NFL Comeback Player of the Year Odds & Predictions: Christian McCaffrey Locked the Award?

• The 49ers running back, Christian McCaffrey, has moved to an overwhelming favorite after dominating the Bears with over 180 scrimmage yards in Week 17.

• While McCaffrey pulled away, Jaguars quarterback Trevor Lawrence separated himself as the clear second choice by leading Jacksonville to their seventh straight win.

• Dak Prescott’s odds drifted significantly despite decent stats due to the Cowboys' lack of team success.

The NFL Comeback Player of the Year is awarded annually to a player who overcomes personal adversity and reminds the world of what hard work and determination can do. Sportsbooks have updated their odds for who they believe are in the best position to win the 2025 Comeback Player of the Year award.

NFL Comeback Player of the Year Odds

The odds have been taken from the FanDuel sportsbook. Register at FanDuel and claim the following welcome bonus: Bet $5, Get $100 in Bonus Bets if Your Bet Wins.

NFL Comeback Player of the Year Winner - My Pick

Christian McCaffrey (-2500) at FanDuel Sportsbook

Christian McCaffrey is the prohibitive favorite for Comeback Player of the Year. He combines the quintessential "return from injury" narrative with MVP-caliber production. After missing the vast majority of the previous season due to lingering Achilles issues, McCaffrey has not merely returned to the field but has reclaimed his status as the league's most versatile offensive weapon, serving as the engine of a surging 49ers team that has won six straight games.

Voters historically prefer candidates who return to elite status rather than just "good" status, and the fact that McCaffrey is simultaneously a top contender for Offensive Player of the Year makes his comeback case nearly impossible for a lower-tier quarterback like Trevor Lawrence to match.

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How to Bet on the NFL Comeback Player of the Year

There’s no league more popular for American sports bettors than the NFL. Every sportsbook should have a section dedicated to the NFL, and the Comeback Player of the Year odds, if available, should be listed under the “Futures” section. 

Futures bets are different from major markets in that they pertain to long-term events. In the case of the Comeback Player of the Year, the winner won’t be announced until the year-end player awards.

Certain states do not allow individual player futures bets, which would eliminate them from providing odds on the NFL Comeback Player of the Year. Check your state’s rules and sportsbook to see if your state qualifies.

How to Read NFL Comeback Player of the Year Odds

Reading Comeback Player of the Year odds is the same as reading odds in any other market. Odds values preceded by a + indicate that a bettor will win the listed amount with a $100 wager—for example, a winning wager at +400 odds will result in a $400 profit for a $100 bet.

Conversely, odds values led by a - imply that a bettor must risk the listed amount to win $100. So, -550 odds suggest a bettor must wager $550 to profit $100.

Where futures odds can be different from limited-outcome markets is that the favorite is not always or even usually indicated by a negative odds value. The more candidates there are, the more likely it is that all outcomes have positive odds, especially early in the NFL season.

Where to Bet on NFL Comeback Player of the Year Winner

As we mentioned, the NFL is the most popular sports league in America. NFL betting, including a variety of futures markets, should be available at every reputable sportsbook.

For this piece, we have used odds from Caesars Sportsbook. It's a great choice for NFL betting, and sports betting in general. Their odds are posted and refreshed timely, you can find odds boost and new users are eligible for a generous welcome offer: Bet Match up to $250 - Win or Lose. Just don't forget to use our promo code WSN250BM during the sign-up process.

As an alternative, have a look at FanDuel Sportsbook. FanDuel is among the most popular sportsbooks available in the US and offers a great selection of NFL bets, so you should be covered throughout the season. New users who sign up for a new account through our link will get the following offer: Bet $5, Get $100 in Bonus Bets if Your Bet Wins. No promo code is necessary.

NFL Comeback Player of the Year Winner History (Since 2000)