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Ravens vs. Bills Prediction: A Potential AFC Conference Championship Preview

Published: September 5, 2025, 10:00 AM ET
6 min read
  • The Baltimore Ravens are listed as the betting favorite to win the Super Bowl

  • The Buffalo Bills' quarterback Josh Allen won the MVP award last season

  • Baltimore’s offense ranked top-3 in Off DVOA, EPA, and in Success Rate

Week one provides us with an exciting matchup on Sunday night as the Baltimore Ravens and Buffalo Bills are listed near the top of the oddsboard to win the Super Bowl. With question marks still looming over the Bills on both sides of the field, the Ravens are in a great position to secure the win and make a claim for being the best team in the league.

Baltimore Ravens vs. Buffalo Bills Odds

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Teams Moneyline Spread Total
Baltimore Ravens -115 -1 (-105) 50.5 (-115)
Buffalo Bills -105 +1 (-115) 50.5 (-105)

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Ravens vs Bills 2025 09 07

Baltimore Ravens vs. Buffalo Bills My Pick

After narrowly winning the NFL MVP award, Lamar Jackson looks to carry over his momentum into this season as he faces off against a Bills defense who struggles to collapse the pocket as their front seven ranked 19th in Adjusted Sack Rate. Even after signing Joey Bosa in the offseason, the Bills draw a tough first assignment as the Ravens' offensive line finished near the top of the board in Line Yards.

Buffalo’s tendency to anchor their linebackers in coverage will also open up more rushing lanes for Lamar Jackson to exploit, especially if the Bills front four continues to struggle with generating pressure. This drastically increases the Ravens' chances of moving the ball down the field at a consistent rate, giving them extra opportunities to turn their possessions into points on the board.

On the other side of the field, the Ravens addressed their struggles on defense by selecting Malaki Starks and Mike Green in the NFL Draft. With the second level of their defense expected to round back into dominant form, the Ravens can continue to send pressure through the middle to force Josh Allen into scrambling situations while their secondary holds their own in coverage.

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Baltimore Ravens vs. Buffalo Bills Prediction

Baltimore Ravens Preview

After finishing last year ranked in the top-3 in Off DVOA, EPA, and in Success Rate, the Baltimore Ravens are expected to thrive once again as they bring back a majority of their cast that lead them to their top-ranked marks. Especially with health back on their side as their offensive line struggled to stay on the field for a majority of the season last year.

As for their defense, positive regression looms large as the Ravens were aggressive in their efforts in improving that side of the ball throughout the offseason. Even in a down year, the Ravens defense were still a competitive unit as they ranked 11th in Def Pass DVOA and 4th in Def Rush DVOA. Should they improve on last year’s marks, then the Ravens can make a case for being the most well-rounded team in the league.

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Buffalo Bills Preview

Josh Allen looks to build on his momentum by shouldering a bigger workload after the Bills failed to bolster their offense in the offseason. Especially if starting running back James Cook gets off to a slow start after holding out of practice while negotiating a contract extension, potentially forcing the Bills to be one-dimensional while leaning heavier on the pass.

Buffalo’s defense, meanwhile, still has massive question marks looming over them, primarily in the secondary after their first-round draft pick Maxwell Hairston suffered an injury and went on IR. Their struggles in coverage held them back from being a juggernaut last season as the Bills' defense ranked 25th in Def Pass Success Rate and 19th in Def Pass EPA.

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Baltimore Ravens vs. Buffalo Bills Injuries

Baltimore Ravens

  • Isaiah Likely - Questionable

  • DeAndre Hopkins - Questionable

  • Jaire Alexander - Questionable

Buffalo Bills

  • Khalil Shakir - Questionable

  • Tre’Davious White - Questionable

  • Maxwell Hairston - Out

Ravens vs. Bills: Best Promos and Sportsbooks

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How to Watch Ravens vs. Bills

  • When: September 7, 8:20 pm EST

  • Where: Highmark Stadium, Orchard Park, New York

  • How to Watch: NBC

More NFL Week 1 Stories

NFL Week 1 Odds

Ravens vs. Bills Prop Bets SNF Week 1

Bills vs. Ravens Same Game Parlay SNF Week 1

NFL Week 1 Picks Against the Spread

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Kody Malstrom WSN Contributor

Kody Malstrom

Sports Betting Analyst

Expertise:
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Kody Malstrom is a sports betting journalist with six years of writing experience in the industry. He covers an abundance of sports, including College Football, NFL, College Basketball, NBA, and more. Born and raised in Michigan, Kody is a devoted Detroit Sports fan and spends his Sundays rooting for the Detroit Lions while telling himself this year is the year they win it all. When not staring at betting markets, Kody spends his free time at the beach in the summer or snowboarding in the winter.
Email: [email protected]
Nationality: American
Education: Bachelor of Finance
Favourite Sportsbook: Caesars Sportsbook
Favourite Casino: BetMGM Casino
Experience: 6 years
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