Best MLB Prop Bets Today: Target These Player Props on Wednesday

I have selected five MLB player props that hold significant value on Wednesday. Two of these wagers are in the Cardinals vs Braves matchup. 

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Best MLB Prop Bets Today: Cardinals vs. Braves (12:15 PM, EST)

Miles Mikolas Under 3.5 Strikeouts (-146) at FanDuel Sportsbook

Miles Mikolas has been brutal in 2025 as he is 0-2 with a 7.64 ERA. He has allowed 15 earned runs in 17.2 innings, which isn’t a recipe for success. 

We are starting to see the downfall of Mikolas. Age is becoming a factor in his pitching, and it hasn’t been pretty. 

The Braves are hitting .232 as a team this season, which is in the middle of the pack, but we could see a breakout game from their offense. 

Mikolas allowed eight earned runs against Boston a couple of weeks ago, and we see a similar result in this one. If he doesn’t go deep into the game, he will struggle to find strikeouts.

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Lars Nootbaar Over 1.5 Total Bases (+125) at FanDuel Sportsbook

Lars Nootbaar has been one of the Cardinals' best offensive players this season. He has a solid matchup against Bryce Elder, who will pitch for the Braves. 

Nootbaar is hitting .241 with four home runs and three doubles in 2024. He homered in yesterday’s game between these teams, as he is seeing the ball very well right now. 

The Cardinals have been relying on Nootbaar over the past few seasons, and they trust him a ton. He shoul have another great game against Atlanta, especially with Elder on the mound.

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Best MLB Prop Bets Today: Reds vs. Marlins (1:10 PM, EST)

Sandy Alcantara Over 4.5 Strikeouts (-142) at FanDuel Sportsbook

Sandy Alcantara gets the ball for the Marlins against the Reds, and he should be better following his last start. In that game, he went two innings, allowing six runs on four hits.

Alcantara is one of the best pitchers in the league when he’s on, and this is a great bounce-back spot for him on Wednesday. The Reds are hitting .243 on the season, which ranks 13th in the league. 

Look for Alcantara to get ahead in the count and rack up the strikeouts in this game. His pitch ability is incredible, and we think he punches out at least five batters.

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Best MLB Prop Bets Today: Brewers vs. Giants (9:45 PM, EST)

Logan Webb Over 5.5 Strikeouts (-134) at FanDuel Sportsbook

Logan Webb has been a strikeout machine in 2025, and over bettors have been very happy with his performance so far. He is 2-1 with a 2.40 ERA and has fanned 38 batters in 30 innings. 

In his last start against the Angels, Webb struck out 12 batters in six innings while allowing only one run. He also has a 10-strikeout game against Cincinnati.

Webb has been getting the majority of his outs from strikeouts, and I expect that to continue against Milwaukee.

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Best MLB Prop Bets Today: Rangers vs. Athletics (10:05 PM, EST)

JP Sears Over 4.5 Outs Recorded (-108) at FanDuel Sportsbook

JP Sears squares off against the Rangers, who are hitting .220 as a team this season. The Athletics have been one of the worst teams in the league for batting average. 

Sears is 2-2 with a 3.13 ERA in 23 innings. In his last start, he went six innings allowing no runs on three hits.

Sears props can be a great way to make money on A’s games, with them having no bullpen. He always has a longer leash to stay in the game, and I think Sears clears this number with ease against a bad Texas offense.

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