ATP Miami Open Predictions, Betting Odds, Picks
- Kyrgios tie-break fancy
- Musetti can repeat trick
- Sinner makes outright appeal
ATP Miami Picks
Over 0.5 tie-breaks in Nick Kyrgios v Adrian Mannarino at +162 at bet365
Lorenzo Musetti to beat Alexei Popyrin 2-0 at +165 at FanDuel
Dominik Koepfer to beat Mackenzie McDonald at +215 at PointsBet
Soonwoo Kwon to beat Brandon Nakashima at +130 at Caesars Sportsbook
Jannik Sinner to win the Miami Open at +3000 at FanDuel
See what’s the best online sportsbook for payouts before you sign up!
Play Fantasy Sports Here!

Nick Kyrgios vs Adrian Mannarino
With his strong serve and relatively poor return game, Kyrgios is a tie-break regular and I think +162 about there being one in this clash is overpriced.
Mannarino, who has seen a tie-break in four of his last seven matches on outdoor hardcourts, has dealt with some of the game’s biggest servers pretty well in the past. For example, he’s forced a tie-break in five of eight meetings with John Isner, four of seven v Sam Querrey and two of four against Milos Raonic.
These two haven’t met before which should only enhance the chances of serve dominating.
Admittedly Kyrgios played rather well in Indian Wells earlier this month with only one of his four matches featuring a breaker, which probably helps explain the price.
Still, +162 looks worth a go.
Lorenzo Musetti vs Alex Popyrin
It’s been a tough season so far for Popyrin, who is just 2-8 in 2022.
His most recent loss came against Musetti at the Phoenix Challenger last week when he won only four games and didn’t break serve.
That’s hardly a good omen for this match in conditions that should favour the Italian more – Popyrin likes it fairly quick but in Miami, the humidity slows things down, while the Laykold court isn’t the fastest either.
Musetti has now won the pair’s last three meetings, all in straight sets, and that looks the bet here at +165.
Mackenzie McDonald vs Dominik Koepfer
Koepfer was competitive against Andrey Rublev in Indian Wells recently and could land an upset blow here.
Level at 1-1 on the head-to-head, the pair’s last meeting went the way of McDonald, who won 7-6 in the third in Cincinnati in 2020.
McDonald is another who prefers a slick court but while he had that in Cincinnati, that won’t be the case this week and Koepfer could benefit at odds of +215.
The American favorite has been rather disappointing so far in 2022 and comes into this clash with a losing record (7-8). He’s also got a track record of struggling (relatively) against left-handers, holding another losing record in his career as a whole.
I just think Koepfer is too big here and worth chancing.
Soonwoo Kwon vs Brandon Nakashima
Like his compatriot McDonald, Nakashima has been something of a let-down so far this season.
He’s won back-to-back matches only once and that was right at the start of the campaign in Australia.
Usually very much at home on the North American hardcourts, Nakashima has gone 3-5 since returning to the US.
The dogged Kwon can take advantage.
The gritty Korean has been solid if unspectacular so far in 2022. He took a set off Andrey Rublev in Dubai and prior to that pushed Denis Shapovalov all the way at the Australian Open.
On current form, he’s more than capable of living with a low-on-confidence Nakashima and looks worthy of support at +130.
Round Two Upsets
The seeds all get a first-round bye at the Miami Open so which of them could be vulnerable in round two?
Karen Khachanov won just three games against Jenson Brooksby in Indian Wells and looks likely to face Tommy Paul, who is fresh from defeating Alex Zverev in the same event. The ever-improving American may well be able to claim another notable scalp.
Taylor Fritz is probably worth opposing if he takes to the court against (probably) Botic van de Zandschulp given the injury issues he had during the latter stages of Indian Wells. His first Masters title will also likely have taken a heavy mental toll.
Having tested Rafael Nadal fully last week, Nick Kyrgios could clearly cause problems for Andrey Rublev, while Denis Shapovalov won’t be relishing a scrap with Lloyd Harris, particularly if the South African is on a good serving day.
Best Outright Pick
Jannik Sinner made the final in Miami last season and he can go one better at a decent price this time around.
With Novak Djokovic and Rafael Nadal both absent, Daniil Medvedev is the favorite but he’s never been past the last eight of this tournament and would probably admit that conditions here don’t favour his game that well.
Sinner looks a decent alternative at +3000.
He’s won 13 of 15 matches so far this year and should be much happier with the court set-up.
Andrey Rublev, who must put Indian Wells disappointment behind him, and Matteo Berrettini are the higher-ranked seeds in his quarter, with Alex Zverev a potential semi-final foe.
That’s a draw that could have been a lot worse so Sinner gets the thumbs up.
Play Fantasy Sports Here!
How to Watch ATP Miami
ATP Miami Information | |
What | ATP Miami Open |
Location | Miami, Florida, USA |
Time | Wednesday, March 23 to Sunday, April 3 |
How to Watch | Tennis Channel |
More Tennis Predictions & Odds
Andy Schooler
Andy is a sports journalist of more than 20 years’ experience and is a former betting editor of the UK-based website, Sporting Life. He has specialized in tennis for many years, previewing hundreds of ATP Tour events and reporting from tournaments such as the ATP Finals and Davis Cup final. Andy has also covered numerous other sports, with a particular interest in soccer and cricket.