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Best Bills vs. Patriots Prop Bets: AFC East Rivals Face Off With the Division on the Line

Published: December 13, 2025, 09:00 AM ET
4 min read
  • Stefon Diggs had 146 receiving yards against Buffalo earlier this season

  • The Bills' run defense is allowing the fourth-highest YPC average in the NFL

  • Dalton Kincaid has 108 yards against the Pats in Week 5 against the Pats

Week 15’s slate contains from incredible matchups, but none better than the Buffalo Bills visiting the New England Patriots. Buffalo enters desperate for a win to remain in the AFC East race, while the Pats will be looking to send a message to the doubters with an overwhelming win. That means some incredible prop bets are on the board, giving us some great options to get in on the action.

Best Bills vs. Patriots Prop Bets

Below, we will share our three favorite prop bets for this cross-country AFC battle.

All odds are courtesy of Caesars Sportsbook, one of the best prop betting sites. Sign up with our Caesars promo code WSN20X and claim: Bet $1, Double Your Winnings on Next 20 Bets. Find more details in our Caesars Sportsbook review.

Best Bills vs. Patriots Prop BetsOddsDouble Your Winnings at Caesars
Stefon Diggs Over 48.5 Receiving Yards-114CLAIM HERE
TreVeyon Henderson 60+ Rush Yards+160CLAIM HERE
Dalton Kincaid Over 41.5 Receiving Yards-113CLAIM HERE

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Bills vs. Patriots 2025 12 14

Stefon Diggs Over 48.5 Receiving Yards (-114) at Caesars Sportsbook

We are more than happy to back the former Bills receiver to dominate against his old team. One reason is that we already saw it earlier this season, when Diggs caught 10 passes for 146 yards against his former team. The team’s game plan helped, but there is no question that the veteran receiver is motivated to show the Bills what they are missing.

Diggs has only seen five catches over the last two weeks, despite the New England offense producing a combined 59 points. It was a sharp drop from the previous two seasons, but that will change tonight. With Diggs still showing talent and extra-motivated to put up big numbers, look for Drake Maye to target him early and often on Sunday.

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TreVeyon Henderson 60+ Rush Yards (+160) at Caesars Sportsbook

While his yardage total doesn’t stand out, there is no question about TreVeyon’s status as an electric young running back. He’s averaging 4.8 YPC on the season and has surpassed this total in four consecutive games. The Pats have figured out how best to use the 23-year-old, and it's helped give their already talented offense a significant boost.

Another reason we are backing Henderson is the Buffalo run defense. They allow the fifth-most rushing yards per game (135) and the fourth-highest YPC average (5.1). While they were better last week against the Bengals, Cincinnati’s pass game was working so well that they only attempted 19 rushes.

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Dalton Kincaid Over 41.5 Receiving Yards (-113) at Caesars Sportsbook

Anyone who plays fantasy football knows that Dalton Kincaid is a classic boom-or-bust tight end option. His usage in the offense varies widely, even though the team’s underwhelming receiving corps continues to struggle. The 26-year-old also missed some time on the IR, which he returned from last week. He delivered four catches for 41 yards and a touchdown in his return, but we think he tops that effort this week.

One big reason we love this bet is the tight end’s performance against this team earlier this season. He had six catches for 108 yards, exploiting one of the Pats’ few weaknesses. Considering the Bills are fighting to defend their AFC East title, we expect a massive effort from the offense, which should lead to plenty of action for Kincaid.

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Michael Savio

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Michael is an avid sports fan and a veteran bettor from Milwaukee. He learned the trade from his grandfather in Las Vegas as a kid and has turned that into a successful career. He cheers for all Wisconsin pro teams along with his Alma Mater Arizona State. He specializes in baseball betting, but has experience in football, basketball, and hockey as well. When he isn’t pouring over stats, he’s spending time with his two young children.
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