Vancouver Whitecaps FC vs. St. Louis City SC Prediction: Caps Work to Recover After Muller's Festivity Falters

• Vancouver is still in the race to claim top spot in the Western Conference, currently sitting six points back 

• St. Louis City SC's 2025 campaign has been in a tailspin since it opened, obtaining only five wins this year

Saturday evening, the Vancouver Whitecaps welcome St. Louis City SC to BC Place in round 28 of the 2025 MLS campaign. These two have already squared off this term, which materialized into a scoreless draw back in late April. 

Here, we will break down the betting odds and share our favorite picks for Vancouver Whitecaps FC vs. St. Louis City SC. 

Vancouver Whitecaps FC vs. St. Louis City SC Betting Odds for Saturday, August 23

The hosts in Saturday’s tilt are pegged as the heavy favorite to win. The moneyline 3-way market is paying -182 for Vancouver to win, while for St. Louis, they’re listed at +400. If both sides are level after the full-time whistle, the draw is priced at +375. 

Vancouver Whitecaps FC vs. St. Louis City SC Odds 

The following odds are taken from bet365 sportsbook. Use our promo code WSN365 at bet365 to claim your bonus: Bet $5, Get $200 in Bonus Bets Win or Lose.

Vancouver Whitecaps FC vs. St. Louis City SC Betting Prediction 

Vancouver Whitecaps FC Preview 

Thomas Müller made his anticipated debut on Sunday, which saw Vancouver fail to hold onto its one-goal lead, conceding in the late stages to settle on a 1-1 draw against the Houston Dynamo. The German soccer legend showed flashes of his brilliant class in his 30-minute outing. The 36-year-old looked to have opened his MLS account in his first appearance, but his tally was waved off for offside. 

This season, American, internationally capped forward Brian White is leading the goal getter for Vancouver this season. Making a name for himself in the last few years, his play this year has put him into the conversation about joining the USMNT for the World Cup next summer. The 29-year-old possesses a lethal boot, registering 13 tallies off 26 shots on target.

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St. Louis City SC Preview 

David Critchley has had his work cut out, taking over the reins on the touch line in late May, trying to steer the sinking ship. He has prevailed to be a worthy candidate to remove the interim tag from his coaching title. Since taking over St.Louis, the team has amassed 10 points in 11 MLS tilts, with room for improvement. 

Joao Klauss has railed effectively from the 2024 form that only saw him hit the back of the net in five instances throughout MLS. 25 games into this campaign, the striker has obtained eight goals, two shy of his career high set in 2023.

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Vancouver Whitecaps FC vs. St. Louis City SC - My Pick

Vancouver Whitecaps FC vs. St. Louis City SC pick: Vancouver Whitecaps FC ML 3-way (-182) at bet365

Saturday’s encounter should see the hosts prevail, getting back on track after dropping two points in their match against Houston. The situation is a tad different for Vancouver this instance, as they will have six days off between game action unlike the three days rest they had heading into Sunday’s fixture with travel involved. It’s going to take time, but Müller in his first league cameo showed what kind of player he can be in MLS if he can develop chemistry with his teammates. St. Louis has been abysmal on the road in 2025, accruing one win in 13 away trips.

The Whitecaps are a force at BC Place, winning seven of their 12 home matches while only surrendering 14 goals. If Vancouver wants to keep pace with expansion side San Diego FC for top spot in the west, this is a bout the home side must win.

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How to Watch Vancouver Whitecaps FC vs. St. Louis City SC 

• When: August 23, 9:30 p.m. ET

• Where: BC Place

• TV: Apple TV - MLS Season Pass, Apple TV+