NFL Preseason Week 3 Picks and Predictions: The Final Rehearsal Before the Regular Season

• The Patriots, Ravens, Browns, Broncos, Chargers, Giants, Buccaneers, and Rams are 2-0

• Three games have ended in a draw so far 

• Road underdogs of +2.5 or less have gone 75-38 over the last 10 years of preseason football 

The third and final week of the NFL preseason has descended, meaning that the NFL world is just a couple of weeks from returning to regularly scheduled programming.

Before the Philadelphia Eagles and Dallas Cowboys can kick-off the new season on Sept. 7, the final week of preseason action must commence. Most star players will be held out to preserve their health, while young players and others competing to make the 53-man roster will get one final chance to make a name for themselves.

Which players will rise above the competition, and which teams should you be taking a close look at? Here are my best NFL preseason Week 3 picks and bets.

NFL Preseason Week 3 Picks

• Eagles vs. Jets under 37.5 points (-110)

• Broncos -3.5 (-115) vs. Saints

• Bills +1 (-110) vs. Buccaneers

• And more…

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NFL Preseason Week 3 Predictions and Odds

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Steelers vs. Panthers - Aug. 21, 7:00 p.m. ET

Spread: Steelers -2.5 (-110), Panthers +2.5 (-110)

Moneyline: Steelers -140, Panthers +120

Total: Over/under 36.5 (-110/-110)

The Steelers’ backup quarterbacks came back down to earth last week, combining for a touchdown and three interceptions in a 17-14 loss to the Buccaneers. The Panthers, meanwhile, have only scored 13 points in two preseason games and have been totally inefficient on offense, even though they did an okay job on defense against the Texans. Backups or starters, the Steelers are a much better team.

• Steelers vs. Panthers pick: Steelers -2.5 (-110) at bet365

Patriots vs. Giants - Aug. 21, 8:00 p.m. ET

Spread: Patriots +3.5 (-110), Giants -3.5 (-110)

Moneyline: Patriots +150, Giants -180

Total: Over/under 37.5 (-110/-110)

Josh Dobbs and Efton Chism III led the Patriots to a 20-12 win over the Vikings last week despite Minnesota finding success moving the ball through the air. The Giants are averaging 32.5 points per game during the preseason but were gashed on the ground, even though they only surrendered 12 points to the Jets. I’d watch for this game to potentially fly over its projected total.

• Patriots vs. Giants pick: Over 37.5 points (-110) at bet365

Eagles vs. Jets - Aug. 22, 7:30 p.m. ET

Spread: Eagles +1 (-110), Jets -1 (-110)

Moneyline: Eagles +100, Jets -120

Total: Over/under 37.5 (-110/-110)

Tanner McKee’s exclusion from last week’s game meant that the Eagles were outmatched against the Browns – assuming he’s out again, this Eagles offense has very little potency. The Jets, meanwhile, also do not have an impressive running or passing game, even by preseason standards. This feels more like an under game.

• Eagles vs. Jets pick: Under 37.5 points (-110) at bet365

Falcons vs. Cowboys - Aug. 22, 8:00 p.m. ET

Spread: Falcons +3.5 (-105), Cowboys -3.5 (-115)

Moneyline: Falcons +155, Cowboys -185

Total: Over/under 36.5 (-110/-110)

The Falcons are still looking for their first win of the preseason and will turn to Ben DiNucci after releasing Emory Jones. They’ll face a Cowboys team that also hasn’t tasted victory and only managed 51 yards on 20 carries last week. While it’s tough to love anything about either team, getting the Falcons on a 3.5-point line has value, given the Cowboys haven’t impressed.

• Falcons vs. Cowboys pick: Falcons +3.5 (-105) at bet365

Vikings vs. Titans - Aug. 22, 8:00 p.m. ET

Spread: Vikings +1 (-110), Titans -1 (-110)

Moneyline: Vikings -105, Titans -115

Total: Over/under 37.5 (-110/-110)

Without J.J. McCarthy and Sam Howell getting significant, if any, reps, the Vikings’ QB room will struggle to produce, and their running game has been terrible. The Titans aren’t loaded with talent themselves, but they have some talented youngsters who could see the field. This is the only time I’d say this, but I like the Titans more than the Vikings.

• Vikings vs. Titans pick: Titans ML (-115) at bet365

Bears vs. Chiefs - Aug. 22, 8:20 p.m. ET

Spread: Bears +3 (-105), Chiefs -3 (-115)

Moneyline: Bears +145, Chiefs -170

Total: Over/under 38.5 (-110/-110)

Ben Johnson wasn’t holding back on either side last week as the Bears thumped the Bills 38-0. They’ll take on a Chiefs team that is 0-2 in the preseason, but one that still has talent to be competitive. That said, the Bears are more focused on winning this game than the Chiefs are, and they have talented backups.

• Bears vs. Chiefs pick: Bears ML (+145) at bet365

Ravens vs. Commanders - Aug. 23, 12:00 p.m. ET

Spread: Ravens -2.5 (-110), Commanders +2.5 (-110)

Moneyline: Ravens -140, Commanders +120

Total: Over/under 35.5 (-110/-110)

The Ravens were on a 24-game preseason win streak until 2023, and they’re on their way to starting a new streak now that they’re 2-0 in 2025. The Commanders are 0-2 and haven’t impressed with their depth in the QB or CB rooms, which is an issue against a superior Ravens team. Look for the favorites to run their way to victory,

• Ravens vs. Commanders pick: Ravens ML (-140) at bet365

Broncos vs. Saints - Aug. 23, 1:00 p.m. ET

Spread: Broncos -3.5 (-115), Saints +3.5 (-105)

Moneyline: Broncos -185, Saints +155

Total: Over/under 37.5 (-110/-110)

The Broncos dominated both of their preseason opponents offensively and defensively, winning by a combined score of 57-16. The Saints, as I’ve said for two weeks running, have the worst quarterback room in professional football and needed an Octopus with 0:21 remaining to grab a 17-17 tie against the Jaguars last week. Call me boring, but I plan on fading the Saints for the third week running.

