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UFC 321: Aspinall vs. Gane - Odds, Predictions & Picks

Published: October 24, 2025, 11:30 AM ET
8 min read
  • Aspinall defends his title for the first time against Gane

  • Vacant Strawweight title is on offer for Jandiroba and Dern

  • Nurmagomedov takes on Bautista in Bantamweight clash

UFC Fight Night 321: Aspinall vs. Gane Odds

The odds for this match are provided by the FanDuel Sportsbook. Place your bets at FanDuel and get $300 in Bonus Bets with a winning wager.

FighterOdds
(C) Tom Aspinall-480
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Ciryl Gane+330
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FighterOdds
Virna Jandiroba+132
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Mackenzie Dern-170
BET HERE
FighterOdds
Umar Nurmagomedov-530
BET HERE
Mario Bautista+360
BET HERE
FighterOdds
Alexander Volkov+158
BET HERE
Jailton Almeida-205
BET HERE
FighterOdds
Aleksandar Rakić-106
BET HERE
Azamat Murzakanov-120
BET HERE

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UFC Fight Night 321 Aspinall vs. Gane

UFC Fight Night 321: Aspinall vs. Gane - Picks & Predictions

Tom Aspinall vs. Cyril Gane - Heavyweight Championship

Virna Jandiroba vs. Mackenzie Dern - Women’s Strawweight Championship

Umar Nurmagomedov vs. Mario Bautista - Bantamweight Division

Alexander Volkov vs. Jailton Almeida - Heavyweight Division

Aleksander Rakic vs. Azamat Murzakanov - Light Heavyweight Division

Tom Aspinall vs. Cyril Gane - Heavyweight Championship

ASPINALLTALE OF THE TAPEGANE
32AGE35
6 ft 5 inHEIGHT6 ft 4 in
78 inREACH81 in
15-3-0RECORD13-2-0

The main event of UFC 321 will see champion Tom Aspinall defend his belt against Cyril Gane.

Aspinall will be feeling the pressure going into this fight: the first time he puts his title on the line since winning the interim championship in July 2024 against Curtis Blaydes. The first round saw Blaydes throw a left, which Aspinall was quick to capitalize on, countering it with a jab of his own, flooring his opponent. He seized the opportunity and finished Blaydes off with a series of ground strikes.

There’s been a big conversation about whether Aspinall deserves the championship since Jon Jones retired. Abu Dhabi will be his chance to show the world of mixed martial arts that he is worthy of holding the belt.

In Aspinall’s way is Cyril Gane, the number one contender, who will be looking to leave the UAE with the belt around his waist. Gane enters the fight following two consecutive victories, with the last being against Alexander Volkov in December. The fight went the distance with Gane declared the victor by split decision.

Gane has got a lot to prove this weekend. He will have been working meticulously with his camp at the MMA Factory to ensure that he walks away from UFC 321 as the best fighter in his division.

We’ve got Aspinall retaining his belt, and you can bet on him at -480 odds with FanDuel.

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Virna Jandiroba vs. Mackenzie Dern - Women’s Strawweight Championship

JANDIROBATALE OF THE TAPEDERN
37AGE32
5 ft 3 inHEIGHT5 ft 4 in
64 inREACH63 in
22-3-0RECORD15-5-0

After current champion Zhang Weili vacated her championship to pursue glory in the Flyweight division, the belt is up for grabs. Virna Jandiroba and Mackenzie Dern face off to capture it.

Jandiroba is on a hot streak, winning her last five fights. In her most recent fight against Yan Xiaonan, she picked up the win via unanimous decision. The Brazilian is a master of submissions, finishing 64% of her fights with her opponents tapping. We expect she’ll be looking to lock something in to gain the vacant Strawweight championship in the Etihad Arena.

Mackenzie Dern knows a thing or two about submissions herself. Dern holds the record for the most wins by submission in the division. She ended her last fight with her opponent Amanda Ribas’ tapping after receiving an armbar in the third. This fight will put Dern to the test, as she is fighting one of the most skilled fighters within the division, something her camp has definitely been preparing her for.

