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Anytime Touchdown Scorer Predictions in Week 10: Back James Cook in a Divisional Matchup Against Miami

Published: November 5, 2025, 09:00 AM ET
5 min read
  • James Cook averaged 4.2 Yards per Carry in last week’s win against Kansas City

  • Cook is listed as one of the top contenders for the Offensive Player of the Year award

  • The Miami Dolphins' front seven ranks near dead last in Run Defense Win Rate

After sitting out of practice for a majority of the preseason, James Cook has been able to avoid getting off to a slow start as he is averaging nearly one touchdown per game at the halfway point of the season. Heading into week 10, expect Cook to continue to find the back of the end zone as he faces off against a Miami Dolphins front seven who struggles to stop the run.

For my selection of anytime TD picks, I've used odds from BetMGM Sportsbook. Join BetMGM with our promo code WSNSPORTS and get up to $1,500 back in the form of bonus bets* should you lose your first wager.

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Anytime Touchdown Scorer Predictions Week 10 Bills James Cook

James Cook Anytime Touchdown (-130) at BetMGM Sportsbook

Even with his underwhelming group of pass catchers struggling to create space for him, James Cook has been able to consistently reach the second level of the defense as he ranks top-10 in Yards Over Expected per Attempt. His offensive line has played a major role in his success this season as the Bills front five reside near the top of the board in Run Block PFF Grade.

In an AFC East divisional matchup against Miami, Cook will have a great opportunity to build on his momentum as the NFL Offensive Player of the Year contender faces off against a Dolphins front seven who ranks below league average in Run Defense Win Rate. For some more exposure, escalator bet Cook’s anytime touchdown scorer prop by placing smaller wagers on his alternate totals.

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Kyren Williams Anytime Touchdown (-120) at BetMGM Sportsbook

It has been a quiet start to the year for Kyren Williams in regard to scoring as the Los Angeles Rams running back has only scored three rushing touchdowns in eight games. An odd performance, especially when factoring in his heavy workload as Williams comfortably leads the team in total Red Zone Carries with a 72.7% Usage Rate.

While Williams has struggled to score on the ground, he has been far more efficient through the air as he has turned three of his seven receptions into touchdowns. With the Minnesota Vikings blitzing at the heaviest rate in the league, Williams will have a great opportunity to counter their pressure by screening to the outside for a potential dump off and score his fourth receiving touchdown of the season.

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Keenan Allen Anytime Touchdown (+200) at BetMGM Sportsbook

After a brief stint with the Chicago Bears, Keenan Allen has been able to round back into competitive form with the Los Angeles Chargers as he is currently averaging 57.8 Receiving Yards per game and 10.4 Yards per Reception. When in scoring position, Justin Herbert has consistently looked towards Allen’s way as he also leads the team in total Red Zone Targets while converting 80% of his Receptions into touchdowns.

Heading into Sunday, Allen will continue to thrive in the shortened field as he faces off against a Pittsburgh Steelers defense who ranks below league average in Def DVOA and in EPA. The emergence of Oronde Gadsden II also helps pull defensive attention away from Allen which increases his chances of breaking away from their coverage to create a high quality passing lane for Herbert to throw to. 

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Aaron Jones Anytime Touchdown (+150) at BetMGM Sportsbook

After sitting out for a majority of the year due to injury, Aaron Jones has managed to quickly find his footing as he finished last week’s contest against Detroit with 78 rushing yards while averaging 8.6 Yards per Carry. In a favorable matchup against Baltimore, expect Jones to continue to generate explosive runs as he faces off against a Ravens front seven who ranks below league average in Adjusted Line Yards.

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Kody Malstrom WSN Contributor

Kody Malstrom

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Kody Malstrom is a sports betting journalist with six years of writing experience in the industry. He covers an abundance of sports, including College Football, NFL, College Basketball, NBA, and more. Born and raised in Michigan, Kody is a devoted Detroit Sports fan and spends his Sundays rooting for the Detroit Lions while telling himself this year is the year they win it all. When not staring at betting markets, Kody spends his free time at the beach in the summer or snowboarding in the winter.
Email: kody.malstrom@wsn.com
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