Anytime Touchdown Scorer Predictions in Week 16: Expect Saquon Barkley to Build on His Momentum

• Saquon Barkley rushed for 78 yards in last week’s win against Las Vegas

• The Chicago Bears are listed as the betting favorite to win the NFC North

• The Washington Commanders rank below league average in Run Defense PFF Grade

After a slow start to the year, Saquon Barkley has started to round back into form as the Philadelphia Eagles running back rushed for 78 yards in last week’s win against Las Vegas. Heading into week 16, expect Barkley to build on his momentum in a NFC East divisional matchup against the Washington Commanders as he faces off against a defense who struggles to plug the running lanes in the trenches.

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Saquon Barkley Anytime Touchdown Scorer (-120) at BetMGM Sportsbook

After winning the Offensive Player of the Year award last year, Saquon Barkley has struggled to carry over his success into this season as the Philadelphia Eagles running back is averaging fewer Yards per Carry than he did in 2024-25. A stunning development when factoring in the protection he receives from his offensive line as the Eagles front five ranks top-10 in Run Block Line Yards.

Fortunately for Barkley, he will have a great opportunity to round back into competitive form on Saturday as he faces off against the Washington Commanders who rank below league average in Run Defense PFF Grade. With the Commanders struggling to create pressure in the interior, Barkley will be able to consistently break through the trenches and generate a high volume of explosive runs.

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Romeo Doubs Anytime Touchdown Scorer (+170) at BetMGM Sportsbook

With three games remaining in the regular season, the Chicago Bears are in full control of their own destiny as they possess a half game lead for first in the NFC North division standings. While their offense has thrived, their defense brings in a high amount of variance in their contest as they currently rank well below league average in Def DVOA and in Pass Rush Win Rate.

The Bears struggles with collapsing the pocket bodes well for Jordan Love as the Green Bay Packers quarterback resides near the top of the board in Quarterback EPA per Play and in Big Time Throw Percentage. When in scoring position, expect Love to continue to look towards Romeo Doubs way as he leads the team in Red Zone Targets while converting over half of his Receptions into touchdowns.

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Javonte Williams Anytime Touchdown Scorer (-165) at BetMGM Sportsbook

Since joining the Dallas Cowboys in the offseason, Javonte Williams has been able to turn his career around as the former Denver Broncos running back ranks above league average in Yards Over Expected per Attempt. With his offensive line consistently opening up holes in the trenches as their top-10 mark in Run Block Set Grade indicates, Williams is able to reach the second level of the defense at a high rate.

Heading into Sunday, expect Williams to continue to find success in the Red Zone as he faces off against a defense who ranks near dead last in Run Defense Win Rate. Especially with CeeDee Lamb and George Pickens pulling defensive attention away from the middle as the width of Williams running lanes will widen which increases his chances of scoring.

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De’Von Achane Anytime Touchdown Scorer (-200) at BetMGM Sportsbook

Even with Miami’s offense struggling as a whole, De’Von Achane has been able to play at a high level as the Dolphins running back is averaging nearly one touchdown per game. In a favorable matchup against Cincinnati, expect Achane to put together a dominant performance as he faces off against a Bengals defense who ranks 32nd in Def EPA. For some more exposure, escalator bet Achane’s touchdown scoring prop by placing smaller wagers on his alternate totals at the best available odds.

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