NFL Week 12 Picks Against the Spread [2020]

• Get the most recent odds for NFL Week 12 Games in 2020
• Our top predictions and picks for the season’s twelfth week of games
• View stats from past seasons to help give you an edge over the sportsbooks

Week 12 of the NFL’s 2020 season begins with a Turkey Day tripleheader that includes the possible game of the week, and AFC North between the still undefeated Pittsburgh Steelers and the Baltimore Ravens, a battle that could help decide one of the three Wild Card spots in that conference.

This week also includes an exciting showdown between two quarterback greats, young and old, when quarterback Patrick Mahomes and his Kansas City Chiefs travel to Florida to take on the GOAT Tom Brady and his Tampa Bay Buccaneers, a cross-conference game that will no doubt include some fun offense.

Injuries and COVID scares have made this season even more challenging than usual, and as we begin the final stretch towards the postseason, the teams on the playoff cusp begin to play with a bit more immediacy and in some cases, desperation.

Here are our Week 12 picks against the spread – good luck!

Week 12 Thanksgiving Games, Thursday, November 26

Houston Texans (-2.5) vs Detroit Lions

How to watch: Thursday, 12:30 PM ET, CBS

The Texans finally managed their third win of the season in Week 11 over the Patriots, final score 27-20, and QB Deshaun Watson connected with two different receivers for touchdowns with no picks while the defense kept New England to just a field goal in the fourth quarter.

The 4-6 Lions got shut out by the Panthers in Week 11, with QB Mathew Stafford completing 18 passes for just 178 yards with zero touchdowns and a passer rating of just 70, the team’s rushing attack equally impotent with all of their running backs posting less than 20 yards of rushing.

The Texans are slightly favored here, and as inconsistent as they have been, at this point, the Lions are less dependable.

Pick:

Texans -2.5   (-110)

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Washington Football Team vs Dallas Cowboys (-3)

How to watch: Thursday, 4:30 PM ET, FOX

It is a true pleasure to watch Washington QB Alex Smith back under center, the veteran hurler finally healthy and leading his Football Team to their third victory of the season over the Bengals, 20-9, with Washington’s defense able to keep Cincinnati off the scoreboard in the second half.

Cowboys also notched their third victory of the season last week by beating the Vikings, outscoring them in the fourth quarter by a point and taking the win, 31-28, their temporary QB Andy Dalton looking like the veteran he is with 3 passing touchdowns and an interception in the win.

Washington has a stronger defense than Dallas, at least right now, but the Cowboys look far stronger on offense and should cover the spread at home.

Pick:

Cowboys -3   (-107)

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Week 12 Sunday Games, November 29

Las Vegas Raiders (-3) vs Atlanta Falcons

How to watch: Sunday, 1:00 PM ET, CBS

In an exciting Week 11 Sunday Night Football matchup with the Chiefs, the Las Vegas Raiders came close to a win, their defense giving up a last-minute touchdown in a game that saw both teams ahead at different points, and QB Derek Carr is finally looking like his HC Jon Gruden is getting through to him and now he is playing excellent football.

QB Matt Ryan threw two interceptions in the Falcons Week 11 loss to the New Orleans Saints (who weren’t even fielding their starting quarterback), and the 3-7 Falcons are all but done for this season, especially after these talented Raiders take care of them here.

The Raiders are figuring out who they are on both sides of the ball and the Falcons will most likely find out the hard way in Week 12.

Pick:

Raiders -3   (-110)

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Los Angeles Chargers vs Buffalo Bills (-5.5)

How to watch: Sunday, 1:00 PM ET, CBS

It was a close win for the Chargers in Week 11 over the winless Jets, final score 34-28, and it will be a much larger uphill climb for Week 12 as they face these well-rested Bills, so the freshly quaffed LA QB Justin Herbert gets to put on another show like he did last week, hopefully, when he posted 366 passing yards for 3 touchdowns and no picks in that victory.

It must have been a long week off for the 7-3 Buffalo Bills, first miraculously losing to the Cardinals in the very last seconds of Week 10 by a narrow score of 30-32, so now they must face a Chargers team that is fresh off a win and now QB Josh Allen gets to keep his team playoff-worthy against these shaky Chargers.

The Bills must prove they are postseason contenders and a win over these Chargers is a great way to start.,

Pick:

Bills -5.5   (-110)

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New York Giants (-5.5) vs Cincinnati Bengals

How to watch: Sunday, 1:00 PM ET, FOX

The New York Giants enjoyed some Week 11 rest on their bye, and that gave them a chance to bask in the glow of their third win, a Week 10 victory over the division-leading Eagles, and now young QB Daniel Jones gets a chance to post another win against these injury-plagued Bengals.

In one of the biggest disappointments of the season, the Cincinnati Bengals lost their rookie starting quarterback Joe Burrow for the year to a brutal torn ACL and now they find themselves right back to where they were before they scored one of the brightest young players in the league, and that’s as a minimally talented young franchise that still needs plenty of pieces on both sides of the ball.

