AFC South Odds, Predictions, Best Picks 2025: Can the Texans Protect CJ Stroud?

• The Texans have won the division in the last two seasons

• Travis Hunter is expected to start at receiver for the Jags

• The Colts signed Daniel Jones to back up Anthony Richardson

The AFC South may not be pretty, but it is expected to be one of the closest division races in the league. The Texans have won the last two titles and enter the 2025 season as the favorites to win another. However, they’ll face a group of division rivals that have improved in the offseason. 

Below, we’ll preview the AFC South heading into the 2025 season. We’ll discuss how we see the 2025 season play out and our pick to win.

AFC South Odds

Odds from Caesars Sportsbook. Use our promo code WSNDYW to sign up for a Caesars account and claim the welcome offer: Bet $1, Get 10 100% Profit Boost Tokens.

AFC South Predictions

We are very excited to see Travis Hunter in the lineup alongside Brian Thomas Jr. for the Jags this season, but we don’t have high hopes for this team. A tumultuous offseason saw them bring in a new coach, apparently at the expense of their GM. That means they have overhauled the front office and coaching staff, making it hard to know what to expect.

The Colts may be the most interesting team to watch in the division. We love the roster they are building, but the quarterback position remains a significant concern. We saw Anthony Richardson’s impressive ceiling last season, but also got a taste of where his floor is. He was temporarily benched last season and will now have Daniel Jones sitting behind him on the depth chart. If Indy can’t get production from the duo, expect them to see another disappointing season.

The Titans enter as an appealing longshot to win the AFC South with rookie Cam Ward at quarterback. The team bolstered its roster in the offseason, including upgrading their terrible offensive line. With a young quarterback who excels at escaping pressure and improved protection, this Tennessee offense could be set to explode in 2025.

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AFC South Winner - My Pick

Texans (+110) at BetMGM Sportsbook

Houston has fantastic defense and one of the best young quarterbacks in the league. Injuries and struggles to protect CJ Stroud took their toll last season, but the team hopes offseason changes will fix that. If they can protect Stroud, this is a team that will compete for Super Bowl LX.

Even if Houston runs into these familiar problems, we still think they are better than the other three teams in a weak AFC South.

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How to Bet on the AFC South

Betting on the AFC South is a fairly simple task for bettors of all backgrounds, but learning where to find and place these bets can take time. If you find yourself stuck, we have you covered. 

Here is an easy step-by-step guide to help you get started:

1. Choose the sportsbook you want to wager with

2. Select “Football” or “NFL” from the betting catalog, usually found on the top or side menu

3. Click on the tab for “Futures”

4. Read through the options for the “Division Winner” section

5. Scroll down until you find the AFC South

6. Select the team you think will win

7. Navigate to your betslip to enter how much you want to wager

8. Hit submit, and you are all set!

All division futures bets will be paid out once the season ends and a champion is officially crowned. 

How to Read AFC South Odds

NFL futures odds work the same as any other bet. Each bet includes a number following the team or player, preceded by a plus or minus sign. 

A plus sign before the number usually indicates an underdog, which is common with futures bets. If the odds next to a team or player have a plus sign, that is the amount that you will win for every $100 you bet.

A minus sign usually indicates the favorite to win, though they are rarely seen for future bets. A minus sign in front of the odds means that is how much you need to bet to win $100.

For example, you bet $100 on the Texans at +110 to win the AFC South. If they win the division, you will win $110. 

If you aren't looking to bet $100 at a time, don't worry! Check out our odds calculator to help you determine potential winnings based on different wager amounts.

Where to Bet on the AFC South

Are you ready to start betting on the AFC South but unsure where to start? If so, we have you covered with our sportsbook reviews. Here are our three favorite sportsbooks we use when betting on NFL futures:

• BetRivers Sportsbook: This sportsbook has been one of the few success stories from mid-size operators in the US. The platform isn’t as sharp as FanDuel or BetMGM, but it offers bettors some fantastic bonuses and very competitive odds. If you are looking for a smaller and more player-friendly platform, we highly recommend BetRivers. Follow our link to claim the promo offer: $500 Bonus Bet.

• FanDuel Sportsbook: If you are betting on America’s favorite sport, why not use its favorite sportsbook? FanDuel offers bettors an easy-to-use platform that is easy to navigate. The odds, promotions, and rewards are unmatched, meaning you can have more money in your pocket when you win. Use our link to register and claim the promo offer: Bet $5, Get $200 in Bonus Bets if Your Bet Wins.

• Caesars Sportsbook: Caesars offers one of the best NFL betting experiences in the industry. The Las Vegas sportsbook has a flashy platform that lets you easily find games, place wagers, and follow your bets. Caesar’s also offers the ability to live stream most NFL games from their app, allowing you to watch games on the go. Use our promo code WSNDYW and claim the following offer: Bet $1, Get 10 100% Profit Boost Tokens.

AFC South Winner History

The Texans won their second consecutive AFC South title in 2024. Caesars has the Texans as an early favorite to win another in 2025, but they’ll face an improved division.

Below are the last ten teams to win the AFC South.