Club Tijuana vs. Toluca Prediction: Red Devils Determined to Stay at the Summit

• Club Tijuana are close to clinching a postseason berth, tallying 20 points through 13 rounds 

• Toluca are white hot, winners of eighth straight across all competitions 

Wednesday evening Club Tijuana will welcome the defending Liga MX champions, Toluca at Estadio Caliente. The most recent clash between the two saw the Red Devils double up on their opponent, winning 4-2 during the 2025 Clausura term. 

Here, we will break down the betting odds and share our favourite picks for Club Tijuana vs. Toluca.

Club Tijuana vs. Toluca Betting Odds for Wednesday, October 22

The books have designated the visitors as the likeliest side to win in the moneyline 3-way market. Toluca is listed at -106 while Tijuana is priced at +225. If both teams are level after 90 minutes the draw is inked in at +285.

Club Tijuana vs. Toluca Odds

The odds for Club Tijuana vs. Toluca can be found in the odds table below, courtesy of BetRivers sportsbook. Sign up for a BetRivers account and claim Up To $500 In Bonus Bets.

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Club Tijuana vs. Toluca Odds Betting Prediction

Club Tijuana Preview

It’s been home sweet home for Sebastián Abreu’s troops, as the club currently retains the third strongest home record in Liga MX. Looking to get a boost from its rabid fans, Club Tijuana will try to pin down a spot in the top six of the table to avoid participation in the play-in matches. Los Xolos’ previous five contests have seen them collect two victories. 

In his sophomore season in Liga MX, Frank Boya for the time being is this season's top goal getter with six. The Cameroonian midfielder is a threat controlling the middle of the pitch as he is creating 2.06 shots per 90. On the verge of stardom, talented attacking forward Gilberto Mora is another threat on this club going forward towards the goal. The 17-year-old already is attracting the eyes of European giants due to his fantastic play with Tijuana and representing El Tri, winning the 2025 CONCACAF Gold Cup, making him the youngest winner to hoist an international trophy.

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Toluca Preview

Duplicating the previous campaigns performance, Antonio Mohamed has his men primed for another deep playoff run. The defending league champions currently retain their position at the top of the table, amassing 31 points through 13 outings. After the weekend's fixtures wrapped up, Toluca possessed a three point edge over Cruz Azul, any slip ups from now till the conclusion of the 2025 Apertura could cost them home field advantage throughout the playoffs. 

As a whole this team is lighting up the scoreboard with its abundance of attacking options. Toluca is blowing past its counterparts, averaging three goals per match, with Club América the next best team averaging two goals less. The Red Devils are a team who aren’t dependent on one player to drive the offence, with 13 different members hitting the back of the net.

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Club Tijuana vs. Toluca - My Pick

Club Tijuana vs. Toluca pick: Toluca moneyline 3-way (-106) at BetRivers

The hosts are a respectable team who play their best brand of soccer at home, but we feel Toluca are too much of a juggernaut. The Red Devils are skilled at every position, and it’s no surprise they are in talks to repeat as champions again. Within the goal contribution category ( goals + assists), Toluca outweighs its competitors with five players in the top 25, including Paulinho and Alexis Vega who co-lead Liga MX with 12 a piece. The current golden boot leader, Paulinho is on a tear, registering eight goals in his previous five. We sense Toluca should outclass their adversary on Wednesday, cataloging a fourth straight win over Tijuana.

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How to Watch Club Tijuana vs. Toluca

• When: October 22, 11 p.m. ET

• Where: Estadio Caliente

• TV: Univision Networks (Univision, UniMás, TUDN), Fox Sports (FS1, FS2, Fox Deportes), ViX