NFL Most Sacks Leader Predictions, Picks, Best Bets 2025: Trey Hendrickson Contract Dispute Lingers

• Los Angeles Rams edge rusher Jared Verse led the league in pressures in 2024 with 89. 

• Cleveland Browns edge rusher Myles Garrett signed a four-year, $160 million contract extension with the team in March. 

• Detroit Lions edge rusher Aidan Hutchinson fractured his tibia and fibula last season after recording 7.5 sacks in five games. 

The 2025-26 NFL season is quickly approaching. The Hall of Game game kicked off the preseason on July 31. 

With that, now is a great time to look at some NFL futures betting markets, including who will lead the league in sacks. 

The 2024-25 sack leader, Trey Hendrickson of the Cincinnati Bengals, was holding out for a new deal, but has since reported to training camp just before July ended. 

Below, we’ll look at the top odds-on favorites, provide three best bet options, my final pick, and more.

2025 NFL Most Sacks Odds

Odds courtesy of Caesars Sportsbook. Sign up for a new account at Caesars with our promo code WSNDYW and claim the following welcome offer: Bet $1, Get 10 100% Profit Boost Tokens.

2025 NFL Sacks Leader Predictions

The best time to wager on NFL futures markets is before the season, as value can diminish once stats are recorded. 

Below are three options I’d consider: 

• Aidan Hutchinson: Coming off a fractured tibia and fibula, there’s obvious concern with Hutchinson, but you cannot deny the dominance he’s displayed when he’s on the field. He played in all 17 games as a rookie and in his second season. He had 7.5 sacks over five games before the injury. He’ll be heavily relied on for the Lions and on the field plenty. 

• Jared Verse: As a rookie, Verse recorded just 4.5 sacks. That said, he led the league in pressures with 89. That’s quite a disparity between pressures and sacks. If he can finish those pressures and turn them into sacks, he has a chance to run away with the sack title in just his second year in the NFL. 

• Myles Garrett: Garrett finished with 14 sacks in 17 games. He also recorded 83 pressures, tied for the fourth-most in the NFL. He has a new massive contract and is a tried-and-true veteran who always has the potential to lead the league in sacks. He’s one of the most dominant defensive linemen of this generation. 

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My NFL Sacks Leader Pick - Jared Verse

I’m balancing value with upside here. Verse didn’t have many sacks as a rookie, but again, he was only a rookie. He racked up 89 pressures, and he’s on a defense that has multiple players who can wreak havoc and help open up lanes for Verse to tee off. I expect a massive leap forward in the sack department for Verse this season. 

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How to Bet on the NFL Sacks Leader

In addition to the futures betting market for who will lead the league in sacks, many of the top online sportsbooks provide prop bets for sacks each game, and there are futures markets available with over/under lines for individual players. 

For example, you can wager on Nick Bosa’s line of 10.5 sacks at Caesars Sportsbook.

How to Read NFL Sacks Leader Odds

When examining NFL odds for the sack leader or any other market, you’ll come across “+” odds and “-” odds. 

When you see “-” odds, these are players more likely to succeed, and the larger the number, the more likely it is. For example, if a player is -1000, they’re more likely, odds-wise, than a player that’s -500. 

As for “+” odds, it goes the other way; the larger the number, the more unlikely the player is. If a player is +1500, they’re less likely to succeed than a player who’s +1000. 

Now, let’s examine these odds through the lens of winning $100 or wagering $100.

• “+” odds indicate how much you’d win on a $100 bet. For instance, if Verse is listed at +1500, a $100 wager would return $1500 in winnings.

• “-” odds show how much you must bet to win $100. So, if Verse were -1500, you’d have to wager $1500  just to win $100.

Where to Bet on NFL Sacks Leader

There are many excellent online sportsbooks to wager on the NFL sacks leader, including the following: 

• Caesars Sportsbook was the first sportsbook to release these preseason odds. It features a new player-friendly welcome bonus with boosted bets, as well as regular odds boosts and live streaming of select NFL games. Use our promo code WSNDYW to sign up for an account and claim the following offer: Bet $1, Get 10 100% Profit Boost Tokens.

• FanDuel Sportsbook provides a generous welcome bonus: Bet $5, Get $150 in Bonus Bets if Your Bet Wins. On top of that, FanDuel offers excellent customer support and helpful tools to guide new bettors through the sports betting experience.

• BetMGM Sportsbook has a massive welcome bonus, too, and includes free-to-play games that can earn players bonus bets. Sign up for a BetMGM account with our promo code WSNSPORTS to be eligible for the welcome offer: Get Up to $1,500 in Bonus Bets*.
  
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NFL Sacks Leader History

Sacks have been tracked in the NFL since 1960, less than a decade before today’s “Super Bowl era.” 

Below is the NFL's sack leader every year since 2010. Steelers edge rusher T.J. Watt led the league in sacks three times from 2020 to 2023.