This week’s Thursday Night Football game pits the New York Giants against the San Francisco 49ers. While this contest has the potential to be a serious mismatch given the way these teams have started the year, there are no shortage of betting angles to take. Here, we break down our top Thursday Night Football prop bets for this Week 3 matchup from Santa Clara.
Our first Thursday Night Football prop bet for this week is for Brandon Aiyuk to score a touchdown at +155. Aiyuk has been an ever-present weapon for the 49ers so far this season, and he is going to continue to give teams trouble this week. At a better price than some of the other scoring options for the Niners, Aiyuk is worth a look, as he aims to build on his strong start to the season.
Looking at the anytime touchdown scorer markets for this game, Christian McCaffrey and Deebo Samuel both come in at worse prices than Aiyuk to score. McCaffrey is at a jaw-dropping -190 to score in this game at DraftKings, while Samuel sits at +120. But Aiyuk has the same number of touchdowns as McCaffrey on the season and has one more than Samuel so far.
Playing Aiyuk is also a play based on the lack of depth in the secondary for the Giants at this point in the season. The Giants are respectable at the first couple of corner spots, but things go off a cliff pretty quickly from there for Brian Daboll’s team. Expect Aiyuk to take advantage and to score at least once in this contest.
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Next on our list of Thursday Night Football prop bets is Daniel Jones to go over his rushing yardage total of 39.5 yards. There are several reasons this prop is worth betting on, from the injuries facing this Giants team to the personnel matchups they face against the 49ers defense. All of it should add up to at least 40 rushing yards for Jones when this game is in the books.
Jones and the Giants could be without Saquon Barkley for this game, who suffered an injury last week against the Arizona Cardinals. With a less impactful traditional running game, the Giants will then have to get more resourceful to move the ball on the ground here, which will mean more designed runs for Jones. Jones will also have to scramble to get away from a 49ers pass rush that has been tenacious already in 2023.
It is also worth noting that this is pro football, and not college football, where sacks count as negative rushing yardage. Jones will get to keep all of his rushing yards, even if he gets sacked early and often by a 49ers team that already has six sacks through two games.
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The final Thursday Night Football prop bet on our radar for this week is for the Giants to score under 16.5 points as a team. So far this season, the Giants have scored a total of 31 points through two games. Those all came in the second half of a comeback win against an Arizona Cardinals team that could go down as one of the worst NFL teams in recent memory, and the Giants will struggle even more against one of this year’s Super Bowl favorites.
On the flip side, the 49ers have allowed a total of 30 points through two games, a number that would be even lower had the LA Rams not kicked their infamous last-second field goal that did nothing to impact the outcome of last week’s game. San Francisco’s defense has been incredibly stingy, and there is no reason to believe that will change against a Giants team that has already been shut out once this year.
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