When you sign-up through links on our site, we may earn an affiliate commission. Learn more >

Dodgers vs Padres: NL West Heavyweights Meet for First Time in 2023

Written by: Bryan Zarpentine
Published May 5, 2023
11 min read
  • Friday’s MLB schedule includes the first meeting of the season between the Dodgers and Padres, two of the preseason favorites in the National League.
  • The Dodgers have scored 36 runs in their last three games and averaged seven runs per game over their last 11 games.
  • Clayton Kershaw is 5-1 with a 1.89 ERA over his first six starts of 2023.

Dodgers vs Padres Odds

Odds Taken from DraftKings Sportsbook

TeamRun LineTotalMoneyline
Los Angeles Dodgers-1.5 (+140)
O 7.5 (-115)
San Diego Padres+1.5 (-165)
U 7.5 (-105)

Cardinals vs Brewers Pick

Check out the best betting bonuses and promo codes for MLB, here!

🔥 Claimed by 131 people this week!



Get a No Sweat First Bet up to $1,500

21+ | T&Cs apply

Dodgers vs Padres Predictions

Friday’s MLB schedule features the first meeting of the season between the Los Angeles Dodgers and the San Diego Padres. Both teams began the season among the favorites in the National League, and while neither team got off to a great start in April, they remain serious contenders. The Padres want to start making amends for going 4-15 against the Dodgers during the 2022 regular season while the Dodgers would like some redemption after losing to San Diego in the postseason last year. 

The Padres spent most of April struggling to stay above .500. But they’ve finally started to heat up a little. They swept a two-game set in Mexico City against the Giants last weekend and then two of three games against the Reds earlier this week. That’s given them four wins in their last five games, pushing them two games over .500 despite a negative run differential on the year.

Alas, the Dodgers head to San Diego this weekend riding a six-game winning streak, making them the hottest team in baseball. A week ago, Los Angeles was 13-13 and behind the Diamondbacks atop the NL West. However, the Dodgers have swept the Cardinals and Phillies in back-to-back series to climb into first place in the division.

With the Dodgers winning six in a row, they are listed as road favorites in Friday’s series opener. DraftKings gives Los Angeles a moneyline of -125 compared to San Diego’s moneyline of +105, making the Padres a slight home underdog. Friday’s game also has an over/under of 7.5 runs.

San Diego Padres Predictions

For most of April, the San Diego offense couldn’t get anything going. Outside of Xander Bogaerts, there was little consistency. Stars like Juan Soto and Manny Machado got off to dreadful starts while Fernando Tatis Jr. missed the first chunk of the season because of a suspension. However, that has changed over the past week with the Padres scoring at least six runs in four of their last five games. In those five games, Soto is batting .471 with an OPS of 1.522. Machado, Jake Cronenworth, and Nelson Cruz have also heated up over the past week, although Bogaerts has hit his first slump of the season, so the San Diego lineup still isn’t firing on all cylinders.

On the pitching front, Joe Musgrove will make his third start of 2023. Musgrove managed to pick up a win in his first start, but he got hit hard in Mexico City against the Giants last Saturday, allowing seven runs on six hits over 6.1 innings. Obviously, the Padres don’t want to overreact to one poor start in a hitter-friendly environment. But Musgrove also has a troubling history against some of the top hitters in the Los Angeles lineups. Mookie Betts, Freddie Freeman, and Max Muncy are all key figures for the Dodgers, and that trio is a combined 25 for 61 (.410) with 10 extra-base hits against Musgrove. 

Los Angeles Dodgers Predictions

The Padres aren’t the only team in this game that’ starting to click offensively. The Dodgers scored 36 runs during their three-game sweep of the Phillies earlier this week and have averaged seven runs per game over their last 11 games. Muncy continues to provide plenty of power with 12 homers on the season. James Outman, Jason Heyward, and Will Smith have also helped to provide depth behind Betts and Freeman, who are both hitting .400 and have combined for nine extra-base hits in the team’s last six games. They remain the key figures in the Los Angeles lineup, particularly Betts, who often serves as the catalyst.

If that red-hot lineup isn’t enough for the Dodgers, they also have Clayton Kershaw getting the start on Friday. The 35-year-old looks several years younger, going 5-1 with a 1.89 ERA and a 0.76 WHIP over his first six starts of the season. Kershaw has pitched at least six innings in all six starts and struck out nine batters in three of the six starts, so he’s performed like he’s still in his prime early in 2023. Between Kershaw’s dominance early in the season, the Dodgers heating up offensively, and Musgrove’s woes against several prominent LA hitters, it’s hard not to think that the Dodgers are poised to win Friday’s series opener.

Dodgers vs Padres - Over/Under Analysis

With Kershaw and Musgrove on the mound, it makes sense for there to be a low over/under of just 7.5 runs in this game. But that number might be too low, especially with the way the Dodgers have been swinging the bats lately. On a related note, the Dodgers are hitting the over more than 61% of the time this year, including a 10-3-1 O/U record in their road games this season. With the way their best hitters have performed against Musgrove in the past, Los Angeles could be considered a threat to reach over 7.5 runs without any help from the Padres. That being said, San Diego’s lineup is too hot heading into this game not to push a few runs across the board, helping this game hit the over.

Logo #1



Bet $5, Get $150 in Bonus Bets

21+ | Terms and conditions apply

Logo #2



$500 Bonus Bet

21+ | VA only | Gambling problem? Call 1-800-532-3500

How to Watch Los Angeles Dodgers vs San Diego Padres

  • What: Los Angeles Dodgers vs San Diego Padres
  • Where: Petco Park, San Diego, California
  • When: Friday, May 5, 9:40 PM EST
  • How to Watch: SportsNet LA, Bailey Sports San Diego, and MLB Network
Image for Bryan Zarpentine


Bryan Zarpentine

193 Articles

Bryan Zarpentine is a 2008 graduate of Syracuse University and has been working as a freelance writer and editor since 2010. During that time, he has contributed to countless sites while covering baseball, soccer, the NFL, college football, and college basketball.

More info on Bryan Zarpentine
We've been featured on:
espn logo
reuters logo
cbs-news logo
forbes logo
entrepreneur logo
entrepreneur logo
We only list licensed sportsbooks

© Rebel Penguin ApS 2024 (a subsidiary of Gaming Innovation Group Inc.)

We support responsible gambling. 21+ Only. Gambling problem? Call 1-800-Gambler.

WSN.com is run by iGaming Cloud Inc (a Gaming Innovation Group Subsidiary) and is registered with the New Jersey Division of Gaming Enforcement (DGE) under affiliate vendor ID 89744, with the Indiana Gaming Commission (IGC) under certificate of registration number SWR-000148, approved by the Pennsylvania Gaming Control Board as a gaming service provider, under certificate registration number 117656-1, possesses a Vendor Minor sports betting license from the Colorado Limited Gaming Control Commission (account number 94414163), granted a vendor registration number VR007603-20-001 by the Michigan Gaming Control Board, an interim Sports Wagering Supplier license, under license number SWS 066, issued by the West Virginia Lottery Commission, a sports betting vendor registration, under registration number #100400, issued by the Director of Gaming Licensing and Investigations of the Virginia Lottery to operate in the State of Virginia, and a Vendor Registration issued by the Sports Wagering Committee of the Tennessee Education Lottery Corporation.

Advertising disclosure: WSN contains links to online retailers on its website. When people click on our affiliate links and make purchases, WSN earns a commission from our partners, including ESPN and various sportsbooks.