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Atletico San Luis vs. Club America Prediction: Las Aguilas Eye Redemption in Upcoming Match

Published: September 23, 2025, 11:00 AM ET
4 min read
  • San Luis is off to a moderate first-half in the Apertura campaign, victors in three of their first nine 

  • Club America have failed to secure a maximum result in two consecutive 

Wednesday evening, Liga MX powerhouse Club America will head down to Estadio Alfonso Lastras to clash against Atlético San Luis. The previous encounter saw Las Aguilas win comfortably during the 2025 Clausura regular season, winning by three goals. 

Here, we will break down the betting odds and share our favourite picks for Atletico San Luis vs. Club América.

Atletico San Luis vs. Club America Betting Odds for Wednesday, September 24

The manufactured odds for this tilt see the visitors pegged as the favourites to collect all three points. Las Aguilas are priced at -148 to win while San Luis is listed at +330. If both sides are level after the final whistle, the draw is logged down at +300.

Atletico San Luis vs. Club America Odds

The odds for Atletico San Luis vs. Club America can be found in the odds table below, courtesy of BetRivers sportsbook. Sign up for a BetRivers account and claim Up To $500 In Bonus Bets.

Moneyline 3-wayOdds
Atletico San Luis+330
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Draw+300
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Club America -148
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Atletico San Luis vs. Club America 2025 09 24

Atletico San Luis vs. Club America Betting Prediction

Atletico San Luis Preview

Sunday evening, Guille Abascal's men won a lopsided affair on the road, beating Santos Laguna 4-1. With the triumph, San Luis moved up to 11th place in the table, garnering 10 points through nine contests. The offensive explosion against Santos was only the second occurrence where San Luis were able to breach the keeper on three or more occasions.

Voted the player of the match on Sunday, Joao Pedro continues to perform at a high level in his debut season in Liga MX. The 33-year-old striker has scored eight goals in nine league appearances, including three multi-goal showings. Pedro could be lively on Wednesday, as he is averaging 1.73 shots on target per 90.

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Club America Preview

Andre Jardine's troops have returned to reality after their four-game win streak came to a halt. Over the weekend, Club America battled back from being down a pair of goals to finish level in a 2-2 draw thanks to some late-game heroics against C.F. Monterrey. With the stalemate, Las Aguilas registered their 18th point in the Apertura.

Subbing on in the half, Rodrigo Aguirre managed to find the back of the net against his former employers, snapping a five-game scoreless run in the top-flight division. Allan Saint-Maximin, in his second consecutive start, failed to obtain a goal or an assist. The 28-year-old was unlucky to go home empty-handed as he finished his outing on Saturday with the most chances created in the match, with six.

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Atletico San Luis vs. Club America - My Pick

Midweek fixtures can cause chaos with the unexpected coming to fruition; that said, we feel Club America can put their mini-slump at a standstill. The visitors are squaring off against a side that has yet to win in consecutive matches this term. Historically, Club America has found success playing on Estadio Alfonso Lastras' soil, winning on 10 occasions in their previous 13 trips. Heading into Wednesday's clash, the hosts will have the disadvantage of playing on one day's shorter rest. Club America will be chomping at the bit to get back into the win column, which we sense they're in a favourable spot to do so.

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How to Watch Atletico San Luis vs. Club America

  • When: September 24, 11 p.m. ET

  • Where: Estadio Alfonso Lastras 

  • TV: Univision, UniMás, TUDN, ViX

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Angelo Zarra WSN Contributor

Angelo Zarra

Soccer Betting Analyst

Expertise:
MLS
Liga MX
Betting Picks
Hailing from the great white north in Canada, over the last 15 years, Angelo has been wagering on sports and, more specifically, the sport that’s in his blood, soccer. Well-versed in soccer leagues across the globe, keeping tabs on what’s happening in the world of soccer. Since 2022, Angelo has published MLS betting previews on various websites, including on Major League Soccer's official betting page for a short while. Through the power of social media, Angelo has been invited to talk soccer betting on national TV & radio on Sports Grid. In Angelo’s free time, he can be found walking his dog and lounging at home watching any game that's on while enjoying his second favourite thing after sports: food! 
Email: [email protected]
Nationality: Canadian
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Experience: 15 years
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