out more offers and promo codes for the best online sportsbooks.

  • White Sox are 5-1 in the last six games
  • Under is 5-1 in White Sox last six road games
  • Under is 10-3 in White Sox last 13 road games
  • Indians are 11-5 in the last 16 head-to-head meetings
  • Indians are 10-4 in the last 14 games vs AL Central teams
  • Over is 6-2 in Indians last eight home games
  • Indians are 14-6 in their last 20 games as a home favorite.

Chicago White Sox vs Cleveland Indians Predictions and Picks

Our Pick
It hasn’t been quite as easy as just picking the Indians when Shane Bieber is pitching like it was in 2020 The Indians were 10-2 in those 12 occasions last year and they’re 8-3 in 11 starts this year. The White Sox meanwhile have won seven of nine and are playing well of late.
The best odds for this match Odds provided by PointsBet
Chicago White Sox Moneyline (+125) Bet Now

Garcia’s 2021 record: (21-16-2)

How to watch Chicago White Sox vs Cleveland Indians

 Chicago White Sox vs Cleveland Indians Information
Teams Chicago White Sox vs Cleveland Indians
Location Progressive Field, Cleveland, Indiana
Time Tuesday, June 1, 6:10  p.m. EST
How to Watch FS1

The Pitching Matchup Should Be a Good One

THere’s absolutely no doubt about the fact that Shane Bieber is one of the best pitchers in baseball. But as of the last month, he hasn’t been as sharp as his Cy Young season in 2020, even though he has an extremely high strikeout rate.

Bieber is 5-3 with a 3.13 ERA and 1.21 WHIP — great numbers, but nothing that suggests he’s one of the most dominant arms in the game. That said, he does pace the league with 110 strikeouts in 72 innings. He comes off one of his best games of the season, when he went seven innings and gave up just one run on one hit while striking out 12 in a 5-2 win over Detroit.

On the other side, White Sox starter Dylan Cease is having the best start to a season of his young career, which could make this one could be a sneaky tight pitching matchup.

Cease is 3-1 with a 2.98 ERA and 1.27 WHIP and has been great the past month. In his last six starts, he’s given up one run or fewer in four of those starts and struck out nine or more batters three times. While Bieber has the experience, Cease is going against a lineup that’s not as deep so this should be a very tight ball game.

Can Cleveland Keep Pace With Chicago Offensively?

Runs are going to be at a premium in this game and sometimes it just comes down to which side can get it done. Overall, the clear advantage in this one goes to Chicago, because while they lead Cleveland by just 3.5 games in the standings, they’ve outscored them by nearly 50 runs on the season.

Perhaps no stat illustrates this point better than an on-base percentage. The White Sox have five everyday players who have an OBP above. 350. Cleveland doesn’t have a single one.

Yoan Moncada has led the way this year for Chicago — further illustrating the point of the team’s depth after just last season the south-siders had two other players finish in the top 10 in MVP voting, one of course who won the award in Jose Abreu. Moncada has a .421 OBP and a team-best 2.4 WAR (wins above replacement) almost a full win more than Tim Anderson (1.5) who is next.

X-Factor to Watch on Both Sides

We wanted to single out Jose Abreu as somebody to watch for because he’s been absolutely dominant the last week — he’s batting .375 with a 1.191 OPS with two home runs and 10 RBIs the last seven days  — but that’s a little too obvious since he is the reigning MVP.

So we will look at Nick Madrigal who hasn’t had the same power stroke but has been very effective. He’s batting .440 with a 1.100 OPS with a team-high 11 hits.

For Cleveland, it’s Cesar Hernandez who needs to really get his bat going. The Indian’s leadoff man is 3-for-25 over the last week with just two walks and eight strikeouts. It underscores a disappointing season for the 31-year-old outfielder who is hitting just a .216 batting average with a .684 OPS.

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Tony Garcia

Sports Betting Analyst

Betting Picks
Tony writes about baseball for WSN.com after recently graduating with his Masters from the Medill School of Journalism at Northwestern University. Prior to that, Tony was a local sports reporter for MLive Media Group, based out of Jackson, Michigan where he covered everything from high school to professional sports. He graduated from Michigan State in 2015 with a degree in journalism. During his time there he covered the Michigan State football and men’s basketball teams from 2013-15 and hosted a sports radio show on WDBM 89FM.
Nationality: American
Education: M.A. in Journalism
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