Chargers quarterback Justin Herbert underwent surgery on his wrist (non-throwing) last week.
The Chargers are allowing almost one rushing touchdown per game to opposing running backs.
Eagles wide receiver A.J. Brown has 18 catches over his previous two games.
To close out Week 14 of the 2025-26 NFL season, the Los Angeles Chargers are hosting the Philadelphia Eagles.
The leading storyline heading into this game is Chargers quarterback Justin Herbert, who underwent wrist surgery in his non-throwing hand. He's expected to suit up, but that wrist is going to be something to watch for throughout the night.
As for the Eagles, they're tied for third in Super Bowl odds of +900.
Both teams are also inside the top 13 in our NFL defense rankings, with the Chargers at No. 10 and the Eagles at No. 13. We also have the Chargers as the third-best pass defense.
With that being said, below, I've constructed a three-same Same Game Parlay for this matchup with +430 odds at Fanatics Sportsbook.
Odds below for two props are courtesy of Fanatics Sportsbook. Sign up for a Fanatics account today and receive up to $2,000 in FanCash. Find more details in our Fanatics Sportsbook review.
| Best Chargers vs Eagles SGP Picks | Odds | Get Up $2,000 in FanCash at Fanatics |
|---|---|---|
| Leg 1: Eagles -2.5 | -115 | CLAIM HERE |
| Leg 2: Saquon Barkley Anytime TD | +105 | CLAIM HERE |
| Leg 3: A.J. Brown 60+ Receiving Yards | -110 | CLAIM HERE |
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Heading into this game, I’m worried about Chargers quarterback Justin Herbert. Yes, he injured his non-throwing hand, but he had surgery, and it’s still up in the air if he’ll play or not, depending on the swelling.
I worry because he’s going up against an Eagles team that’s tied for sixth in the league in pressures with 179, and his offensive line has allowed the second-most pressures at 194, and he’s been sacked 40 times (tied for sixth).
The Chargers' defense has been playing fairly well recently, allowing just 142 passing yards per game over their last three games, but they’ve also only faced the Las Vegas Raiders, Jacksonville Jaguars, and Pittsburgh Steelers.
At full strength, I trust Herbert more than Eagles quarterback Jalen Hurts right now, but with his injury and that general discomfort, along with the Eagles’ pass rush, I think it might create problems.
Not only that, it’s not yet clear whether running back Omarion Hampton will be back either.
Too many variables for me; I’ll take the Eagles.
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While Barkley hasn’t scored in four games, I think he has a great chance to in this matchup.
The Chargers are allowing 0.92 rushing touchdowns per gam to running backs, which is tied for the fifth-highest rate in the NFL. This is coming despite running backs averaging just 18.92 carries per game against them, which is sixth-fewest.
They gave up three rushing scores to the Jaguars two weeks back. Sure, they’ve allowed those three over their last five games, but look at their opponents: the Minnesota Vikings, Tennessee Titans, Steelers, Jaguars (three touchdowns), and Raiders.
Yeah, none of them are exactly imposing offenses.
The Eagles call a run play 46.98% of the time, which is the seventh-highest rate in the NFL, and Barkley is responsible for 60.6% of the team’s carries.
I think he’ll get some more volume here than in the last two games and score.
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It’s been an up-and-down season for the Eagles as a whole, but for Brown specifically. Yes, he leads the team with a 26.9% target share, but he’s had six games with fewer than 50 receiving yards and even two games with single-digit yards.
However, he’s been heating up the past two weeks, catching 18 passes for 242 yards and three touchdowns.
He’s posted a 33.3% target share, with DeVonta Smith behind him at 28.8%.
Finally, the Chargers mostly play Cover-3 and Cover-4, and this season, 51.8% of his catches and 47.2% of his yardage production have come against those specifically.
I believe he’ll continue to get targets here and hit 60 yards, which he’s done in four of his last six games.
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