Best MLB Home Run Props Today: Fernando Tatis Jr. to Thrive in the High Altitude of Denver

Today’s slate of games brings us some fantastic home run bets. We have several back-end starters on the mound, giving us plenty of bats to choose from. We are locking in three of those today, which we will share below.

The odds we use for our home run bets are taken from Caesars Sportsbook. Create a Caesars account using our promo code WSNDYW to claim a “Bet $1, Get Ten 100% Profit Boost Tokens” offer.

Home Run Picks for Friday, May 9

Rhys Hoskins 1+ Home Runs (+280) at Caesars Sportsbook

Rays’ starter Zack Littell has vastly improved over the last few weeks, but has still been vulnerable to the deep ball. He has allowed the second-most in baseball, and gave up two in his last time out.

The Brewers have lacked power in 2025, but Rhys Hoskins will have a great chance to change that tonight. The slugger is starting to heat up with a three-game hitting streak, and he has had success against Littell. This game may not have a ton of runs, but Hoskins will do some damage tonight.

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Fernando Tatis Jr. 1+ Home Runs (+200) at Caesars Sportsbook

Fernando Tatis Jr. is our favorite home run bet of the day. We know he has the power to go deep at any moment, and he’ll be playing at hitter-friendly Coors Field. While the 26-year-old has done his best work at home this season, he will thrive in the high altitude of Denver tonight.

Tatis will face Antonio Senzatela on the mound tonight. The veteran has been awful, posting a 5.50 ERA and a brutal 1.86 WHIP. These numbers are similar to those from 2024, and his 7.63 ERA at Coors Field shows that being at home isn’t helping. Look for him to post another brutal outing, including one home run from Tatis.

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Shohei Ohtani 1+ Home Runs (+230) at Caesars Sportsbook

This price isn’t great, but betting on Ohtani to go deep in May has been easy money. He has been hammering opposing pitchers and kicked off the month by hitting three home runs over his first five games. The three-time MLB MVP seems to have found his groove, and we are riding his hot streak tonight.

Ohtani will face D-backs starter Eduardo Rodriguez (1-3, 5.92 ERA, 1.47 WHIP) on the mound tonight. The veteran lefty has been struggling badly over his last few starts, with his last quality start coming back on April 11. He has given up five deep balls over his last three games, and Ohtani will help raise that total in this one.

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