Tough to imagine the Bengals have what it takes now to beat these Giants, even though neither team is very competitive this season.

Pick:

Giants -5.5   (-110)

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Tennessee Titans vs Indianapolis Colts (-3.5)

How to watch: Sunday, 1:00 PM ET, CBS

The Tennessee Titans are 7-3 and in second place of the AFC South behind these Colts, so this becomes a must-win if the Titans expect to see the playoffs as a divisional winner, and the way the AFC is shaping up right now, that would be a better route to the postseason for them than counting on a Wild Card spot over a lot of other talented 7-3 teams.

The Colts defense is impressive, and they showed off their skills in an overtime Week 11 win over the incredibly talented Green Bay Packers, keeping their offense out of the endzone in the second half and in overtime and solidifying their seventh win of the season.

The Colts defense could be too much for the Titans despite another productive game from Henry.

Pick:

Colts -3.5   (-110)

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Carolina Panthers vs Minnesota Vikings (-4.5)

How to watch: Sunday, 1:00 PM ET, FOX

Nobody expected the Panthers to do as well as they did missing their starting QB Teddy Bridgewater and star RB Christian McCaffrey, but they still got the Week 11 win with Mike Davis carrying the ball 19 times for 64 yards and a touchdown while QB P.J. Walker took care of business under center, throwing for 258 yards and a touchdown, earning the victory despite his two interceptions.

Didn’t seem possible, but the Dalvin Cook enhanced Vikings lost to the Dallas Cowboys and now the team sits at 4-6 and in serious trouble when it comes to making the playoffs, their QB Kirk Cousins throwing a masterful game in that defeat, going 22-of-30 for 314 yards and 3 touchdowns with no interceptions.

If the Panthers can play the way they did in Week 11, backups and all, they could find a way to beat these Vikings, especially with the points.

Pick:

Panthers +4.5   (-110)

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Arizona Cardinals (-2.5) vs New England Patriots

How to watch: Sunday, 1:00 PM ET, FOX

The Cardinals are 6-4 now after a loss to the Seahawks in Week 11, a game where quarterback Kyler Murray completed 29 passes for 269 yards and 2 touchdowns with no interceptions, but their normally top-notch rushing attack fell short and failed to give their offensive game plan the type of balance it needs to be effective.

The New England Patriots are shaky this season despite having enough talent to get four wins, and to get their fifth in Week 12 against these Cardinals they better hope that quarterback Cam Newton is ready to have the kind of production he had in their Week 11 loss – 26/40 for 365 yards, 1 TD 0 INT.

Take the Cardinals against this up and down Patriots offense.

Pick:

Cardinals -2.5   (-110)

Odds from DraftKings. Get up to a $1,000 sign-up bonus at DraftKings today or check out more offers and promo codes for the best online sportsbooks.

Miami Dolphins (-6.5) vs New York Jets

How to watch: Sunday, 1:00 PM ET, CBS

Supposedly Dolphins rookie QB Tua Tagovailoa will get the start in this one despite being benched for backup Ryan Fitzpatrick in the team’s Week 11 loss to the Broncos, the kid still managing to throw a touchdown with no interceptions in the loss, a good sign that he can be effective this early.

The Jets have still not won a game in 2020, and at 0-10 they do not look likely to beat these Dolphins, with QB Joe Flacco getting a chance under center again, his Week 11 numbers showing promise despite the loss, posting 15 completions for 205 yards and 2 touchdowns with an interception.

Regardless of who is under center for the Phins, it would be silly to start betting on the Jets at this point.

Pick:

Dolphins -6.5   (-110)

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Cleveland Browns (-6.5) vs Jacksonville Jaguars

How to watch: Sunday, 1:00 PM ET, CBS

This season, the 7-3 Cleveland Browns are finding ways to win the games they should, and this Week 12 matchup with the less talented Jaguars is one of those, so QB Baker Mayfield and company will finally get a chance to flex their skills in decent Florida weather after spending weeks in the wind and rain winning at home.

The Jacksonville Jaguars looked great against the undefeated Pittsburgh Steelers for a few moments when they led the game 3-0 after the first quarter, but then it was all over and the final score of 3-27 tells you everything you need to know about the Jags on both sides of the ball, their rookie QB Jake Luton sacked twice while throwing four interceptions in the loss.

The Browns should take care of this Jaguars team whose offense only scores an average of 20 points per game.

Pick:

 Browns -6.5   (-110)

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Baltimore Ravens vs Pittsburgh Steelers (-4.5)

How to watch: Sunday, 1:15 PM ET, NBC

The Baltimore Ravens were kept out of the end zone in the second half of their loss to the Titans in Week 11 and quarterback Lamar Jackson was not able to hurt them the way he typically does on the ground and through the air, while the defense allowed Tennessee’s main rusher, Derrick Henry, to earn 133 yards and a touchdown.

The Steelers offense started slowly in Week 11 but once again their defense took charge of the game and kept the Jaguars to just a field goal while QB Ben Roethlisberger and company got busy in the second quarter and scored 17 of their 27 points on their way to the team’s tenth win.

