Chivas Guadalajara vs. Cruz Azul Prediction: Liga MX Heavyweights Set for Quarterfinal Battle

• Chivas enters the playoffs on a roll, winning seven of their previous eight contests 

• Cruz Azul finished third overall in the 2025 Apertura table, acquiring 35 points 

Wednesday evening, the first leg of this quarterfinal tilt will take place at Estadio Akron, as Chivas Guadalajara welcomes Cruz Azul. During the regular season, La Máquina obtained a 2-1 victory in August, defeating its adversary for the fourth consecutive time. 

Here, we will break down the betting odds and share our favourite picks for Chivas Guadalajara vs. Cruz Azul.

Chivas Guadalajara vs. Cruz Azul Betting Odds for Wednesday, November 26

The alternate Asian Handicap at +132 has placed the hosts to win within regulation time, while the visitors to win or draw is listed at -175.

Chivas Guadalajara vs. Cruz Azul Odds

The odds for Chivas Guadalajara vs. Cruz Azul can be found in the odds table below, courtesy of BetRivers sportsbook. Sign up for a BetRivers account and claim Up To $500 In Bonus Bets.

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Chivas Guadalajara vs. Cruz Azul Betting Prediction

Chivas Guadalajara Preview

Kicking off the 2025 Apertura, the campaign looked bleak for Gabriel Milito and his troops, flirting near the bottom of the table. Since September, the Rebaño Sagrado have been among the league's hottest sides, propelling themselves into a quarterfinal spot. It’s been a distant time period since Chivas last took the pitch. Their most recent contest was played on November 8, with a 4-2 victory over C.F. Monterrey. 

In a three-way tie to declare this season's Golden Boot winner, Chivas employee Armando González was one of the trio to cap off the Apertura with 12 tallies. The 22-year-old striker appeared out of nowhere to finish as one of Liga MX’s top scorers as he sizzled down the final stretch. In Chivas’ final eight regular-season tilts, González was able to find the back of the net on a goal per game average. This was the first instance since 2019 that a member in a striped goats kit successfully won the Golden Boot award.

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Cruz Azul Preview

Nicolás Larcamón’s men were a steady ship throughout the 2025 Apertura, which saw them finish only two points back for first overall in a tight battle in the standings. Los Cementeros' most recent fixture before the international window saw them suffer a 3-2 setback against Pumas, halting Cruz Azul’s unbeaten run at five. 

The dynamic duo up front, consisting of Ángel Sepúlveda and Gabriel Fernández, will most likely drive the attack on Wednesday. The pair both finished as co-leaders on the team in the goals department during the regular season, cataloging seven goals each. The pressure will once again be on this club as a whole, which has underperformed in prior years. As one of the tycoons of Liga MX, Cruz Azul has won the league title only once since 1997.

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Chivas Guadalajara vs. Cruz Azul - My Pick

Chivas Guadalajara vs. Cruz Azul pick: Cruz Azul +0.5 (-175) at BetRivers

Despite colliding against a solid in-form side on the road, we are still confident that the long layoff has cooled things down for Chivas. Cruz Azul won’t be phased at all, taking their talents to Estadio Akron, where the previous 16 trips have seen Los Cementeros finish only behind on the scoreboard in four outings.

Cruz Azul during the regular season was a difficult opponent, going into the loss column just once in eight away trips while allowing only nine goals. We sense the visitors will try to make this first leg as ugly as possible, limiting Chivas’ attacking abilities to give themselves the vital advantage for the second leg.

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How to Watch Chivas Guadalajara vs. Cruz Azul

• When: November 26, time TBD 

• Where: Estadio Akron 

• TV: Univision Networks (Univision, UniMás, TUDN), Peacock, DirecTV Stream, ViX