AFC East Odds, Predictions, Betting Picks 2025/26: The Patriots Deliver a Statement Win in Week 5

• Buffalo is averaging the third-most points scored per game (30.6/0

• The Patriots are averaging just 95.2 rush yards per game

• Tyreek Hill will miss the remainder of the 2025 season

The New England Patriots took out the NFL’s last remaining unbeaten team on Sunday Night Football in Week 5. It was a statement win for this young and exciting team, especially considering it was accomplished on the road. While the win moves them within a game of the division lead, can the Pats keep up this level of play for the remainder of the season?

Below, we will share the latest insights into all four AFC North squads, including the Bengals' ugly start, along with our pick to win. We’ll be using odds taken from bet365, which is offering new customers the chance to earn $200 in wagers when they bet $5, win or lose!.

Discover our podcast, Ride the Line, which is dedicated to all things sports and sports betting. Dive into Grant and Tanner's expert selections for the AFC East.

AFC East Odds

The odds have been taken from the bet365 sportsbook. Register at bet365 with our promo code WSN365 and claim the following welcome bonus: Bet $5, Get $200 in Bonus Bets Win or Lose.

AFC East Predictions

The Bills picked up their first loss of the season against the Pats in Week 5. While it was a statement win for New England, it’s hard to put too much stock into it. First off, the Patriots' defense was bailed out by three turnovers, which helped offset their poor play on third down. The win showed the Patriots are better than expected, but we don’t believe it changes this AFC East race.

Before we jump on the Pats bandwagon, we want to see them figure out their ground game. They are twenty-seventh in the league in rushing yards per game (95.2) as TreVeyon Henderson and Rhamondre Stevenson have both underwhelmed. Drake Maye and the pass attack have bailed them out, but that will change as the temperature drops late in the season. That is the fatal flaw of this young team, and is why we aren’t ready to believe in them quite yet.

The Miami Dolphins have become one of the sadder stories in the league. The team barely held off the Jets in Week 4 but blew a big lead against the Panthers in Week 5, dropping to 1-4. The loss of Tyreek Hill (season-ending IR) was evident, especially after Carolina began to mount their comeback. Considering the defense ranks twenty-ninth in yards allowed per game (386.6), it's hard to see Miami winning many games this season.

The Jets offense has looked better in 2025, at least when Justin Fields is healthy and playing. He has completed 67% of his passes for 754 yards and four passing TDs, while adding another 204 yards and three scores on the ground. With running back Breece Hall averaging 5.3 YPC, this unit is finding ways to move the ball. Unfortunately, their once-great defense has been a mess, allowing the second-most points (31.4) per game in the NFL.

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AFC East Winner Pick

Buffalo Bills (-450) at bet365 Sportsbook

The Bills seemed to take the Patriots for granted in Week 5, which led to a massive shift in odds to win the AFC East. The defense continues to look sharp, while the offense is averaging the third-most points per game (30.6) in the league. Look for this team to bounce back with wins against the Falcons and Panthers over the next three weeks, helping to re-establish them as the overwhelmingly favorite to win this division.

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How to Bet on the AFC East

Betting on the AFC East is easy, but learning where to find and place these bets can take time. If you find yourself stuck, we have you covered. 

Here is an easy step-by-step guide to help you get started:

1. Choose the sportsbook you want to wager with

2. Select “Football” or “NFL” from the betting catalog, usually found on the top or side menu

3. Click on the tab for “Futures”

4. Read through the options for the “Division Winner” section

5. Scroll down until you find the AFC East

6. Select the team you think will win

7. Navigate to your betslip to enter how much you want to wager

8. Hit submit, and you are all set!

All division futures bets will be paid out once the season ends and a champion is officially crowned. 

How to Read AFC East Odds

NFL futures odds work the same as any other bet. Each bet includes a number following the team or player, preceded by a plus or minus sign. 

A plus sign before the number usually indicates an underdog, which is common with futures bets. If the odds next to a team or player have a plus sign, that is the amount that you will win for every $100 you bet.

A minus sign usually indicates the favorite to win, though they are rarely seen for future bets. A minus sign in front of the odds means that is how much you need to bet to win $100.

For example, you bet $100 on the Patriots at +600 to win the AFC East. If they win the division, you will win $600. 

If you aren't looking to bet $100 at a time, don't worry! Check out our odds calculator to help you determine potential winnings based on different wager amounts.

Where to Bet on the AFC East

Are you ready to start betting on the AFC East but unsure where to start? If so, we have you covered with our sportsbook reviews. Here are our three favorite sportsbooks we use when betting on NFL futures:

• BetRivers Sportsbook: This sportsbook has been one of the few success stories from mid-size operators in the US. The platform isn’t as sharp as FanDuel or BetMGM, but it offers bettors some fantastic bonuses and very competitive odds. If you are looking for a smaller and more player-friendly platform, we highly recommend BetRivers. Claim the welcome offer today: $500 Bonus Bet.

• FanDuel Sportsbook: If you are betting on America’s favorite sport, why not use its favorite sportsbook? FanDuel offers bettors an easy-to-use platform that is easy to navigate. The odds, promotions, and rewards are unmatched, meaning you can have more money in your pocket when you win. Click our link and claim the bonus offer: Bet $5, Get $300 in Bonus Bets if Your Bet Wins.

• BetMGM Sportsbook: BetMGM has established itself as one of the top sportsbooks in the US. The platform captures the Las Vegas feel and allows players to bet on games easily. Be sure to pay attention to their fantastic loyalty program, which can lead to some big rewards. Use our code WSNSPORTS and claim your bonus today: Bet $10, Get $150 if You Win*.

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AFC East Winner History

The Bills won their fifth consecutive AFC East title in 2024. They have dominated the division since the fall of the Patriots, the only other team to win a division title in the last decade.

Below are the last ten teams to win the AFC East.