When you sign-up through links on our site, we may earn an affiliate commission. Learn more >

Carolina Panthers vs Dallas Cowboys Week 4 Predictions, Odds & Picks

Written by: Mike Lukas
Updated October 14, 2022
5 min read
Panthers Vs Cowboys
  • The main Panthers’ story is injury-related, Christian McCaffrey and Jaycee Horn both out 
  • The 2-1 Dallas Cowboys look like the best squad in the NFC East (for now)

Panthers vs Cowboys Odds

Odds for Panthers vs Cowboys Week 4 game taken from DraftKings Sportsbook

Team Point Spread Odds
Carolina Panthers +4
Dallas Cowboys -4

Play Fantasy Football Here!

🔥 Claimed by 139 people this week!



Get a No Sweat First Bet up to $1,500 in Bonus Bets

21+ | T&Cs apply

Here is your chance to win $600! Take a look at our NFL Pick ’em Contest!

Panthers vs Cowboys Week 4 Predictions and Picks

The main story for the Carolina Panthers is injury-related, with RB Christian McCaffrey (hamstring) and rookie CB Jaycee Horn (foot) both out on Sunday, so it will be up to rejuvenated quarterback Sam Darnold to continue reinventing himself away from the NY spotlight as he and HC Matt Rhule take their 3-0 show west to California.

After their decisive Week 3 win over the confused Philadelphia Eagles, the Dallas Cowboys look like the best squad in the NFC East (for now), mostly thanks to their healthy quarterback Dak Prescott and revitalized running back Ezekiel Elliott leading a team whose defense under new defensive coordinator Dan Quinn seems well-equipped to take on almost anything.

These two NFC rivals have met each other 14 previous times (including 2 postseason games), with the Dallas Cowboys winning 9 of those games and the Carolina Panthers winning 5 of the games.

Can the Banged-Up Panthers Produce Against this Revamped Dallas D?

Two huge injury-related losses for the Carolina Panthers with dual-threat running back Christian McCaffrey pulling up lame with a non-contact hamstring strain in Week 3 plus an injured foot to rookie starting cornerback Jaycee Horn will challenge this ever-evolving Panthers’ offense.

Quarterback Sam Darnold is in the midst of a personal revolution after having his NFL confidence torn to shreds in New York with the Jets, now with his Carolina head coach taking over the burden of leadership as the former USC superstar simply shows up on the field and plays.

It’s worked out so far, with no losses in 2021 as yet, while Darnold completes over 68 percent of his passes (compared with last season’s 59.6), and now Sam’s offense is down McCaffrey, so backups like running backs Chuba Hubbard and Royce Freeman (below) must step up.

Can the Cowboys Two-Headed Rushing Attack Continue to Be Effective?

This was apparently Cowboys owner Jerry Jones’ plan all along – to follow the Cleveland Browns’ recipe of using dual running backs instead of one so both are fresh in the fourth quarter, something that’s working to near perfection with Zeke Elliot and Tony Pollard.

In the past, Elliott typically got the most carries for Dallas, the dual-threat playmaker scary from out of the backfield and in the flat, so far this year with 51 total touches for 252 yards from scrimmage and 3 touchdowns, a production that comes from being better-rested thanks to sharing his rushing duties nowadays.

Zeke’s partner is running back Tony Pollard, now in his third NFL season (all with Dallas), the young back so far with 27 carries in 2021 (Zeke’s had 17) for 183 yards and a touchdown all while giving his ‘aging’ 26-year-old counterpart a few seconds now and then to rest.

Editor’s Picks

Panthers Key Player: (RBs) Chuba Hubbard & Royce Freeman

Without an injured Christian McCaffrey on the field, the Panthers must scramble to fill his huge shoes, so that duty goes to backup running backs Chuba Hubbard and Royce Freeman as well as whichever receiver best lines up in the slot.

Hubbard is an NFL rookie who played college ball at Oklahoma State where he was the Big 12 Offensive Player of the Year in 2019, and now as a pro, he has 19 carries for 62 yards plus 5 catches for 31 yards for Carolina with no end-zone visits so far.

Also needing to pitch in is Royce Freeman, a back that Carolina picked up off waivers in early September, a fourth-year player who started his career in Denver where he played in all but two games and scored 8 times.

Cowboys Key Player: (LB) Micah Parsons

The Cowboys got lucky in the draft this offseason when they selected Micah Parsons in the first round (12th overall), the 6’ 3 1/8” 246 pound Penn State linebacker who is already making quite a name for himself in the NFL.

All eyes are on him in 2021, expectations high and so far met by this young playmaker, with 1.5 sacks, 6 quarterback hits, 2 passes defended and 13 total tackles already, his closing speed causing fans and opposing offenses to shake their heads.

Parsons is all part of the upgraded defense made possible in part by the leadership of new defensive coordinator Dan Quinn, the former Atlanta Falcons head coach and Super Bowl Champion who was brought in by Cowboys owner Jones to improve their shaky D.

How to Watch Panthers vs Cowboys

Panthers vs Cowboys Information
Teams Carolina Panthers vs Dallas Cowboys
Location AT&T Stadium in Arlington, Texas
Time Sunday, October 3, 2021; 1:00 PM ET
How to watch FOX

Play Fantasy Football Here!

Logo #1



Bet $5, Get $200 in Bonus Bets

21+ | Terms and conditions apply

Logo #2



$500 Bonus Bet

21+ | VA only | Gambling problem? Call 1-800-532-3500

Image for Mike Lukas

Mike Lukas

Sports Betting & Gambling Industry Analyst

Gambling News
Betting Picks
Mike Lukas is a retired standup comedian turned freelance writer now living in Dallas, Texas, originally from Cleveland, Ohio. His love for the game of football and all things Cleveland Browns turned Mike into a pro blogger years ago. Now Mike enjoys writing about all thirty-two NFL teams, hoping to help football gamblers gain a slight edge in their pursuit of the perfect wager.
Nationality: American
Education: N/A
Favourite Sportsbook: bet365 Sportsbook
Favourite Casino: Caesars Palace Casino
23 years
We've been featured on:
espn logo
reuters logo
cbs-news logo
forbes logo
entrepreneur logo
entrepreneur logo
We only list licensed sportsbooks

© Rebel Penguin ApS 2024 (a subsidiary of Gaming Innovation Group Inc.)

We support responsible gambling. 21+ Only. Gambling problem? Call 1-800-Gambler.

WSN.com is run by iGaming Cloud Inc (a Gaming Innovation Group Subsidiary) and is registered with the New Jersey Division of Gaming Enforcement (DGE) under affiliate vendor ID 89744, with the Indiana Gaming Commission (IGC) under certificate of registration number SWR-000148, approved by the Pennsylvania Gaming Control Board as a gaming service provider, under certificate registration number 117656-1, possesses a Vendor Minor sports betting license from the Colorado Limited Gaming Control Commission (account number 94414163), granted a vendor registration number VR007603-20-001 by the Michigan Gaming Control Board, an interim Sports Wagering Supplier license, under license number SWS 066, issued by the West Virginia Lottery Commission, a sports betting vendor registration, under registration number #100400, issued by the Director of Gaming Licensing and Investigations of the Virginia Lottery to operate in the State of Virginia, and a Vendor Registration issued by the Sports Wagering Committee of the Tennessee Education Lottery Corporation.

Advertising disclosure: WSN contains links to online retailers on its website. When people click on our affiliate links and make purchases, WSN earns a commission from our partners, including ESPN and various sportsbooks.