MLS Cup Outrights Odds and Prediction: Messi and Co. Emerge as Favourites

• Inter Miami CF will try to be the first team since 2012 to defend the league crown in consecutive campaigns  

• MLS’ biggest spenders LAFC, Galaxy and Atlanta United are in the thick of the competitions to knock off Vice City

Last year's MLS Cup holders, Inter Miami CF, will look to become the first team since 2011 and 2012 to win the title in back-to-back seasons when the LA Galaxy carried out this feat. Throughout the 2026 season, Messi and Co. Will be favoured by the books and public to repeat as champions of MLS.

Below we share our pick to win the 2026 MLS Cup, the latest trends, and other information to help you pick a winner this season.

Major League Soccer Cup Winner Outrights Odds

The odds have been taken from the bet365 sportsbook. Sign up for a bet365 account with our promo code WSN365 and claim your bonus: Bet $5, Get $150 in Bonus Bets Win or Lose.

MLS Cup 2026 Winner Prediction

The reigning league winners from 2025 open this term as the favourites to claim this season's title. Inter Miami CF still retain the Argentinean legend on its squad, as Lionel Messi will be counted on once again to lead his side to the promise land. Vice City will be tasked with the difficult circumstance of repeating as league champions in this era of MLS which has seen rapid growth, this feat has not been successfully accomplished since the LA Galaxy did it in 2011 & 2012. The Herons don’t only have Messi at their disposal as a lethal attacking option, during the 2025 post season we saw the emergence of Mateo Silvetti. If Inter Miami can keep Tadeo Allende, they will be favourites throughout the season as his debut season in MLS saw him catalog 20 goals.

Los Angeles FC are perennial threats to claim the league title each season with the talent the club boasts. After getting bounced by the eventual Western Conference Champions, the Vancouver Whitecaps in a memorable conference semifinal, LAFC will be out for vengeance to add to their trophy cabinet. The 2022 MLS Cup Championships could overwhelm their adversaries in 2026 possessing the dynamic duo up front of Son Heung-min and Dennis Bouanga for a whole season. If one of the most devastating forward groups in the competition can remain healthy, Los Angeles FC could be in the MLS Cup conversation in early December.

The rest of the best are legitimate threats to disrupt the planned parade route Inter Miami and LAFC have in mind. The club from the north of the 49^th parallel, the Vancouver Whitecaps could make some noise with German soccer legend Thomas Müller getting a full training camp to start the season. San Diego FC enter their sophomore season with high hopes, especially when first year players in MLS like Anders Dryer and Hirving Lozano combining for 34 goals. Between 2020 and 2023, the Columbus Crew managed to celebrate two MLS Cups, a team who keeps a low profile but can flip the switch at the right moment making them instant contenders.

Bet $5 at bet365 and Get $150 in Bonus Bets

Who Will Win the 2026 MLS Cup - My Pick

Seattle Sounders (+1800) at bet365

Before we see the opening weekend of MLS, the Seattle Sounders are cataloged with the 10^th shortage odds to win this campaign's MLS Cup. The Sounders have yet to win the ultimate prize since 2019 and their most recent league final appearance occurred in 2020. The Rave Green have one of the most knowledgeable people on the touchline to lead this group of men to the big dance, with the solid resume Brian Schmetzer has constructed since his appointment in 2016. With two league titles, 2022 CONCACAF Champions Cup and a 2025 Leagues Cup win under his belt, Schmetzer knows how to get the best out of his troops.

Bet $5, Get $150 With Code WSN365 at bet365

How to Bet on the 2026 MLS Cup Winner

Simple and easy, head over to your preferred online sportsbook and navigate the MLS page. From there you will see a “Futures” tab, this is where you can wager on who you think will claim the 2025 MLS Cup.

Before placing your wager, we recommend betting within your limit and do some homework on what’s trending with team news and injuries to star players across the league. 

How to Read the 2026 MLS Cup Winner Odds

Especially if you're new to sports betting, reading the indicated odds can be overwhelming and confusing or if you are used to using a decimal or fraction system.

It’s quite easy to get the hang of it after a few minutes on studying how the read odds. The American system is basic, it uses a model where the plus sign (+) indicates the team is the underdog while the minus sign (-) means they are the favorite. If you see a team with no minus sign then the team with the lowest plus sign is considered the favourites. Numbers are based on $100 bets for example -120 means you need to bet $120 to win $100. +120 means if you bet $100, you'll win $120

Where to Bet on the 2026 MLS Cup Winner

In a growing industry, there is no shortage of online sportsbooks to choose from when placing your MLS Cup winner.

We like using bet365 sportsbook. New customers at bet365 can claim: after creating an account with our promo code WSN365. While Bonus Bets can’t be withdrawn for cash, they give players a chance to boost their bankroll without spending more real money.

Another great alternative website to use is FanDuel Sportsbook. Create a FanDuel account today and claim your welcome offer: Bet $5, Get $100 in Bonus Bets if Your Bet Wins. Read more about FanDuel Promo Code here.

MLS Cup History

In the top flight division, the LA Galaxy possess the bragging rights as the club with the most league titles, as they have won six MLS Cups since joining the competition in 1996. D.C. United have had their success early on lifting the trophy in four instances in their opening eight seasons in MLS, including forever being etched in history as they claimed the first-ever triumph winning it all in 1996.

Below is a list of the previous winners of the last ten seasons in MLS.