FanDuel has Dean walking away victorious, and you can bet on her at -170 odds.

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Umar Nurmagomedov vs. Mario Bautista - Bantamweight Division

NURMAGOMEDOVTALE OF THE TAPEBAUTISTA
29AGE32
5 ft 8 inHEIGHT5 ft 9 in
69 inREACH69 in
18-1-0RECORD16-2-0

This Bantamweight clash is shaping up to be a battle Umar Nurmagomedov and Mario Bautista will duke it out to firm up their positions within the division.

Nurmagomedov entered the sport with a heavy burden of expectation. He is the cousin of arguably one of the greatest fighters the UFC has ever had to offer in Khabib Nurmagomedov. Umar has lived up to these expectations, only picking up one loss which came in his last fight against Merab Dvalishvili. That fight went all five rounds and Nurmagomedov left unvictorious and unable to capture the championship. He will have been working with his team at AKA to avoid a repeat of that result and regain some momentum.

Bautista comes into UFC 321 hot, winning his last eight fights. In June, he faced off against Patchy Mix, and took the fight to the end of three rounds where he was determined the victor by the panel of judges. As a fighter, Bautista tends to favor holds. Unfortunately for him, his opponent has been trained by one of the greatest grapplers the sport ever witnessed, so he might have a bit of a mission if he decides to take this approach.

We’ve got Dagestani Nurmagomedov winning here. Get -530 odds on him with FanDuel today.

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Alexander Volkov vs. Jailton Almeida - Heavyweight Division

VOLKOVTALE OF THE TAPEALMEIDA
36AGE34
6 ft 7 inHEIGHT6 ft 3 in
80 inREACH79 in
38-11-0RECORD22-3-0

This Heavyweight bout will have serious consequences on the rest of the division as Alexander Volkov faces Jailton Almeida.

Volkov was unlucky in his last fight against Ciryl Gane, with the fight going the distance but Volkov was ultimately judged the loser. He will be looking to show the division he is a force to be reckoned with and he needs to do this by picking up the win against Almeida. Volkov has a fair few inches on Almeida. It will be interesting to see if he can use his monstrous size to his advantage.

Almeida enters this fight after picking up a victory against Serghei Spivac in January. He was able to mount his opponent’s back and finish him off with a series of punches to the head, making the referee stop the fight. He will need to muster up everything he has against the giant that is Volkov if he wants to add a third win to his streak.

Bookmakers have Almedia ahead, but we think otherwise. Head to FanDuel to get +158 odds on Volkov.

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Aleksandar Rakić vs. Azamat Murzakanov - Light Heavyweight Division

RAKIĆTALE OF THE TAPEMURZAKANOV
33AGE36
6 ft 4 inHEIGHT5 ft 10 in
78 inREACH71.5 in
14-5-0RECORD15-0-0

The first fight on the main card has Aleksander Rakić taking on Azamat Murzakanov in a bout that will have serious repercussions for the rest of the Light Heavyweight division.

Aleksander Rakić has had a few disappointments coming into this fight, losing three in a row. October saw him clash with Magomed Ankalaev: after three rounds the judges favored Ankalaev’s performance. Rakić needs to pick up the victory against Murzakanov if he wants to be seen as a formidable force within the promotion. He is going to have to use his massive size to his advantage.

Murzakanov has had a fantastic career so far, winning all of his 15 fights. In June, he knocked out Brendson Ribeiro after connecting with a left hook and following it up with a few ground strikes to seal the deal. Murzakanov will be in search of another KO victory, as he has been able to end 73% of his fights in this manner.

We are backing the undefeated Murzakanov in this fight, and you can too with -120 odds at FanDuel at the time of writing.

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How to Watch UFC 321: Aspinall vs. Gane

  • Location: Etihad Arena, Abu Dhabi, United Arab Emirates

  • When: Saturday, October 25

  • Time: 07:00 PM

  • How: PPV

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