NFL Win Totals Over/Under Predictions 2025: Bills Favorites to Lead in Regular Season Wins

• The win totals for the Indianapolis Colts (7-1) and New England Patriots (6-2) saw the largest positive adjustment, with both teams now sitting around an implied 10.5 to 11.5 wins.

• The Kansas City Chiefs (5-3) and Buffalo Bills (5-2) maintained their high, double-digit win totals (around 10.5 to 11.5).

• The combined win total of the AFC North plummeted as the Pittsburgh Steelers (4-3) and Baltimore Ravens (2-5) suffered continued setbacks.

NFL Win Totals Odds

The odds below are courtesy of FanDuel. Sign up for FanDuel account and claim your welcome offer: Bet $5, Get $150 in Bonus Bets if Your Bet Wins.

FanDuel is among the best NFL betting sites for betting on win totals and other NFL futures markets.

Who Will Lead the 2025 NFL Season in Wins - Buffalo Bills

The Buffalo Bills are consistently the strongest betting candidate to lead the NFL in regular season wins, reflected by their win total line being set as high as 12.5 (with the Over frequently favored). This high projection is justified by the proven production of their offense, which has consistently ranked top-five in efficiency under quarterback Josh Allen, who is coming off an MVP season.

Furthermore, the Bills benefit from one of the league's easier strength of schedules, particularly with the relative weakness of their AFC East rivals (Patriots, Jets, Dolphins) and the advantage of playing key AFC Championship contenders like the Chiefs, Ravens, and Eagles at home in Buffalo, ensuring they have the clearest path to the top regular-season record.

Win a $5 Wager at FanDuel, Get $150 in Bonus Bets

How to Bet on NFL Win Totals

There are a couple of ways in which you can bet on NFL win totals. 

The first are the markets seen above—the over/under amount on a specific set line. Alternatively, some sportsbooks will allow multiple options for over/under lines. For example, the Patriots may have a set line of 8.5, but there would be an option to bet on “Over 10.5” for even better odds value-wise if you believe in them to that extent. 

To add, you can, of course, wager on each NFL game to complement your futures bets. 

How to Read NFL Win Total Odds

Here’s how to read NFL odds. For this exercise, I’ll examine it through the lens of winning $100 or wagering $100. 

• With “+” odds, you’ll win the amount displayed as the odds with a successful $100 bet. For example, the Patriots are +115. You’d win $115 with a winning $100 bet. 

• With ‘-” odds, you must wager the amount associated with the odds to win $100. So, if the Patriots were -115, you’d need to wager $115 to win $100. 

Where to Bet on NFL Win Total Odds

FanDuel Sportsbook: FanDuel provides players with the following welcome offer: Bet $5, Get $150 in Bonus Bets if Your Bet Wins. There are ample ways to bet on NFL win totals, including each team’s set line and alternative lines.

Caesars Sportsbook: In addition to the best odds boosts you’ll find at online sports betting sites, Caesars Sportsbook provides players with a generous welcome offer: Bet $1, Double Your Winnings Next 20 Bets after you use our promo code WSN20X during the registration process. Read our detailed Caesars Sportsbook review and get more info.

BetMGM Sportsbook: As a new player, you eligible to claim their current promo offer: Get Up to $1,500 in Bonus Bets*. Just remember to use our promo code WSNSPORTS during registration. Also, BetMGM offers some free-to-play games to earn bonus bets, and there are a plethora of NFL futures bets, including win totals.

*21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. This promotional offer is not available in DC, MS, NY, NV, ON, or PR.

NFL Win Total Leader History

Below, we’ll go back through 2010 to see which team(s) led the league in wins each season. 

It’s worth noting that, over this time, the regular season switched from 16 games to 17 games. The regular season expanded to 17 games in 2021. 

While we’re not going back over the course of NFL history, here’s a complete breakdown of how the schedule has changed since 1967. 

• 1967-1977: 14 games

• 1978-1981: 16 games

• 1982: Nine games (strike)

• 1983-1986: 16 games

• 1987: 15 games (strike)

• 1988-1989: 16 games, no bye week

• 1990-1992: 16 games, one bye week

• 1993: 16 games, two bye weeks

• 1994-2000: 16 games, one bye week

• 2001: 16 games, two bye weeks (September 11 attack)

• 2002-2020: 16 games, one bye week

• 2021-Present: 17 games, one bye week