At some point, these Steelers have to lose, but the Ravens couldn’t beat them at home in Week 8 and most likely won’t in Week 12 at Heinz Field.

Pick:

Steelers -4.5   (-110)

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New Orleans Saints (-5.5) vs Denver Broncos

How to watch: Sunday, 4:05 PM ET, FOX

Even without QB Drew Brees under center, the Saints found a way to win in Week 11 with backup Taysom Hill getting the start and proving that he has the legs and the arm to get the job done, completing 18-of-23 for 233 yards and 2 rushing touchdowns in this critical victory.

The Denver Broncos played so well in Week 11 that their opponents, the Miami Dolphins, benched their rookie starting QB and went with their backup, with Broncos QB Drew Lock having his own challenges with an interception and no touchdown passes in the game.

The Saints have proven they can win without Brees, and Hill is just getting warmed up, so Denver should not be a problem.

Pick:

Saints -5.5   (-110)

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San Francisco 49ers vs Los Angeles Rams (-6.5)

How to watch: Sunday, 4:05 PM ET, FOX

The 49ers took a tough Week 10 loss to the Saints, and then they got to think about it over their Week 11 bye, and now things don’t get any easier for QB Nick Mullens as he does his best to fill in for injured starter Jimmy Garoppolo, Mullens last outing a one touchdown two-interception affair.

It was a close win for the Rams on Monday Night Football, a game that only took a field goal in the final minutes to seal the deal against Tom Brady’s Buccaneers, final score 27-24, and now Los Angeles has the chance to snag another divisional victory against these less than healthy 49ers.

The Rams seem to have the roster in place to take care of these shaky Niners.

Pick:

Rams -6.5   (-110)

Odds from DraftKings. Get up to a $1,000 sign-up bonus at DraftKings today or check out more offers and promo codes for the best online sportsbooks.

Kansas City Chiefs (-2.5) vs Tampa Bay Buccaneers

How to watch: Sunday, 4:25 PM ET, CBS

You can bend these 9-1 Chiefs, but it is tough to break them, especially twice in the same season as the Raiders found out in Week 11, Kansas City scoring in the final minutes of the fourth quarter to secure the victory, 35-31, with QB Patrick Mahomes looking excellent despite a pick, completing 34 passes for almost 350 yards and two touchdowns.

GOAT Tom Brady threw two touchdowns and two interceptions in the Buccaneers’ Monday Night Football loss to the LA Rams, final score 24-27, giving Tampa Bay a 7-4 record and keeping them a game behind the Saints in the NFC South, nothing a big upset win over these excellent Chiefs won’t help cure.

At this point, it is difficult to put much faith in the Chiefs losing any more games, so take them over these talented Bucs in Week 12.

Pick:

Chiefs -2.5   (-110)

Odds from DraftKings. Get up to a $1,000 sign-up bonus at DraftKings today or check out more offers and promo codes for the best online sportsbooks.

Chicago Bears vs Green Bay Packers (-7.5)

How to watch: Sunday, 8:20 PM ET, NBC

The Bears enjoyed a Week 11 bye, a much-needed respite from their Week 10 loss to the divisional rival Vikings on Monday Night Football, final score 13-19, and now QB Nick Foles must decide if he is, indeed, the man who can turn this 5-5 franchise around enough to play football in January.

Not often that Packers QB Aaron Rodgers throws for 3 touchdowns and Green Bay loses, but that’s what happened in Week 11 against the Colts in overtime, 31-34, with the Packers run game struggling to excel, Aaron Jones with just 10 carries for 41 yards and a touchdown, his longest a 15-yarder.

The Packers are the real deal, and they will be facing the Bears with several giant chips on their collective shoulders.

Pick:

Packers -7.5   (-110)

Odds from DraftKings. Get up to a $1,000 sign-up bonus at DraftKings today or check out more offers and promo codes for the best online sportsbooks.

Week 12 Monday Night Football on November 30

Seattle Seahawks (-5) vs Philadelphia Eagles

How to watch: Monday, 8:15 PM ET, ESPN

Another win for one of the many talented 7-3 teams, the Seattle Seahawks, would help them stay in charge of the NFC West, and chances are they are going to get it against this Eagles team that can’t seem to stop stepping on their own feet, with penalties and turnovers their worst enemy right now.

Talk about a must-win game, the Philadelphia Eagles are barely holding onto the horribly untalented NFC East and a loss here would allow the Dallas Cowboys the chance to surge ahead, but if the Eagles don’t start protecting QB Carson Wentz (40 sacks, most in the league) then they may not have him under center in playoffs regardless.

Seattle’s defense is not good right now, but they should be good enough to keep the Eagles from outscoring them on Monday Night Football.

Pick:

Seahawks -5   (-110)

Odds from DraftKings. Get up to a $1,000 sign-up bonus at DraftKings today or check out more offers and promo codes for the best online sportsbooks.

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