• Broncos vs. Saints pick: Broncos -3.5 (-115) at bet365

Texans vs. Lions - Aug. 23, 1:00 p.m. ET

Spread: Texans +1.5 (-110), Lions -1.5 (-110)

Moneyline: Texans +100, Lions -120

Total: Over/under 35.5 (-110/-110)

It’s silly to count on the Texans’ offense to do anything productive without C.J. Stroud on the field. The Lions also scored an average of 11.3 points per game across three outings, and they’re about to go against a defense-oriented team. This game screams the under.

• Texans vs. Lions pick: Under 35.5 points (-110) at bet365

Colts vs. Bengals - Aug. 23, 1:00 p.m. ET

Spread: Colts -1.5 (-110), Bengals +1.5 (-110)

Moneyline: Colts -130, Bengals +110

Total: Over/under 38.5 (-110/-110)

Prepare for the Riley Leonard show now that Daniel Jones has been announced as the starter over Anthony Richardson. Jake Browning is a great backup QB, but there’s no guarantee that he gets significant playing time in this matchup. The Bengals’ defense couldn’t stop a cold against the Commanders, but the under looks pretty enticing here.

• Colts vs. Bengals pick: Under 38.5 points (-110) at bet365

Rams vs. Browns - Aug. 23, 1:00 p.m. ET

Spread: Rams +5 (-110), Browns -5 (-110)

Moneyline: Rams +180, Browns -220

Total: Over/under 37.5 (-110/-110)

Stetson Bennett played a nice game against the Chargers last week, even though he hilariously got trucked by a defensive tackle who intercepted one of his passes. The Browns, meanwhile, are full of uncertainty and appear to have internal issues based on Dillon Gabriel’s comments. The Rams might be willing to rest more key players, but they’re a much, much, much better run franchise.

• Rams vs. Browns pick: Rams +5 (-110) at bet365

Seahawks vs. Packers - Aug. 23, 4:00 p.m. ET

Spread: Seahawks -1 (-110), Packers +1 (-110)

Moneyline: Seahawks -115, Packers -105

Total: Over/under 38.5 (-110/-110)

The over is 2-0 in Seahawks preseason games, and they just ran for 268 yards and two TDs on the Chiefs. They’ll meet the Packers, who won outright as a six-point underdog against the Colts last week, also thanks to a strong day on the ground. This has the makings of a tight battle, but I’d lean toward the Seahawks.

• Seahawks vs. Packers pick: Seahawks ML (-115) at bet365

Jaguars vs. Dolphins - Aug. 23, 7:00 p.m. ET

Spread: Jaguars +3.5 (-110), Dolphins -3.5 (-110)

Moneyline: Jaguars +150, Dolphins -180

Total: Over/under 38.5 (-110/-110)

Jacksonville’s offense had a nice day against the Steelers, but the non-Trevor Lawrence crew was tame against the Saints. The Dolphins scored 24 points in each of their first two preseason games and seem to be in a rhythm with Ollie Gordon II dominating the ground and the Zach Wilson-Quinn Ewers QB combo. I’d recommend taking the Dolphins in this one.

• Jaguars vs. Dolphins pick: Dolphins -3.5 (-110) at bet365

Bills vs. Buccaneers - Aug. 23, 7:30 p.m. ET

Spread: Bills +1 (-110), Buccaneers -1 (-110)

Moneyline: Bills -105, Buccaneers -115

Total: Over/under 37.5 (-110/-110)

The Bills were shut out against the Bears and allowed 36 points per game during the preseason. The Bucs have tons of preseason weapons, although it appears as if Sean Tucker, Emeka Egbuka, and several others are being preserved for the regular season. This could be a sneaky place to take the Bills to bounce back, as they still have competent veterans on their squad.

• Bills vs. Buccaneers pick: Bills +1 (-110) at bet365

Chargers vs. 49ers - Aug. 23, 8:30 p.m. ET

Spread: Chargers +3 (-110), 49ers -3 (-110)

Moneyline: Chargers +140, 49ers -165

Total: Over/under 37.5 (-110/-110)

The Chargers are one of two teams to play three preseason contests, and they scored at least 22 points in all of them. The Niners, meanwhile, are incredibly injured and won’t have Mac Jones available to lead the reserves. This is a nice opportunity to grab the Chargers despite their scoring output dropping in three straight games.

• Chargers vs. 49ers pick: Chargers +3 (-110) at bet365

Raiders vs. Cardinals - Aug. 23, 10:00 p.m. ET

Spread: Raiders +1.5 (-110), Cardinals -1.5 (-110)

Moneyline: Raiders +105, Cardinals -125

Total: Over/under 37.5 (-110/-110)

Pete Carroll’s reimagination of the Raiders is starting to take hold, although they’re yet to taste victory in the preseason. The Cardinals, meanwhile, only gained 135 yards of total offense against the Broncos after they opened their year with a win against the Chiefs. I like the look of the Raiders in this contest.

• Raiders vs. Cardinals pick: Raiders ML (+105) at bet365

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