NFL Most Rushing Yards Odds and Predictions: Jonathan Taylor Leads the Field

• Indianapolis Colts RB Jonathan Taylor held his position by rushing for over 120 yards in Week 13, and pushed his season total to 1,282 yards.

• Buffalo Bills RB James Cook saw his odds shorten significantly after a dominant 144-yard performance against the Steelers.

• The gap between the top two and the field widened considerably, causing the odds for Jahmyr Gibbs (Lions) and De'Von Achane (Dolphins) to lengthen significantly.

NFL Rushing Yards Leader Odds

Odds below are provided by Caesars Sportsbook. Use our promo code WSN20X to sign up for an account and claim: Bet $1, Double Your Winnings Next 20 Bets.

My NFL Rushing Yards Leader Pick - Jonathan Taylor (-225) at Caesars

Jonathan Taylor holds the statistical lead with 1,282 yards through 13 weeks, maintaining a critical 54-yard cushion over his closest rival, James Cook. Taylor's candidacy is fortified by his elite usage rate in head coach Shane Steichen's offense, where he averages nearly 19 carries per game behind one of the league's top offensive lines. This heavy workload, combined with a career-high efficiency of 5.7 yards per carry, ensures he consistently produces high-yardage totals regardless of game script.

With the Colts remaining competitive in the AFC playoff race, Taylor is guaranteed to remain the focal point of their attack, giving him the safest floor and highest ceiling to secure his second career rushing title.

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How to Bet on the NFL Rushing Yards Leader

The only way to bet on the NFL rushing yards leader is through the futures betting market. There are alternate ways you can bet on rushing yards, though. 

Many of the best online sportsbooks have over/under futures lines for each player, and you can also bet on each player's rushing yards on a per-game basis. 

How to Read NFL Rushing Yards Leader Odds

Looking at the odds above, you'll notice that each player has a "+" next to their name. This is typical during the preseason when there’s still a lot of uncertainty and games haven't started. As the season progresses and player stats start to separate the contenders, you’ll begin to see “-” odds appear for the frontrunners.

Let's examine how to read these odds through the lens of winning $100 or wagering $100.

• “+” odds indicate how much you’d win on a $100 bet. For instance, if Barkley is listed at +650, a $100 wager would return $650 in winnings.

• “-” odds show how much you must bet to win $100. So, if Barkley were -650, you’d have to wager $650 just to win $100.

Where to Bet on NFL Rushing Yards Leader

The best places to wager on the NFL rushing yards leader right now are FanDuel, Caesars, and BetMGM. 

• Caesars Sportsbook: The odds above are from Caesars, and it was the first to offer these odds during the preseason. There’s a new player-friendly welcome bonus and frequent odds boosts. Use our promo code WSN20X to sign up for a Caesars account and claim the welcome offer: Bet $1, Double Your Winnings Next 20 Bets.

• FanDuel Sportsbook: Offers a sizable welcome bonus, great customer support, and tools for new players to understand the ins and outs of sports betting. Follow our link to claim the welcome bonus offer at FanDuel: Bet $5, Get $250 in Bonus Bets if Your Bet Wins.

• BetMGM Sportsbook: The largest welcome bonus on the market today, BetMGM offers some free-to-play games to earn bonus bets. Sign up for a BetMGM account with our promo code WSNSPORTS and get the following offer: Get Up to $1,500 in Bonus Bets*. Interested to learn more?

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NFL Rushing Yards Leader History

The rushing yards leader has been tracked yearly since 1932. In 1967, the Super Bowl era began. 

Below is the NFL's leading rusher every year since 2010. Since then, only one player has gone back-to-back as the league’s leading rusher.