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Ravens vs. Lions Prediction: Is Monday’s Game a Potential Super Bowl Preview?

Updated: September 22, 2025, 05:17 AM ET
7 min read
  • The Ravens have won six of their seven head-to-head games with the Lions.

  • Baltimore lost in Week 1 despite holding a 15-point lead with four minutes left.

  • Jared Goff threw for 334 yards and five touchdowns in Week 2. 

Could NFL fans be about to see a Super Bowl preview on Monday night? It’s not out of the question when the Detroit Lions visit the Baltimore Ravens. Both teams have come frustratingly close to the Super Bowl in recent years, only to come up short. Of course, the Lions and Ravens are just trying to avoid losing their second game of the season, as both sides enter Monday’s game 1-1. That makes this game critical for both sides, as neither team wants to risk falling too far behind in their division early in the season. 

Historically speaking, the Ravens have the edge in this game, as they’ve won six of seven head-to-head games with Detroit, including a 38-6 shellacking when the Lions visited Charm City two years ago.

We weren’t joking when we said this could be a Super Bowl preview. The Ravens currently have the shortest Super Bowl LX odds, while the Lions have the sixth-shortest odds to lift the Lombardi Trophy this season. Fittingly, Lamar Jackson is among the leading favorites to win NFL MVP honors this season, while Detroit’s Jared Goff remains an interesting sleeper pick.

Ravens vs. Lions Odds

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Baltimore Ravens-225-4.5 (-110)Over 53.5 (-110)
Detroit Lions+185+4.5 (-110)Under 53.5 (-110)
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Ravens vs Lions 2025 09 22

Ravens vs Lions: My Pick

A Monday night game in Baltimore is no easy task for the visiting team. That’s particularly true given the way Lamar Jackson and the Ravens have looked early in the season, at least on offense. But a Week 1 loss in Green Bay aside, the Lions are no ordinary visitor. This has been one of the best teams in the NFL over the last few years. The Lions also won every road game they played in 2024, which is why I’m leaning toward Detroit and the points on Monday night.

Granted, the new-look Green Bay defense got the better of the Lions in Week 1. But that game is likely to be more of an aberration than a sign of things to come. Keep in mind that even with a big lead in Week 1, the Baltimore defense wasn’t able to seal the deal against the Bills. That makes it hard to trust them against another high-powered offensive team.

Also, it’s best to take Baltimore’s 41-17 blowout of the Browns last week with a grain of salt. The Browns are likely to be among the worst teams in the NFL this season, so it’s tough to draw too many conclusions about the Ravens from that victory. It’s not that they aren’t capable of beating the Lions at home, but rather the best bet is to take the underdog in a game that could easily go either way.

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Ravens vs. Lions Prediction

Baltimore Ravens Preview

There’s no doubt that Lamar Jackson has an early head start on winning his second MVP. He has six passing touchdowns and one rushing touchdown through two games, while completing just under 69% of his passes with no interceptions. Meanwhile, Derrick Henry looked unstoppable for large stretches in Week 1, giving the Ravens one of the best tandems in football. 

On the other hand, there are lingering concerns about the Baltimore defense after a late-game collapse in Week 1. Even against the Bills, a 15-point lead with four minutes left should be safe. While Jared Goff doesn’t have the mobility of Josh Allen, the Lions have more dynamic skill players than the Bills, which will challenge a Baltimore defense that is already dealing with injuries and depending on rookies to play important roles.

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Detroit Lions Preview

The Lions were undoubtedly punched in the mouth in Week 1. The running game went nowhere, with Goff constantly under pressure, taking four sacks. Nevertheless, Goff was rather efficient in that game, connecting on 31 of his 39 passes. He and the Lions then managed to hit their stride in Week 2. Goff completed 23 of his 28 passes for 334 yards and five touchdowns, showing what the Detroit offense is capable of doing when things are clicking.

As usual, the Detroit defense has some questions, even if that unit only needs to be average for the Lions to win games. Giving up over 20 points to both the Packers and Bears doesn’t exactly bode well heading into a game against Jackson and the Ravens. However, the Lions have a fair amount of talent on that side of the ball. They’ve also been able to avoid giving up big plays, which could be enough to allow the dynamic Detroit offense to go toe to toe with the Ravens on Monday.

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Ravens vs. Lions Injuries

Baltimore Ravens

  • Isaiah Likely (TE)  - Questionable

  • Patrick Ricard (FB) - Questionable

  • Emery Jones Jr. (OL) - Out

  • Kyle Van Noy (LB) - Questionable

  • Marlon Humphrey (CB) - Questionable

Detroit Lions

  • Miles Frazier (OL) - Out

  • Marcus Davenport (DE) - Questionable

  • Trevor Nowaske (LB) - Questionable

Ravens vs. Lions: Best Promos and Sportsbooks

If you look around, most of the top NFL betting sites run special promotions during Monday Night Football games. Whether you’re an existing customer at those sites or looking to create a new account, check out the latest NFL betting promos in the table below.

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How to Watch Ravens vs. Lions

  • When: Monday, September 22, 8:15 PM

  • Where: M&T Bank Stadium, Baltimore, Maryland

  • How to Watch: ABC/ESPN

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Bryan Zarpentine WSN Contributor

Bryan Zarpentine

Sports Betting Analyst

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Bryan Zarpentine is a 2008 graduate of Syracuse University and has been working as a freelance writer and editor since 2010. During that time, he has contributed to countless sites while covering baseball, soccer, the NFL, college football, and college basketball.
Email: bryan.zarpentine@wsn.com
Nationality: American
Education: Bachelor of Arts
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