When you sign-up through links on our site, we may earn an affiliate commission. Learn more >

Best 49ers vs. Jaguars Prop Bets NFL Week 10

Written by: Richard Janvrin
Published November 12, 2023
8 min read
49ers vs Jaguars Predictions

One of the more fascinating games this week comes from two teams coming off of a bye week: the San Francisco 49ers and Jacksonville Jaguars. The 49ers are in the middle of a three-game losing streak, while the Jaguars have a hold on the AFC South.

Below are the three best bets for this matchup.

San Francisco 49ers vs. Jacksonville Jaguars

Pick: Travis Etienne Under 3.5 Receptions (-120) at DraftKings

In this matchup, Etienne will take on a 49ers defense that allows about five receptions for 34 yards and 0.12 touchdowns per game to opposing running backs.

This season, Etienne has lived on the hook of this 3.5 line, catching three passes in a game four times and four passes twice, and the other two games were a five-catch day (Week 1) and two catches (Week 2). 

Etienne is their primary pass-catcher out of the backfield. Still, he’ll also face 49ers run defense that’s been somewhat generous to running backs, allowing over four yards a carry but just 64 yards per game. They’ve allowed 93 or more in two of their last three games. 

The 49ers perform worse against wide receivers, allowing 12 receptions for 175 yards and a touchdown per game, so Lawrence may have more looks to them and further down the field. 

We think Etienne finishes with three or fewer receptions here. 

Get $200 in bonus bets when you wager $5 at DraftKings Sportsbook when you sign up using our exclusive link

Pick: Trevor Lawrence Under 16.5 Rushing Yards (-115) at DraftKings

The 49ers added a new pass rusher in Chase Young to go alongside Nick Bosa, so Lawrence will be contending with that all afternoon. 

This season, Lawrence has 216 rushing yards, averaging 27 per game. However, the 49ers don’t exactly allow quarterbacks to pick up yardage on the ground. 

The 49ers allow four carries and 15 yards rushing per game to opposing quarterbacks. Also, that 15-yard average includes two games where Joshua Dobbs had 48, and Joe Burrow somehow managed 43. 

If you take those games away, the average drops to less than five yards per game. 

This will be more of a pocket-focused game for the former No. 1 overall pick. 

Wager just $5 at DraftKings and get $200 in bonus bets

Pick: Trevor Lawrence Over 0.5 Interceptions (-119) at Caesars

Sticking with Lawrence, we think he’s good for an interception in this one. This season, he has four interceptions but 11 turnover-worthy plays. Against the 49ers, he’ll face a defense that allows 26 completions on 39 attempts to opposing quarterbacks for 244 yards, 1.25 touchdowns, and 1.38 interceptions. 

The 49ers have just two games without an interception and have four games with multiple. 

We expect the 49ers to get back on track here, and the added pass rush from Young should help make the day more difficult for Lawrence. 

Get a bonus bet of up to $1,000 at Caesars Sportsbook when you click our exclusive link and use promo code “WSN1000.”

*All statistics courtesy of Pro Football Focus.

More Sportsbook Promos

More NFL Week 10 Stories

Image for Richard Janvrin


Richard Janvrin

550 Articles

After graduating from the University of New Hampshire with a BA in Journalism, Richard Janvrin has been covering iGaming and sports betting since December 2018. Richard has covered betting at Bleacher Report, Gambling.com, The Game Day, Forbes, and more.

More info on Richard Janvrin
We've been featured on:
espn logo
reuters logo
cbs-news logo
forbes logo
entrepreneur logo
entrepreneur logo
We only list licensed sportsbooks

© Rebel Penguin ApS 2024 (a subsidiary of Gaming Innovation Group Inc.)

We support responsible gambling. 21+ Only. Gambling problem? Call 1-800-Gambler.

WSN.com is run by iGaming Cloud Inc (a Gaming Innovation Group Subsidiary) and is registered with the New Jersey Division of Gaming Enforcement (DGE) under affiliate vendor ID 89744, with the Indiana Gaming Commission (IGC) under certificate of registration number SWR-000148, approved by the Pennsylvania Gaming Control Board as a gaming service provider, under certificate registration number 117656-1, possesses a Vendor Minor sports betting license from the Colorado Limited Gaming Control Commission (account number 94414163), granted a vendor registration number VR007603-20-001 by the Michigan Gaming Control Board, an interim Sports Wagering Supplier license, under license number SWS 066, issued by the West Virginia Lottery Commission, a sports betting vendor registration, under registration number #100400, issued by the Director of Gaming Licensing and Investigations of the Virginia Lottery to operate in the State of Virginia, and a Vendor Registration issued by the Sports Wagering Committee of the Tennessee Education Lottery Corporation.

Advertising disclosure: WSN contains links to online retailers on its website. When people click on our affiliate links and make purchases, WSN earns a commission from our partners, including ESPN and various sportsbooks.