Pumas UNAM vs. Santos Laguna Prediction: Gold and Blue Aim to Preserve Perfect Record

• Pumas currently occupy seventh place in the league table after three contests 

• Santos Laguna has only obtained one point to kick off the 2026 Clausura 

On Friday evening, Santos Laguna travels to Estadio Olímpico Universitario to face Pumas UNAM. The most recent encounter saw the Verdiblancos pick apart Pumas, winning 3-0 on their home ground during the 2025 Apertura regular season. 

Here, we will break down the betting odds and share our favourite picks for Pumas UNAM vs. Santos Laguna.

Pumas UNAM vs. Santos Laguna Betting Odds for Friday, January 30

The Asian spread market has the home side priced to win by more than a goal at -103, while the visitors who are +1 on the spread are listed at -121.  

Pumas UNAM vs. Santos Laguna Odds

The odds for Pumas UNAM vs. Santos Laguna in this article are taken from the bet365 sportsbook. Sign up for a bet365 account today with our promo code WSN365 and get $200 in bonus bets.

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Pumas UNAM vs. Santos Laguna Betting Prediction

Pumas UNAM Preview

Leading his boyhood club to a promising start, Efraín Juárez has his troops playing solid soccer after three matches. Before the pause in the Liga MX calendar, Pumas had to muster out a scrappy performance finishing level against Club León. The 29-year-old Brazilian, Juninho, opened his Liga MX account, scoring in the 75th minute to provide the all-important result for his new employers. 

One of the key reasons Pumas are off to an unbeaten start in the competition is their ability to keep their adversaries off the scoreboard. Starting between the sticks, the ex-Real Madrid star Keylor Navas has looked like a brick wall in his second season in a Pumas kit. The Costa Rica international is posting an 88.2 save percentage while securing one clean sheet after three appearances in goal. The center-back pairing of Pablo Bennevendo and Nathan Silva has come up clutch so far, with timely defensive recoveries and precise tackling.

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Santos Laguna Preview

Bench boss Francisco and his men are seeking to find themselves in the win column after Friday evening. It’s been a turbulent start for Santos Laguna as they are only one spot ahead of the basement in the Clausura standings. Before the break, the Guerreros managed to split the points with their opponent, drawing Juárez in a four-goal thriller at Estadio Corona. 

The opening three matches could potentially be the start of a breakout year for a new emerging star on the squad, Fran Villalba. The attacking winger is enjoying a promising start, tallying a goal contribution in each of his three opening Clausura starts. The strong-suited playmaker joined Santos Laguna in July 2024. Friday evening will be his 50th appearance across all competitions; his 49 previous outings have seen him collect four goals and five assists.

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Pumas UNAM vs. Santos Laguna - My Pick

• Pumas UNAM vs. Santos Laguna pick: Pumas UNAM Asian spread -1 (-103) at bet365

We have a hunch Friday’s tilt could see the hosts get the offensive explosion on the scoresheet they are desperately seeking. Pumas has an array of attacking options that have enough to get on the scoresheet on more than one occasion. The previous two meetings at the Estadio Olímpico Universitario saw Pumas blank their challenger while winning by wide margins.

Santos Laguna has shown so far how vulnerable their back-line play is, as they have conceded eight goals, second most to Mazatlán’s nine. Pumas should be able to catch Santos Laguna in a difficult situational spot, exposing the visitors' glaring weakness when they don’t possess the ball at their feet.

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How to Watch Pumas UNAM vs. Santos Laguna

• When: January 30, 10 pm ET 

• Where: Estadio Olímpico Universitario

• TV: Univision Networks (Univision, UniMás, TUDN), DirecTV Stream, ViX, Fubo, CBS Sports